2,679 results match your criteria: "Shrewsbury & Telford Hospitals NHS Trust[Affiliation]"

Despite the implementation of latex-free gloves, the issue of natural rubber latex hypersensitivity persists within medical practice, posing challenges for both patients and health care professionals. A comprehensive understanding of the demographic groups susceptible to this condition is essential, along with the establishment of robust perioperative assessment and management protocols aimed at minimising complications and enhancing safety. This article endeavours to delve into the intricacies of perioperative management concerning latex hypersensitivity among patients, while also elucidating its ramifications for health care practitioners.

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This study sought to understand how young adults (age 18-25) with histories of mental health disorders are coping with disrupted transitions to adulthood during the COVID-19 pandemic. A cross-sectional web survey was conducted in March-June 2021 of 967 US young adults with pre-pandemic psychiatric disability to assess their current psychiatric status, interrupted transitions, and associations with social determinants including income, community participation, and social context. Mental health was assessed with the Patient Health Questionnaire (PHQ-9), Generalized Anxiety Disorder Scale (GAD-7), and PTSD Checklist-Civilian Version.

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Purpose Of Review: The purpose of this review is to describe the development and key features of the Prospera™ Spinal Cord Stimulation (SCS) System, as well as the clinical evidence supporting its use. Prospera delivers therapy using a proprietary multiphase stimulation paradigm and is the first SCS system to offer proactive care through automatic, objective, daily, remote device monitoring and remote programming capabilities.

Recent Findings: Results from the recently published BENEFIT-02 trial support the short-term safety and efficacy of multiphase stimulation in patients with chronic pain.

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Purpose Of The Study: Lisfranc is a challenging injury both diagnostically and surgically, with sparse long-term literature evidence of surgical practice. We aim to review our long-term specialist orthopaedic institutional experience of Lisfranc injuries and the surgical management of this complex injury, specifically considering surgical outcomes as per radiological and clinical assessment.

Material And Methods: We present data from a prospectively maintained institutional database, reviewing patients who underwent operative fixation for Lisfranc injury between April 2014 and August 2020.

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Secondary intention healing (SIH) is utilised by various surgical specialities. The formation of granulation tissue is crucial for initiating the healing process, necessitating robust support at this stage. Numerous adjunct therapies are available, with new developments aimed at treating both acute and chronic wounds undergoing SIH.

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Secondary intention healing (SIH) describes wounds healing from the base upwards, without direct closure. This starts with granulation of the wound, followed by re-epithelialisation and contraction. The surgeon and patient need to weigh up advantages and disadvantages of SIH versus other reconstruction methods.

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Background Postoperative delirium (POD) is a common and debilitating complication in elderly hip fracture patients, associated with significant clinical and functional consequences. Early identification of risk factors, such as cognitive impairment and vitamin D deficiency, is essential to mitigate its impact. However, preoperative screening practices are often inconsistent.

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Addressing perinatal mood and anxiety disorders in obstetric settings: results of a cluster randomized controlled trial of two approaches.

Am J Obstet Gynecol MFM

January 2025

Department of Obstetrics and Gynecology, Psychiatry, Pediatrics, Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA (Simas); UMass Memorial Health Department of Obstetrics and Gynecology, Worcester, MA (Simas).

Article Synopsis
  • Mood and anxiety disorders affect one in five perinatal individuals, yet they are often not adequately treated due to various barriers in obstetric practices. To improve this situation, implementation assistance and an e-learning toolkit were developed for obstetric clinicians.
  • The main goal was to assess how these resources impacted the screening and treatment of mood and anxiety disorders compared to usual care by conducting a cluster randomized controlled trial across 13 obstetric practices in the U.S.
  • Results showed that there were no significant differences at baseline in mental health screening documentation among the groups, indicating a need for enhanced strategies in documenting and addressing these disorders effectively.
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Regulation of adverts using brachycephalic breeds.

Vet Rec

January 2025

University of Aberdeen, LAGECDogs, UK Centre for Animal Law, c/o Emstrey House North, Shrewsbury Business Park, Shrewsbury, SY2 6LG.

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Objective: The objective was to describe the pharmacology, efficacy, safety, and recommendations for the use of newly approved preventive agents and vaccines for respiratory syncytial virus (RSV) and discuss their uptake during the 2023 to 2024 RSV season.

Data Sources: A literature search of PubMed was performed (January 2020 to February 2024) with the search terms RSV vaccine, preventive antibody, and RSV prevention. Utilization data were collected from TriNetX using the US Collaborative Network (May 2024) using the terms palivizumab, nirsevimab, and RSV prefusion F protein.

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TREM-1 and TREM-2 as therapeutic targets: clinical challenges and perspectives.

Front Immunol

December 2024

SignaBlok, Inc., Shrewsbury, MA, United States.

TREM-1 and TREM-2 as Therapeutic Targets: Clinical Challenges and Perspectives.

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In 2008 the Postgraduate Medical Education and Training Board (PMETB) Review of Oral and Maxillofacial Surgery (OMFS) recommended that OMFS specialty training should start with second-degree studies. This recommendation has not yet happened. Currently, no OMFS controlled places at medical/dental schools are directly linked to OMFS Specialty Training (ST) posts.

