265 results match your criteria: "Shupyk National Healthcare University of Ukraine[Affiliation]"

Rhabdoid tumor is a rare and aggressive neoplasm that usually occurs in children and is often localized in the central nervous system and kidneys, but can be found in many other sites. In our case report, we describe a tumor that was found on computed tomography in the thoracic region of a 62-year-old male and was successfully surgically resected. The images and descriptions of our findings and the results of the additional immunohistochemical studies allow us to make the final diagnosis.

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Objective: Aim: To assess the level of occupational safety, health and hygiene of healthcare workers in the terms of the COVID-19 pandemic..

Patients And Methods: Materials and Methods: bibliosemantic, bibliographic, analytical, statistical methods as well as a systemic approach have been used in the research.

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Objective: Aim: To conduct a comprehensive analysis and systematization of international standards for biomedical research involving human participants, to identify their key principles and implementation mechanisms, as well as to evaluate their effectiveness in ensuring ethical and legal norms during such research..

Patients And Methods: Materials and Methods: This research employs a diverse array of scientific inquiry methods, encompassing both general scientific approaches and specialized techniques.

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Objective: Aim: To analyze the results of the application of extracorporeal detoxification methods in the treatment of drug poisoning and their complications..

Patients And Methods: Materials and Methods: The studied data of 129 patients aged 18-46 years with severe drug poisoning treated at the Kyiv toxicological center in 2010-2020.

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Objective: . Aim: To analyze the complications during gynecologic surgery procedures and identify possible risk factors associated with this type of surgery in Ukraine.

Patients And Methods: Materials and Methods: We conducted a multicenter, retrospective cohort study in tertiary care hospitals from 12 regions of Ukraine from January, 2021, to December, 2023.

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Objective: Aim: The purpose was to improve the results of treatment of chronic diseases of the lower extremities veins by using endovenous high-frequency electric welding in automatic mode, and to evaluate the obtained results..

Patients And Methods: Materials and methods: The results of treatment of 146 patients with chronic diseases of the lower extremities veins in the period from 2018 to 2023 were analyzed.

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Background: The role of primary healthcare (PHC) during a pandemic varies across European countries. The coronavirus disease 2019 (COVID-19) pandemic has altered the working practices of family medicine doctors and impacted the resilience of healthcare systems.

Objectives: This study aimed to examine European healthcare system responses to the pandemic, focusing on rural and urban differences.

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Objective: Aim: To estimate the frequency of complications during laparoscopic gynecologic surgery for benign diseases in women and identify associated risk factors in Ukraine.

Patients And Methods: Materials and Methods: A multicenter, prospective cohort study was performed in gynecological departments from 10 regional hospitals of Ukraine between January 1, 2020, to December 31, 2022. The study included gynecologic laparoscopies for benign diseases in women performed at these hospitals.

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Prognostic value of magnetic resonance enterography for children with Crohn's disease: A multicenter, multireader study.

Dig Liver Dis

December 2024

Pediatric Hepatology Gastroenterology and Transplantation Unit, ASST Papa Giovanni XXIII, Bergamo, Italy; Pediatric Department, Children's Hospital Vittore Buzzi, University of Milan, Italy. Electronic address:

Background: Paediatric Inflammatory Crohn's MRE Index (PICMI) is a multi-point index of intestinal inflammation (mucosal and transmural) for children with CD. The present study aims to assess whether PICMI at diagnosis may predict the course of CD and to test the inter-reader agreement.

Methods: CD children with a ≥ 1-year follow-up were retrospectively enrolled.

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Article Synopsis
  • - Noncommunicable diseases (NCDs) are a significant health issue, and mitochondrial dysfunction (MD) plays a crucial role in their development and progression, although the causes of MD itself are still not fully understood.
  • - The study emphasizes the need for a comprehensive understanding of how NCD risk factors contribute to MD, proposing a theoretical framework based on extensive research into their relationship.
  • - Conclusions suggest that MD contributes to organ dysfunction and the overlap of various NCDs, calling for preventative measures that focus on identifying and addressing the underlying risk factors, with mitochondria being a key target for treatment.
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  • * In a multicenter study involving 6,740 patients, a 16.5% incidence of SSIs was observed, with the majority being superficial, and many cases detected after hospital discharge; key risk factors included the type of surgical approach and operation duration.
  • * The main pathogens identified were Escherichia coli and Staphylococcus aureus, with significant rates of antibiotic resistance noted, indicating a need for improved preventive measures to reduce complications post-surgery.
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Background: This article aims to examine patient safety in general practice during COVID-19.

Methods: In total, 5489 GP practices from 37 European countries and Israel filled in the online self-reported PRICOV-19 survey between November 2020 and December 2021. The outcome measures include 30 patient safety indicators on structure, process, and outcome.

