Optimizing electrode configurations for EEG mild cognitive impairment detection.

The Optimal electrode configuration of Electroencephalograms (EEG) systems for mild cognitive impairment (MCI) detection and monitoring in non-clinical settings, i.e. number of electrodes and the positions of the electrodes, remains to be explored.

An exploration of the influencing factors of privacy fatigue among mobile social media users from the configuration perspective.

Privacy fatigue caused by privacy data disclose and the complexity of privacy control has become an important factor influencing people's privacy decision-making behavior. At present, academia mainly studies privacy fatigue as a key determinant to explain the privacy paradox problem, but there is insufficient attention to its influencing factors and specific pathway of occurrence. Exploring the antecedents of privacy fatigue is of great significance for alleviating users' subjective privacy detachment and promoting privacy protection.

MRI imaging characteristics of brainstem and midbrain aqueduct in patients with iNPH.

Idiopathic normal pressure hydrocephalus (iNPH) is frequently difficult to diagnose due to the absence of specific symptoms, yet early detection and surgical intervention are essential for preventing sequela such as irreversible dementia. This study explores the specific magnetic resonance imaging (MRI) features of the brainstem and mesencephalic aqueduct in patients with iNPH. Head MRI data of 50 iNPH patients and 30 healthy matched controls were compared for mesencephalic aqueduct length, diameter, and angle, structural features of the brainstem at the sagittal plane, brainstem component volume ratios, angle between the brainstem and spinal cord, and the area and morphology of the pontine cisterns.

The presence of pleural effusion is an independent prognostic factor in patients with malignant pleural mesothelioma.

Malignant pleural mesothelioma (MPM) is a rare form of thoracic malignancy with a poor prognosis. Pleural effusion (PE) occurs in the majority of patients with MPM; however, its impact on MPM outcomes remains controversial. We searched for eligible patients from the Surveillance, Epidemiology, and End Results (SEER) database, and clinicopathological information and outcomes were collected.

Correlation analysis of the triglyceride-glucose index and related parameters in metabolic dysfunction-associated fatty liver disease.

This study aimed to investigate the correlation and predictive value of TyG and related parameters with metabolic dysfunction-associated fatty liver disease (MAFLD) MAFLD. This study retrospectively included individuals who underwent health examinations and abdominal ultrasound from July 2021 to June 2024 at the Affiliated Hospital of Southwest Medical University, Sichuan Province, China. A total of 71,299 subjects' clinical and laboratory data were extracted, the correlation between TyG and related parameters and MAFLD was analyzed via univariate and multivariate logistic regression methods, and the nonlinear relationship between the TyG index and the risk of MAFLD was explored via restricted cubic spline (RCS) analysis.

Polypharmacy or potentially inappropriate medications among older adults with COVID-19 in a secondary hospital in China and their association with mortality.

Elderly patients with multiple concomitant chronic diseases are the particularly vulnerable during the Coronavirus disease 2019 (COVID-19) epidemic, which accounts for a large number of COVID-19-related deaths. The purpose of the study was to investigate the impact of polypharmacy and potentially inappropriate medications (PIMs) on in-hospital mortality in a secondary hospital in China. A cross-sectional, retrospective study was conducted using electronic medical data collected from Shanghai Gonghui Hospital from April 2022 to June 2022.

The role of user participation and psychological distance in consumer brand attitudes in gamified marketing.

With the rapid development of the digital age, in the business field, gamified marketing has been applied to practice by more and more enterprises, and has been studied by many scholars in the field of academic research. However, the existing research mainly focuses on the impact of gamification marketing activities itself on consumer behavior, and lacks the exploration of the design and mechanism of gamification marketing itself. The purpose of this paper is to find out the influence factors of gamification marketing language style on consumers' brand attitudes, and the empirical results have important theoretical significance and practical implication.

Moral disengagement as mediator and guilt as moderator between cyber moral literacy and cyberbullying among late adolescents.

