Effectiveness of Eupatorium Perfoliatum 30C in Preventing Dengue Fever-A Prospective, Community-Based, Open Label, Parallel Cohort Study in Delhi, India.

Objective:  The study was undertaken to evaluate the protective effect of (EP) 30C on the incidence of dengue fever.

Design:  This study was designed as a prospective, open label, parallel cohort study.

Interventions:  Participants were enrolled in two medicine cohort (MC) communities and one control cohort (CC) community.

Effectiveness of Medhasagar Rasa® in Combating Aging-Associated Mild Neurocognitive Disorder: An Open-Label, Exploratory, Interventional Clinical Trial.

Introduction: With the rising prevalence of neurocognitive disorders (NCDs) among the aging population, particularly in conditions like mild cognitive impairment (MCI), which often precedes dementia, there remains a significant gap in effective pharmacological interventions. This has generated interest in exploring alternative therapies to manage symptoms and enhance cognitive function in the aging population. The primary objective of this study was to evaluate the effect of Medhasagar Rasa® on cognitive functions, daily functioning, and quality of life in participants with aging-associated mild neurocognitive disorder using the Montreal Cognitive Assessment (MoCA) Scale, Ayurvedic Manasabhava Scale, and Brief Cognitive Rating Scale (BCRS).

Ayurvedic management of hydatid cyst of lungs: A case report.

Cystic echinococcosis (CE), which is present in all parts of the world, is caused by the bacterium Echinococcus granulosus. One of the most serious parasitic infectious diseases affecting both humans and animals, CE causes hydatid cysts that can lodge in various host organs, including the liver, lungs, heart, and brain, which can be fatal. Treatment options for cystic echinococcosis are active anthelmintics, surgery, and percutaneous aspiration.

Empowering precision medicine: regenerative AI in breast cancer.

Regenerative AI is transforming breast cancer diagnosis and treatment through enhanced imaging analysis, personalized medicine, drug discovery, and remote patient monitoring. AI algorithms can detect subtle patterns in mammograms and other imaging modalities with high accuracy, potentially leading to earlier diagnoses. In treatment planning, AI integrates patient-specific data to predict individual responses and optimize therapies.

Comparative Evaluation of Different Obturation Techniques for Root Canal Filling of Permanent Teeth: An In-Vitro Study.

Introduction: Achieving success in root canal (RC) therapy relies on three key components: comprehensive cleaning of the canal, efficient disinfection, and proper filling of the canal space. The present study aimed to compare the efficacy of four obturation techniques: single cone (SC), GuttaCore (GC), cold lateral condensation (LC), and C Point system for RC filling of permanent teeth.

Materials And Methods: 76 extracted human mandibular first premolars were divided into four groups, with 19 teeth in each group (group A, obturation with SC technique; group B, obturation with GC; group C, obturation with LC; and group D, obturation with C Point system).

Cross-cultural reliability of Van Rie TB perceived Stigma Scale among TB survivors in North India.

Background: As India progresses towards TB elimination five years ahead of Sustainable Development Goals (SDG), Community-based perceptions of tuberculosis stigma become particularly relevant in the context of TB elimination efforts. This study aims to assess the cross-cultural reliability of 'Community Perspectives Van Rie TB Stigma Scale' which can been used for screening and rapid evaluation of prevalent stigma themes in community.

Methods: A community based cross-sectional study was conducted in North India among 400 TB survivors to assess the cross-cultural reliability of 'Community Perspective Van Rie TB stigma Scale'.

An Improvised External Ventricular Drain Fixation Technique to Avoid Pullout-Related Complications in a Low-Resource Setting: A Descriptive Cross-Sectional Study in a Single Center of Nepal.

Background And Objectives: An external ventricular drain (EVD) placement is a commonly performed life-saving procedure. Its accidental pullout can occur in complex environments, patient care, and positioning, which leads to significant morbidity. The method of EVD fixation and pullout rates is sparsely described in the literature, and there exists a wide variation among the techniques practiced for fixation.

A Randomized Study of Myostaal® Liniment as an Add-On Therapy for Muscle Strengthening in Cases of Knee Osteoarthritis.

