62 results match your criteria: "Sichuan Science City Hospital[Affiliation]"

In this paper, we introduce an entirely new solar absorber design-a multi-layer periodic stacked structure. Through coupling effects, this design has perfect ultra-wideband absorption characteristics. The absorber structure is composed of four absorption units with varying cycle lengths, which are cyclically stacked on the surface of the refractory metal Cr.

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The main function of erythropoietin (EPO) is to promote hematopoiesis and improve anemia. In addition, EPO also has many non-hematopoietic effects such as anti-inflammation, anti-apoptosis and anti-oxidation. To achieve the protective effects, large doses of EPO are required, so the probability of side effects increases.

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Background: A screening tool was devised to aid the diagnosis and treatment of ground-glass nodules (GGNs).

Methods: The current ambispective cohort study included retrospective collation of 20 variables synthesizing a patient's clinical characteristics, serum tumor markers, and CT results, which allowed division into noninvasive (benign, atypical adenomatous hyperplasia, and adenocarcinoma in situ) and invasive (minimally invasive and invasive adenocarcinomas) tumors to build a prediction nomogram and GGN screening scale. The model was verified internally.

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While myofibroblasts are the key cause of abnormal extracellular matrix accumulation, the origin of which has not yet been fully elucidated. Recently, it has been found that macrophage-myofibroblast transformation (MMT) defined by the expression of both macrophage markers (F4/80 or CD68) and myofibroblast markers (α-SMA) is one of its important sources. In the process of MMT, it is unclear whether epor is involved.

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Cortical morphological changes and associated transcriptional signatures in post-traumatic stress disorder and psychological resilience.

BMC Med

October 2024

Mental Health Center and Psychiatric Laboratory, the State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, 610041, Chengdu, People's Republic of China.

Article Synopsis
  • Individuals who have experienced severe trauma can develop PTSD, with prevalence rates varying from 10 to 50%, while some unaffected people show psychological resilience; this study investigates the brain network changes and gene expression related to these conditions.
  • The research involved PTSD patients, trauma-exposed healthy individuals (TEHI), and healthy controls, analyzing their brain networks and gene expression patterns using advanced neuroimaging techniques.
  • Results indicated that TEHI exhibited both PTSD-like brain changes and unique neurobiological adaptations, revealing a complex interplay of gene expression and resilience mechanisms in response to trauma.
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Three peak metamaterial broadband absorbing materials based on ZnSe-Cr-InAs stacked disk arrays.

Dalton Trans

October 2024

School of Physics and Electronic-Information Engineering, Hubei Engineering University, Xiaogan 432000, China.

Metamaterial absorbers show great potential in many scientific and technological applications by virtue of their sub-wavelength and easy-to-adjust structure, with bandwidth as an important standard to measure the performance of the absorbers. In this study, our team designed a new broadband absorber, which consists of an indium arsenide (InAs) disk at the top, a zinc selenide (ZnSe)-chromium (Cr) stacked disk in the middle and a metal film at the bottom. Simulation results show that the absorber has remarkable absorptivity properties in the mid-long infrared band.

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A tale of two phenotypes: transition from hypertrophic to dilated cardiomyopathy in Danon disease.

Eur Heart J Case Rep

September 2024

Department of Magnetic Resonance Imaging, Fuwai Hospital and National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beilishi Road No. 167, Xicheng District, Beijing 100037, China.

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Objective: Femoral head necrosis is a challenging condition in orthopaedics, and the occurrence of collapse is an important factor affecting the prognosis of femoral head necrosis. Sclerosis bands are known to influence the collapse of the femoral head, yet there is a lack of research on the biomechanical role of sclerosis bands in non-vascularized fibular grafting surgery. This study aims to evaluate the biomechanical impact of sclerosis bands in femoral head necrosis and their role in non-vascularized fibular grafting surgery (NVFG) using finite element analysis.