The rapid growth of internet usage has led to increased cyberbullying among adolescents, with varying rates reported across countries. This study aimed to investigate the impact of cyber moral literacy on cyberbullying among late adolescents, examining both the mediating role of moral disengagement and the moderating effect of guilt on the relationship between cyber moral literacy and cyberbullying. Data were collected from 7837 late adolescent students (aged 18-21 years) at four universities in Sichuan Province, China.

Electrolyte design for reversible zinc metal chemistry.

Metal anodes hold significant promise for next-generation energy storage, yet achieving highly reversible plating/stripping remains challenging due to dendrite formation and side reactions. Here we present a tailored electrolyte design to surpass 99.9% Coulombic efficiency (CE) in zinc metal anodes by co-engineering salts and solvents to address two critical factors: plating morphology and the anode-electrolyte interface.

Development and validation of a real-time prediction model for acute kidney injury in hospitalized patients.

Early prediction of acute kidney injury (AKI) may provide a crucial opportunity for AKI prevention. To date, no prediction model targeting AKI among general hospitalized patients in developing countries has been published. Here we show a simple, real-time, interpretable AKI prediction model for general hospitalized patients developed from a large tertiary hospital in China, which has been validated across five independent, geographically distinct, different tiered hospitals.

The protein circPETH-147aa regulates metabolic reprogramming in hepatocellular carcinoma cells to remodel immunosuppressive microenvironment.

Metabolic reprogramming fuels cancer cell metastasis and remodels the immunosuppressive tumor microenvironment (TME). We report here that circPETH, a circular RNA (circRNA) transported via extracellular vesicles (EVs) from tumor-associated macrophages (TAMs) to hepatocellular carcinoma (HCC) cells, facilitates glycolysis and metastasis in recipient HCC cells. Mechanistically, circPETH-147aa, encoded by circPETH in an m6A-driven manner, promotes PKM2-catalyzed ALDOA-S36 phosphorylation via the MEG pocket.

Nucleophilic addition of bulk chemicals with imines using N-functionalized hydroxylamine reagents as precursors.

C-C and C-X bond forming reactions are essential tools in organic synthesis, constantly revolutionizing human life. Among the key methods for constructing new chemical bonds are nucleophilic addition reactions involving imines. However, the inherent challenges in synthesizing and storing imines have stimulated interest in designing stable precursors, which generates imines in situ during the reaction.

The independent and combined associations of nocturnal sleep duration, sleep midpoint, and sleep onset latency with global cognitive function in older Chinese adults.

This study aims to investigate the independent and combined associations of nocturnal sleep duration, sleep midpoint, and sleep onset latency with global cognitive function in older Chinese adults. Our cross-sectional study included 4601 community-dwelling cognitively unimpaired adults aged 60 years or older from the West China Health and Aging Cohort Study. Sleep characteristics were assessed using the Pittsburgh Sleep Quality Index, and global cognitive function was evaluated using the Mini-Mental State Examination (MMSE).

Comprehensive geological analysis and evaluation of the feasibility of renovating the Wanshunchang gas reservoir into a gas storage facility.

As many oil and gas reservoirs approach depletion stages in the future, alongside growing energy storage demands, constructing gas storage facilities becomes critical for ensuring a stable natural gas supply. Consequently, a comprehensive geological analysis is essential to evaluate the feasibility of converting depleted gas reservoirs into gas storage facilities. The W gas reservoir in the Sichuan Basin, China, is nearing depletion and presents potential for conversion into a gas storage facility.

Development of nanofiber facial mask inspired by the multi-function of dried ginger (Zingiberis Rhizoma) essential oil.

Plant extracts, especially herbal extracts, are in line with the cosmetics development trend of natural and safe in today's world. Dried ginger essential oil (DGEO) is a fragrant oily liquid extracted from the dried roots of Zingiber officinale Rosc. This research investigated DGEO could effectively inhibit Staphylococcus aureus and Propionibacterium acnes.

A comparative analysis of lumboperitoneal shunt outcomes in patients with post-hemorrhagic and post-traumatic hydrocephalus.

