51 results match your criteria: "Shuuwa General Hospital[Affiliation]"

Article Synopsis
  • The study examines clinical outcomes of two treatment options for distal anterior cerebral artery (DACA) aneurysms: microsurgery and endovascular treatment (EVT).
  • It analyzes data from 166 patients across 16 stroke centers, comparing the efficacy, complications, and recurrence rates of both treatments over a median follow-up of 15.3 months.
  • Findings suggest that while EVT may be a viable alternative to microsurgery, especially for unruptured aneurysms, it shows higher recurrence and retreatment rates, particularly in cases of ruptured aneurysms, highlighting the need for careful monitoring.
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Background And Objectives: Although intraprocedural rupture (IPR) is rare, it is a devastating complication of endovascular treatment (EVT) for intracranial aneurysms. Very few studies have been conducted on IPR, and the safety and efficacy of management techniques of IPR have not been investigated.

Methods: Patients who experienced IPR during EVT between 2013 and 2022 were enrolled from a multicenter observational registry.

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Contact aspiration for basilar artery occlusion safely reduces the puncture-to-recanalization time.

Clin Neurol Neurosurg

July 2024

Department of Endovascular Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. Electronic address:

Article Synopsis
  • This study investigates the effectiveness of first-line contact aspiration compared to other treatment strategies for basilar artery occlusion in endovascular thrombectomy.
  • A total of 84 patients from 16 Japanese stroke centers were analyzed, with findings showing no significant differences in recanalization rates but indicating contact aspiration led to faster results.
  • The results suggest that while contact aspiration gives better functional outcomes, the main advantage is a significantly shorter time from puncture to successful recanalization.
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Article Synopsis
  • * In an experiment using wild-type and CRTH2-knockout mice sensitized with ovalbumin (OVA) without an adjuvant, it was found that CRTH2 KO mice exhibited significantly reduced airway hyperresponsiveness (AHR) and lower levels of eosinophils and type-2 cytokines in comparison to wild-type mice.
  • * The study concludes that CRTH2 plays a critical role in the development of asthma responses in models of airway
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Carotid webs cause ischemic stroke in young people and are associated with a high rate of stroke recurrence. Histopathological examination is crucial for clarifying the pathogenesis and mechanisms underlying the occurrence of carotid webs, although the mechanisms generally remain unclear. Here, we report a case of a symptomatic carotid web in a woman in her 50s who had a medical history of two ischemic strokes.

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The patient was a 71-year-old woman diagnosed with mesenteric phlebosclerosis(MP)2 years earlier. CT performed to investigate her abdominal pain revealed an ascending colon obstruction. Colonoscopy(CS)revealed MP extending to the ascending colon hepatic flexure with stenosis and a cecal tumor(biopsy tub1).

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Aim: Assessing the indication for elective neuro-endovascular treatment (EVT) in older patients requires consideration of the impact of systemic comorbidities on their overall reduced life expectancy. The objective of this study was to determine the long-term outcomes of elective neuro-EVT in patients aged ≥80 years, and to investigate the impact of pre-existing cancer on their long-term outcomes.

Methods: Of the patients enrolled in multicenter observational registry, those aged ≥80 years undergoing elective neuro-EVT between 2011 and 2020 were enrolled.

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Objective: Sarcopenia and osteoporosis substantially influence health and lifespan. However, the variables affecting skeletal muscle mass (SMM) or bone mineral density (BMD) remain unknown.

Design And Methods: From August 1, 2018 to July 31, 2019, we conducted a single-center, observational cohort study with 291 Japanese adult patients on maintenance hemodialysis due to end-stage kidney disease, who had their femoral neck BMD measured using dual-energy X-ray absorptiometry.

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Article Synopsis
  • Atezolizumab plus bevacizumab is an effective treatment for intermediate-stage hepatocellular carcinoma (HCC), achieving a 44% response rate, and potentially allows for curative conversion through additional therapies like resection or ablation.
  • A study of 110 patients demonstrated that 35% achieved complete response (CR) after initial treatment, with various methods used for curative conversion, including resection and superselective TACE.
  • Overall survival rates were positive, with no deaths among CR patients and stable liver function scores post-treatment, although some patients did experience recurrence.
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Article Synopsis
  • The study aimed to explore how baseline infarct area and collateral status affect clinical outcomes in stroke patients with acute basilar artery occlusion after undergoing endovascular treatment.
  • It analyzed 86 patients treated within 24 hours, finding that those with a higher baseline infarct score (pc-ASPECTS ≥ 7) had better chances of recovery, with 43% achieving good outcomes.
  • It concluded that while pc-ASPECTS is a reliable predictor of positive clinical outcomes after treatment, the collateral status scores did not show a significant impact.
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A 75-year-old male patient underwent endoscopic submucosal dissection (ESD) for early gastric cancer. The ESD ulcer bleeding occurred 7 days post-ESD, and he underwent endoscopic clipping hemostasis. Afterward, the patient presented with acute cholecystitis and cholangitis, thereby developing sclerosing cholangitis.

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A 69-year-old woman with a history of otitis media with anti-neutrophil cytoplasmic antibody-associated vasculitis who had been receiving corticosteroid monotherapy presented with shortness of breath. The otitis media had been alleviated, but she had saddle nose. Chest enhanced computed tomography showed stenoses of the bronchi and large vessels surrounded by mass-like lesions in the mediastinum.