Introduction: Knee osteoarthritis (OA) is a prevalent degenerative musculoskeletal condition, affecting approximately 277 million people worldwide, with significant impacts on mobility, especially in women and obese patients, and an increasing incidence among Indians aged 30 to 50 years. The primary objective was to evaluate the knee muscle-strengthening effect of Myostaal® liniment (Solumiks Herbaceuticals Limited, Mumbai, India) as an add-on to physiotherapy for 90 days compared to physiotherapy alone in participants with knee OA. Secondary objectives included assessing changes in the total Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score, WOMAC Subscale scores, Six-Minute Walk Test (6MWT) distance, Single Leg Stance Test (SLST) duration, Visual Analogue Scale (VAS) score, and the number of adverse events from baseline to Day 90 between the two groups.

Evaluation of Various Retention Protocols in Sustaining Treatment Outcomes Following Orthodontic Therapy.

Background: Orthodontic therapy aims at achieving stable treatment outcomes by ensuring retention of corrected tooth positions. Various retention protocols have been proposed, but their efficacy in sustaining treatment outcomes remains unclear.

Materials And Methods: This study evaluated the effectiveness of different retention protocols in maintaining treatment outcomes following orthodontic therapy.

Knowledge and Attitude Regarding Human Milk Banking among Antenatal Mothers Attending Antenatal Clinic.

Background Breast milk is the ideal food that has essential nutrients for the normal growth and development of infants. It contains antibodies that help to protect against many common childhood illnesses. For infants who cannot receive breast milk from their own mothers, due to maternal illness, death, medication, disability, insufficient milk production, allergies, or prematurity, donated breastmilk can become the ideal option.

The Study of Correlation between Symptoms of Gastritis and Endoscopic Biopsy.

Background: Gastritis is a very common disorder that is widely distributed worldwide, representing one of the most prevalent pathological entities in gastroenterology and digestive endoscopy. This study aims to analyse the correlation between the endoscopic findings and the symptoms of gastritis. Upper gastro-intestinal (UGI) endoscopy is a widely used investigation for a variety of UGI symptoms namely dysphagia, dyspepsia, abdominal pain, etc.

Fibromuscular dysplasia: An underrated cause of chronic kidney disease in developing countries: A rare case report.

Renal fibromuscular dysplasia (FMD) is one of the rare cardiovascular conditions affecting the kidneys at very young ages. The exact pathophysiology is still not known and is one of the causes of resistant hypertension in young patients. Severe forms of FMD such as those involving bilateral renal arteries are very few reported in the literature.

Torsemide in Edema Associated with Hepatic Impairment.

Hepatic edema is caused by decreased hepatic protein synthesis, a consequence of decompensated liver cirrhosis. Fluid accumulation occurs when there is an increase in hydrostatic pressure in the hepatic sinusoids and splanchnic capillaries, as well as low albumin. The first-line treatment for cirrhosis-related ascites is an aldosterone antagonist (spironolactone); however, in severe and recurring ascites, a combination of aldosterone antagonists and loop diuretics (torsemide, furosemide, and bumetanide) is preferable.

Unique Pharmacological Properties and Safety Profiles of Loop Diuretics.

Loop diuretics are regarded as essential for the treatment of edematous conditions in heart failure, cirrhosis, and renal disease. The principal mechanism of action involves inhibiting the reabsorption of ions (Na+, 2Cl-, and K+) from the ascending loop of Henle. The pharmacokinetic (PK) and pharmacodynamic (PD) features of the commonly used diuretics (torsemide, furosemide, and bumetanide) influence the selection of diuretics in various disease states and dosing regimens.

Determinants of High HIV Infection Prevalence in Vijayapura, Bagalkot, and Belagavi Districts in Karnataka, India.

Introduction India has the second-highest number of people living with human immunodeficiency virus (PLHIV). Despite the national decline in the prevalence of the human immunodeficiency virus (HIV) from 2000 to 2021, regional variations persist, particularly in the northeastern and southern states. High-risk populations, including female sex workers (FSW), men who have sex with men (MSM), and injecting drug users (IDU), significantly contribute to these dynamics.