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Article Synopsis
  • A survey was conducted among 32 senior clinicians across 20 European countries to understand current practices in postnatal prophylaxis (PNP) and infant feeding guidelines.
  • Twenty-three clinicians responded, revealing that all countries use risk stratification for PNP, but methods and regimens widely differ, with zidovudine being the most commonly used drug.
  • There is significant variation in guidelines regarding infant feeding for babies born to HIV-positive parents, highlighting the need for harmonization in policies to minimize HIV transmission and support informed feeding choices.
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  • The study investigated the effectiveness and safety of rituximab for treating childhood steroid-resistant nephrotic syndrome (SRNS) across 28 pediatric nephrology centers globally.
  • Researchers found that children with a longer history of calcineurin inhibitors (CNIs) treatment before rituximab had lower remission rates compared to those with shorter treatment periods.
  • Overall, rituximab showed enhanced remission rates in a portion of SRNS patients, was mostly safe, and achieving complete remission was linked to better kidney survival outcomes.
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Background: Following the 2022 Russian invasion, Ukraine's healthcare system suffered extensive damage, with over 1000 medical facilities destroyed, exacerbating the trauma care crisis. The absence of standardized trauma training left Ukrainian healthcare providers ill-equipped to manage the surge in trauma cases amid conflict. To bridge this gap, we implemented advanced trauma life support (ATLS) courses in Ukraine amid active warfare, aiming to enhance trauma care expertise among healthcare professionals.

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Article Synopsis
  • * Out of 3600 vaginal deliveries, 600 (16.7%) cases of maternal peripartum infections were recorded, predominantly occurring after hospital discharge, with endometritis being the most prevalent infection.
  • * Key risk factors identified for these infections included high body mass index, placenta previa, prolonged rupture of membranes, and various pregnancy-related conditions.
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Article Synopsis
  • Fulminant hepatitis is an uncommon and severe type of acute liver failure (ALF) that leads to rapid liver cell destruction and has a high death rate, often caused by viral infections, alongside existing liver conditions.
  • A 2-year-old patient presented with jaundice and signs of severe infection, being diagnosed with active hepatitis A and Epstein-Barr virus infections, which worsened despite treatment, leading to death on the ninth day of illness.
  • This case is unique due to the simultaneous occurrence of two different viral hepatitis infections against a backdrop of undiagnosed liver disease, highlighting the complexities in diagnosing and treating ALF.
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Background: The optimal TBI dose for ALL patients undergoing allogeneic SCT is still not clearly defined.

Methods: Single-center retrospective analysis of high-risk ALL patients in CR1 treated with 8 Gy (n = 22) or 12 Gy (n = 50) TBI in combination with fludarabine and PTCy. Median patient age in the 8 Gy TBI cohort was 63 (37-79) and 37 (18-56) in the 12 Gy TBI cohort and median follow-up time was 21 months (range 1-92).

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Article Synopsis
  • - The study examines the effectiveness of the Viscoelastic Coagulation Monitor (VCM) as a point-of-care tool to quickly assess blood coagulation after trauma, comparing it to the standard TEG 5000 method to check for correlations and identify coagulopathic conditions in swine models.
  • - Twenty anesthetized swine were subjected to various traumatic injuries, with blood samples taken at multiple time intervals to evaluate the VCM's performance in measuring coagulation changes over time and its relationship with other standard tests and vital parameters.
  • - The results indicated that VCM could effectively detect significant changes in clotting metrics after trauma and did not find significant differences in results whether cartridges were warmed by a heating plate or by being
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Article Synopsis
  • - The study aimed to evaluate how a specialized treatment for peritonitis influenced certain immune proteins in 124 patients, divided into three treatment groups.
  • - Patients receiving cytochrome C alone or with additional compounds (levocarnitine and arginine) showed improved production of important immune proteins, while those not receiving these treatments experienced worsening inflammation markers.
  • - The findings suggest that incorporating cytochrome C and the solution can significantly reduce inflammation in peritonitis patients, helping maintain immune function.
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Objective: Aim: The purpose was to identify the morphological and functional features of the colonic mucus barrier in patients with symptomatic uncomplicated diverticular disease and acute uncomplicated diverticulitis.

Patients And Methods: Materials and Methods: In the research, three groups were formed. Group 1 included fragments of the mucous membrane of the large intestine, which were collected from 12 people during autopsies.

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Objective: Aim: To evaluate the association between adverse pregnancy outcome, assisted reproductive technology (ART) and a previous diagnosis of endometriosis in Ukraine.

Patients And Methods: Materials and Methods: We conducted a multicentre retrospective cohort study was based on infertility surveillance data among women reproductive age from January 1st, 2017 to December 31st, 2021 in Ukraine. The patients from 10 Ukrainian regions who achieved singleton pregnancy by ART were included in this study.

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Aim: This study aims to assess the effectiveness of urothelial cancer treatment in Ukraine, utilizing population-based data from the National Cancer Registry. The primary goal is to evaluate trends and approaches to therapy, with a focus on overall survival rates in patients with urothelial tumors.

Materials And Methods: A retrospective cross-sectional analysis was conducted based on the National Cancer Registry, involving 12 698 patients (2008-2020) with urothelial tumors of the upper urinary tract (UTUC) and bladder cancer (BC) who underwent surgical treatment.

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