Hydrocephalus, whether arising from post-hemorrhagic or post-traumatic origins, poses significant challenges in clinical management. Lumboperitoneal shunting (LPS) emerges as a viable therapeutic intervention, yet comparative analyses between these etiologies remain scarce. This retrospective study aims to compare the efficacy and safety of LPS placement in patients with post-hemorrhagic (PHH) and post-traumatic hydrocephalus (PTH).

Relationship between wind speed and plant hydraulics at the global scale.

Wind is an important ecological factor for plants as it can increase evapotranspiration and cause dehydration. However, the impact of wind on plant hydraulics at a global scale remains unclear. Here we compiled plant key hydraulic traits, including water potential at 50% loss of hydraulic conductivity (P), xylem-specific hydraulic conductivity (K), leaf area to sapwood area ratio (A/A) and conduit diameter (D) with 2,786 species-at-site combinations across 1,922 woody species at 469 sites worldwide and analysed their correlations with wind speed.

Research on wear and grinding models of high-speed turnouts based on semi-Hertz contact.

In order to reduce turnout rail wear, the paper establishes a coupled dynamics model and a turnout rail wear model that consider the true profile of the turnout rail, the vehicle's continuous traction force while passing, and the operational resistance. Comparative analysis of various models for predicting turnout rail wear indicates that the wear energy model is better suited for this purpose. The ideal profile update step for the turnout rail is 0.

Evaluating body roundness index and systemic immune inflammation index for mortality prediction in MAFLD patients.

Metabolic dysfunction-associated fatty liver disease (MAFLD) is a major cause of liver-related morbidity and mortality, contributing to both cardiovascular and non-cardiovascular deaths. The Body Roundness Index (BRI) and Systemic Immune-Inflammation Index (SII) have emerged as predictors of adverse outcomes in metabolic diseases. This study investigates the association between BRI, SII, and mortality risk in MAFLD patients.

Personalized tourism recommendation model based on temporal multilayer sequential neural network.

Personalized tourism has recently become an increasingly popular mode of travel. Effective personalized route recommendations must consider numerous complex factors, including the vast historical trajectory of tourism, individual traveler preferences, and real-time environmental conditions. However, the large temporal and spatial spans of trajectory data pose significant challenges to achieving high relevance and accuracy in personalized route recommendation systems.

Explainable quality assessment of effective aligned skeletal representations for martial arts movements by multi-machine learning decisions.

How to utilize modern technological means to provide both accurate scoring and objective feedback for martial arts movements has become an issue that needs to be addressed in the field of physical education. This study proposes an intelligent scoring method based on machine learning. Firstly, the key features are extracted by the feature alignment technique, which eliminates the influence of athletes' movement speed, rhythm and duration on the scoring, thus reflecting the athletes' skill level more realistically.

The dynamic oral-gastric microbial axis connects oral and gastric health: current evidence and disputes.

Emerging evidence indicates that oral microbes are closely related to gastric microbes and gastric lesions, including gastric atrophy, intestinal metaplasia and gastric cancer (GC). Helicobacter pylori is a key pathogen involved in GC. However, the increasing prevalence of H.

The hybrid lipoplex induces cytoskeletal rearrangement via autophagy/RhoA signaling pathway for enhanced anticancer gene therapy.

Delivering plasmid DNA (pDNA) to solid tumors remains a significant challenge due to the requirement for multiple transport steps and the need to promote delivery efficiency. Herein, we present a virus-mimicking hybrid lipoplex, composed of an arginine-rich cationic lipid, hyaluronic acid derivatives coated gold nanoparticles, and pDNA. This system induces cytoskeletal rearrangements through "outside-in" mechanical and "inside-out" biochemical signaling, overcoming intra- and intercellular barriers to enhance pDNA delivery.

Integrated multiomics signatures to optimize the accurate diagnosis of lung cancer.

Diagnosing lung cancer from indeterminate pulmonary nodules (IPLs) remains challenging. In this multi-institutional study involving 2032 participants with IPLs, we integrate the clinical, radiomic with circulating cell-free DNA fragmentomic features in 5-methylcytosine (5mC)-enriched regions to establish a multiomics model (clinic-RadmC) for predicting the malignancy risk of IPLs. The clinic-RadmC yields an area-under-the-curve (AUC) of 0.