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In this paper, a broadband solar absorber is constructed and simulated based on the finite difference time domain method (FDTD). The modeled structure of the absorber consists of cyclic stacking of five absorber cells with different periods on refractory metal W, where a single absorber cell is composed of a three-layer SiO-InAs-TiN square film. Due to the Fabry-Perot resonance and the surface plasmon resonance (SPR), an absorptivity greater than 90% within a bandwidth of 2599.

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Study Objective: We conducted this double-blinded randomized controlled trial to examine whether the combination of dexamethasone and dexmedetomidine as adjuvants of transversus abdominis plane (TAP) block could improve analgesia efficacy and duration for gastric cancer patients.

Design: Randomized controlled trial.

Setting: The preoperative area, operating room, postanesthesia recovery room and bed ward.

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Utilizing the phase transition principle of VO, this paper presents a tunable ultra-wideband terahertz perfect absorption device with simple structure and tunability. The proposed broadband terahertz perfect absorption device is a three-layer structure with a metal reflective layer, a silicon dioxide dielectric layer and a VO layer from bottom to top. It was found that the terahertz perfect absorption device's absorption could be dynamically adjusted from 1.

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Article Synopsis
  • Pudendal neuralgia is a painful condition affecting 5-26% of people and is treated through various methods, but drug therapy often provides limited relief.
  • This study investigates the effectiveness and safety of pulsed radiofrequency therapy alone versus in combination with ganglion impar block in patients who haven't responded to other treatments.
  • The trial will involve 84 participants, measuring pain and psychological outcomes while monitoring for side effects, with analysis focusing on differences between the treatment methods and various patient subgroups.
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Objectives To find out the prevalence rate of pre-myopia among primary school students in the Mianyang Science City Area, analyze its related risk factors, and thus provide a reference for local authorities to formulate policies on the prevention and control of myopia for primary school students. Methods From September to October 2021, Cluster sampling was adopted by our research group to obtain the vision levels of primary school students employing a diopter test in the Science City Area. In addition, questionnaires were distributed to help us find the risk factors associated with pre-myopia.

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We propose a structurally simple, innovative, and multifunctional mid-infrared broadband thermally tunable metamaterial absorption device. The absorption device consists of a three-layer structure, from bottom to top: Ti substrate, SiO dielectric layer, and patterned VO layer. Through temperature control, the average absorption intensity of the absorption device can vary between 0.

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The intensity and sensitivity of surface-enhanced Raman scattering (SERS) spectra are highly dependent on the consistency and homogeneity of the nanomaterials. In this study, we developed a large-area three-dimensional (3D) hotspot substrate with good homogeneity and reproducibility in SERS signals. The substrate is based on the synergistic structures of nanoporous gold (NPG) and gold nanoparticles (AuNPs).

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Background: Pressure wire fractional flow reserve (FFR) and its derivatives, such as quantitative flow ratio (QFR), computational pressure flow-derived FFR (caFFR), coronary angiography-derived FFR (FFR), and computed tomography-derived FFR (FFR), have been validated for identifying functionally significant stenosis and guiding revascularization strategy. The limitations of using these methods include the side effects of hyperemia-induced agents, additional costs, and vulnerability to microvascular resistance. FFR is related both to the degree of a stenotic coronary artery and to its subtended myocardial territory.

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Importance: It is uncertain whether intravenous methylprednisolone improves outcomes for patients with acute ischemic stroke due to large-vessel occlusion (LVO) undergoing endovascular thrombectomy.

Objective: To assess the efficacy and adverse events of adjunctive intravenous low-dose methylprednisolone to endovascular thrombectomy for acute ischemic stroke secondary to LVO.

Design, Setting, And Participants: This investigator-initiated, randomized, double-blind, placebo-controlled trial was implemented at 82 hospitals in China, enrolling 1680 patients with stroke and proximal intracranial LVO presenting within 24 hours of time last known to be well.