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Introduction: Clavicle fractures are routinely encountered in orthopedic clinical practice and have often been the subject of debate when it comes to optimal treatment. Clavicle fracture surgery has come a long way with excellent pre-contoured superior locking plates available for fixation. This study aimed to evaluate a cohort of patients operated for displaced mid-shaft clavicle fractures by open reduction and internal fixation using superior clavicle locking plates.

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Objectives: The objectives of this study are to determine the functional outcomes and compare them between conservative and surgical management in patients managed for closed-type intra-articular distal end of radius fractures.

Methods: A prospective observational study was done on 150 patients who underwent treatment for closed-type intra-articular distal end of radius fractures. As per Frykman Classification, they were type III.

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Article Synopsis
  • The study focuses on the use of botulinum toxin, particularly onabotulinum toxin A (OTA), for treating migraine and post-traumatic headache (PTH) in military personnel and veterans.
  • The unique challenges faced by this population, including increased pain intensity and longer headache durations due to combat-related trauma, highlight the need for effective headache management strategies.
  • The literature review identified 8 relevant studies, mainly from the U.S., indicating that chronic migraine is the most common diagnosis treated with botulinum toxin, suggesting its effectiveness for preventing such conditions in service members.
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Background Outpatient clinics are increasingly challenged by high patient volumes and rising "did not attend" (DNA) rates, leading to extended wait times and declines in patient satisfaction. Traditional follow-up (FU) models with routinely scheduled appointments contribute to inefficiencies, as stable patients may attend unnecessary visits, thus straining clinic resources. The patient-initiated follow-up (PIFU) model offers an alternative where patients schedule appointments only when necessary.

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Proximal humerus fractures are prevalent in older adults, particularly women, primarily due to osteoporosis and increased fall risk. These fractures often result from low-energy falls in elderly patients, while in younger individuals, they are more likely to occur with high-energy trauma, which may involve additional injuries to soft tissue and neurovascular structures. Proper anatomical understanding, including key structures and blood supply, is crucial for effective management and to prevent complications.

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Introduction: Unplanned out-of-hospital births (UOHBs) are associated with poorer outcomes for babies, especially those born prematurely. The current Newborn Life Support (NLS) course offered by Resuscitation Council UK (RCUK) is not designed to address the challenges associated with birth out of hospital. A new course was developed to address these challenges.

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Outcomes for women with diabetes admitted for labour care to midwifery units in the UK: a national prospective cohort study and survey of practice using the UK Midwifery Study System (UKMidSS).

BMJ Open

December 2024

NIHR Policy Research Unit in Maternal and Neonatal Health and Care, National Perinatal Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK

Article Synopsis
  • The study aimed to analyze outcomes for women with gestational or pre-existing diabetes during labor in midwifery units, comparing them to women without diabetes.
  • Conducted through a national cohort study and practice survey, data was collected from midwifery units in the UK between October 2021 and February 2023.
  • Results indicated that women with diabetes did not have significantly different maternal or neonatal outcomes compared to those without diabetes, suggesting that selected diabetic women can be safely managed in these units.
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Article Synopsis
  • Traditional pain studies have focused on single pain scores, which don't fully capture the complex effects of chronic pain on a person's daily life, mood, and overall quality of life.
  • The study evaluated the Nalu™ Neurostimulation System for treating low-back and leg pain through a 90-day follow-up of patients implanted with this device at 15 pain centers in the US.
  • Results showed that 94% of participants achieved meaningful improvements in at least two patient-reported outcomes, indicating the system's effectiveness in managing chronic pain.
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Article Synopsis
  • The audit aimed to assess and improve the completeness and accuracy of the National Joint Registry (NJR) dataset specifically for elbow arthroplasty surgeries.
  • In a two-phase approach, Phase 1 compared NJR data with NHS England Hospital Episode Statistics (HES), identifying thousands of unmatched and inaccurate records, particularly for radial head arthroplasties (RHAs).
  • Phase 2 involved collaboration among 142 NHS hospitals to correct and update records, resulting in an improved completeness of the NJR dataset from 63% to 93% and accuracy from 94% to 98%.
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Background Intraoperative safety protocols, including proper labelling of syringes, are critical to patient safety in surgical settings. While the Royal Pharmaceutical Society and the Royal College of Anaesthetists provide clear guidelines to prevent medication errors, ensuring consistent compliance with labelling protocols in the fast-paced and complex environment of orthopaedic surgery can still present practical challenges. The absence of proper labelling, combined with the use of multiple fluids such as normal saline, disinfectants, and local anaesthetics, increases the risk of adverse outcomes due to fluid misidentification.

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The case report describes a rare instance of a man in his 70s with periorbital necrotising fasciitis (NF) who underwent bilateral autologous penetrating keratoplasty. NF is an acute infection that can lead to severe complications, including vision loss. The patient presented with severe facial swelling and necrosis of the right eyelid, treated with surgical debridement and antibiotics.

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