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Article Synopsis
  • The study aimed to determine how the location of brain infarcts, measured by the posterior circulation Alberta Stroke Program Early Computed Tomographic Score (pc-ASPECTS), affects patient outcomes after endovascular therapy for basilar artery occlusion.
  • Among 100 participants, 51% achieved favorable outcomes, with younger age, lower pre-treatment stroke severity, and higher pc-ASPECTS scores linked to better recovery.
  • The research concluded that higher pc-ASPECTS scores are predictive of better outcomes, while bilateral cerebellar infarction is associated with poorer recovery chances.
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Article Synopsis
  • Patients receiving hemodialysis (HD) have a higher prevalence of lower extremity artery disease (LEAD) compared to the general population, affecting treatment strategies and prognosis.
  • This study analyzed 2,321 patients, distinguishing between those with intermittent claudication (IC) vs. critical limb-threatening ischemia (CLTI), and found that CLTI is more common in HD patients.
  • HD patients showed a greater incidence of major adverse cardiovascular and cerebrovascular events (MACCE) and limb events at 24 months, particularly in the CLTI subgroup, while no significant differences were noted for limb events in the overall study group.
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A 72-year-old man received rifampicin, ethambutol and sitafloxacin to treat clarithromycin (CAM)-resistant complex (MAC) lung disease. He was admitted because of fever. Pneumothorax and pleural effusion were present in the right lung, and a new consolidation appeared in the right upper lobe.

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Aims And Objectives: To explore the process by which people with hypersensitivity pneumonitis implement continuous antigen avoidance, alongside the situations that influence this process.

Background: Antigen avoidance is the primary treatment for people with hypersensitivity pneumonitis. However, the best method to support antigen avoidance has not yet been established.

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A 39-year-old woman visited our hospital with complaints of nausea, vomiting, and lower abdominal pain for 2 weeks. Abdominal CT revealed thickening of the transverse colonic wall, dilated bowel, and a metastatic ischemic tumor in the liver (S7). We diagnosed her with obstructive colon cancer, clinical Stage Ⅳa(T, type 2, cT3, N0, M1a[liver]).

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We report 2 cases of neuroendocrine carcinoma(NEC)of colon and rectum with distant metastasis. The treatment of NEC with distant metastasis is based on the treatment of small cell lung cancer, but that is controversial because NEC is relatively rare. Case 1: A 75-year-old man who was admitted for anal pain.

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Calcium-based phosphate binder use is associated with lower risk of osteoporosis in hemodialysis patients.

Sci Rep

January 2021

Department of Nephrology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo, Tokyo, 113-8519, Japan.

Loss of bone mineral density (BMD) is a substantial risk of mortality in addition to fracture in hemodialysis patients. However, the factors affecting BMD are not fully determined. We conducted a single-center, cross-sectional study on 321 maintenance hemodialysis patients who underwent evaluation of femoral neck BMD using dual-energy X-ray absorptiometry from August 1, 2018, to July 31, 2019.

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We report a case of advanced gastric cancer with right gastroepiploic vein tumor thrombus treated using preoperative S-1 plus cisplatin(CDDP)in which pathological complete response was achieved. A 78-year-old man was diagnosed with type 2 gastric cancer located at the greater curvature of the antrum, accompanied by right gastroepiploic vein tumor thrombus. Four courses of S-1 plus CDDP were administered as neoadjuvant chemotherapy.

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A woman in her mid-50's presented to our hospital with jaundice, fatigue, and fever. Jaundice, elevated tumor markers, and lower bile duct stricture suggested malignancy, for which subtotal stomach-preserving pancreaticoduodenectomy was performed. The patient also had annular pancreas as the second part of the duodenum was surrounded by pancreatic parenchyma.

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Article Synopsis
  • * A systematic review and the modified Delphi method were used to create 29 QIs, and we found that measuring adherence to 6 of these QIs was feasible based on data from over 396,000 stroke patients.
  • * The study revealed significant variation in adherence rates among hospitals, indicating that the DPC database can efficiently collect data for evaluating stroke care quality at a lower cost.
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Aim: Hypozincemia is associated with the progression of chronic liver diseases, but it is unknown whether hypozincemia promotes human hepatocarcinogenesis. Our aim is to evaluate the serum zinc levels in liver cirrhosis (LC) patients and clarify the relationship between the serum zinc levels and the development of hepatocellular carcinoma (HCC).

Methods: Cirrhotic patients without HCC (n = 299) were enrolled from 14 medical institutes in Japan as a multicenter prospective study (No.

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We experienced a successful case in which the patient was treated with a combination of operation and transcatheter arterial chemoembolization for a hypervascular tumor of unknown primary origin in the liver; we report this case with a literature review. A 76-year-old man noticed an upper abdominal tumor and he visited our department for detailed examination. Enhanced CT scan showed multiple hypervascular tumors scattered across both lobes of the liver, and the pattern of contrast effect implied that the tumors were primary neuroendocrine tumors or endocrine metastases.

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A 62-year-old man presented with complaints of acute abdominal pain. Abdominal enhanced CT showed free air in the abdominal cavity, a thickened stomach wall accompanied by deep ulcer, and enlarged lymph nodes around the stomach. Emergent surgery was conducted, and a perforation in the upper part of the stomach was found.

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