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Purpose: This study aims to comprehensively evaluate the efficacy and safety of programmed cell death protein-1 (PD-1) in patients with advanced, recurrent, or metastatic cervical cancer (ARMCC) and identify the population that may benefit the most.

Methods: We conducted a search of PubMed, EMBASE, and the Cochrane Collaboration Library from their inception to September 2023. We extracted and analyzed the results related to the efficacy and safety of PD-1 in patients with ARMCC.

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Iridium-catalyzed selective arylation of B(6)-H of 3-aryl--carboranes with arylboronic acid direct B-H activation.

Chem Commun (Camb)

January 2024

School of Pharmacy & State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China.

This work discloses an iridium-catalyzed selective arylation of B(6)-H of 3-Ar--carboranes with arylboronic acid direct B-H activation for the first time. A series of unsymmetric and symmetric 3,6-diaryl--carboranes decorated with diverse active groups have been synthesized with moderate to excellent yields under mild conditions. This work offers an efficient approach for selective arylation of B(6)-H with arylboronic acid and has important value for selective functionalization of -carboranes.

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Economic burden attributable to healthcare-associated infections at western China hospitals: 6 Year, prospective cohort study.

J Infect

February 2024

Healthcare-associated Infection Control Center, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, China.

Article Synopsis
  • Healthcare-associated infections (HAIs) pose significant risks to patient safety and come with substantial economic costs, but there's limited data linking these costs to Medicare in western China, prompting this study.
  • The study compared medical costs of patients with HAIs to those without HAIs over six years at 34 hospitals, utilizing data from 2016 and 2022 to identify trends and cost growth.
  • Findings revealed that older patients with HAIs in 2022 faced much higher hospital costs compared to those without HAIs, indicating worsening economic impacts associated with these infections over time.
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Chinese doctors are required to inform patients' direct relatives of a cancer diagnosis rather than the patients themselves. The disease may be hidden from patients by their family members, which could result in severe outcomes. We selected postoperative T3 esophageal cancer (EsC) patients hospitalized from June 2015 to December 2019 as research subjects.

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F-FDG PET/CT-based radiomics model for predicting the degree of pathological differentiation in non-small cell lung cancer: a multicentre study.

Clin Radiol

January 2024

Center for Molecular Imaging Probe, Hunan Province Key Laboratory of Tumour Cellular and Molecular Pathology, Cancer Research Institute, Hengyang Medical School, University of South China, Hengyang, Hunan 421001, China. Electronic address:

Aim: To explore the value of 2-[F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography (PET)/computed tomography (CT)-based radiomics model for predicting the degree of pathological differentiation in non-small-cell lung cancer (NSCLC).

Materials And Methods: Clinical characteristics of 182 NSCLC patients from four centres were collected, and radiomics features were extracted from F-FDG PET/CT images. Three logistic regression prediction models were established: clinical model; radiomics model; and nomogram combining radiomics signatures and clinical features.

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The coronavirus disease 2019 (COVID-19) epidemic has given a warning that it is important to explore the rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical specimens or environmental samples for public health strategies and future variants. The surface-enhanced Raman spectroscopy (SERS) technique was demonstrated to achieve this goal. However, the consistency of signals originating from the poor compatibility of virions with SERS hotspots remains a key scientific challenge for the practical applications of SERS.

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To achieve high-accuracy urine specific gravity discrimination and guide the design of four-waveband multispectral sensors. A modified combination strategy was attempted to be proposed based on the successive projections algorithm (SPA) and the spectral index (SI) in the present study. First, the SPA was used to select four spectral variables in the full spectra.

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Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating and life-threatening stroke subtype, that has a high disability and fatality rate. By the use of the systemic immune-inflammation index (SII), it is possible to understand the pathophysiology that underlies immune and inflammatory responses and anticipate consequences including delayed cerebral ischemia (DCI), delayed cerebral vasospasm, and functional outcome. A systematic search of the English-language literature in PubMed and Embase was performed to locate articles addressing the usage of SII in aSAH patients.

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