187 results match your criteria: "Showa Women's University.[Affiliation]"

: Internet use positively impacts mental health in older adults, with health literacy (HL) playing a key role. While social networks may complement individual HL, the role of neighborhood relationships in this association, particularly by gender, remains unclear. This study examined how the association between HL and Internet use among older adults was modified by neighborhood relationships.

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Distribution status of genetically modified soybeans from the United States and Canada to Japan in 2021 and 2022.

GM Crops Food

December 2025

Division of Analytical Science, Food Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki, Japan.

The number of authorized genetically modified (GM) soybeans has increased worldwide. In Japan, 34 GM soybeans containing single events and their stacked varieties have been approved as food. However, not all approved GM events are commercially cultivated or distributed.

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Aim: This study aimed to develop and validate a Japanese version of the Public Attitudes Toward Epilepsy (PATE-J) Scale to measure attitudes towards epilepsy among the general Japanese population.

Methods: The study employed a cross-sectional design using an online survey of 537 participants from the general public in Japan, with follow-up surveys at 2 weeks and 3 months. The PATE Scale was translated following standard guidelines and validated by conducting confirmatory factor analysis (CFA) on the complete data set to assess the original two-factor structure of the PATE Scale.

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Frailty is a growing public health challenge in Japan's rapidly aging population, where 28.8% are aged ≥ 65. While multicomponent interventions have shown potential in preventing frailty, traditional face-to-face programs face accessibility challenges.

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Background: There are two types of central auditory disorders due to pathology of the bilateral auditory cortices in adult patients: with residual hearing; with total hearing loss. However, long-term changes of hearing acuity over physical development time are unknown.

Objective: The aim of this case report was to illustrate the pathophysiology of auditory changes in a 1 year-3 months old child who was diagnosed with auditory agnosia as a sequel of herpes encephalitis and later developed cortical deafness during a 36-year follow-up.

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Although the safety of genome-edited foods in Japan has been confirmed through pre-submission consultation under the notification process, public perception of safety confirmation methodology has not been investigated to date. Therefore, we created three media to provide information on the safety assurance of genome-edited foods and surveyed the perception of current safety confirmation. In addition, we examined the opinions of researchers in health science on current safety confirmation methods.

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Renal Medulla in Hypertension.

Hypertension

December 2024

Department of Physiology, Medical College of Wisconsin, Milwaukee (A.W.C., M.M.S., T.K., S.S.).

Article Synopsis
  • - Studies indicate that blood flow to the renal medulla is crucial for regulating blood pressure and pressure-natriuresis.
  • - Research in rats suggests that proper medullary blood flow is essential for balancing blood pressure and that reduced blood flow can lead to hypertension.
  • - Enhanced blood flow in the medulla can lower hypertension, and nitric oxide production in this area is vital for protecting against damage caused by various harmful agents.
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Objective: Epilepsy is a neurological disorder characterized by recurrent seizures, exhibiting variance in prevalence and treatment availability across diverse geopolitical contexts and cultural milieus. The stigma associated with epilepsy is a significant global issue affecting the quality of life (QOL) of people with epilepsy (PWE). This study aims to examine the relationship between self-stigma and depressive symptoms in PWE, with a particular emphasis on understanding the manifestations of these across different cultural contexts.

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Article Synopsis
  • - The study aimed to translate the Caveness Questions (CQs), used to assess attitudes toward people with epilepsy, into Japanese (CQs-J) and evaluate its cultural relevance in Japan.
  • - A survey was conducted with 400 participants, focusing on their attitudes towards epilepsy through four specific questions, while also gathering demographic information.
  • - Results revealed varying attitudes based on factors like age, gender, and previous knowledge about epilepsy, highlighting differences in acceptance levels among the participants.
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Article Synopsis
  • The study examined the bioavailability of folate from spinach compared to synthetic folic acid (FA) in mice, revealing that natural folates like those from spinach have significantly different absorption rates.
  • Mice were placed on a folate-deficient diet and then given either synthetic FA or spinach folate to measure how well each source replenished folate levels and affected health markers.
  • Results indicated that spinach folate restored folate levels in the body to about 69% of FA levels and showed promising improvements in plasma homocysteine and chromosomal integrity, suggesting that spinach folate is more bioavailable than previously thought.
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Objective: The aims of this study were to translate the SAPE questionnaire (Scales of the Attitudes toward People with Epilepsy) questionnaire developed in Germany that assesses attitudes toward people with epilepsy (PWE) into Japanese and to examine its reliability and validity.

Methods: We crafted the Japanese version of SAPE (SAPE-J) by drawing upon the original German version. On May 22nd and 23rd, 2023, we surveyed the general public registered with an online research survey service (Cross Marketing Group Inc.

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Introduction: Studies on the relationship between parental and child dietary intakes are limited in Asian populations. Here, we examined parent-child relationships in skin carotenoid levels and vegetable intake in a Japanese community.

Methods: The study participants were 58 children aged 6-15 years and 39 of their guardians (parents) using children's cafeterias.

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In frail older adults (mean age 85 years old), a 3-month supplementation with a low dose (6 g/day) of medium-chain triglycerides (MCTs; C8:0 and C10:0) given at a meal increased muscle mass and function, relative to supplementation with long-chain triglycerides (LCTs), but it decreased fat mass. The reduction in fat mass was partly due to increased postprandial energy expenditure by stimulation of the sympathetic nervous system (SNS). However, the extracellular signals to ameliorate sarcopenia are unclear.

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Cell cycle arrest combined with CDK1 inhibition suppresses genome-wide mutations by activating alternative DNA repair genes during genome editing.

J Biol Chem

September 2024

Division of Biochemistry, National Institute of Health Sciences, Kawasaki, Kanagawa, Japan; Faculty of Food and Health Sciences, Showa Women's University, Tokyo, Japan. Electronic address:

Article Synopsis
  • Cells can repair mutations naturally, but the impact of CRISPR/Cas9-induced DNA breaks on these processes isn't well understood.
  • In this study using TSCE5 cells, researchers inserted target sites for gRNA/Cas9 and I-SceI to disrupt the TK gene, leading to a significant increase in mutations after CRISPR editing.
  • Findings revealed that CRISPR/Cas9 editing led to 859 mutations, including severe variants, and identified new DNA repair pathways activated under specific cell cycle conditions.
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Since the establishment of procedures for the safety assessment of food products that use recombinant DNA technology, the manufacture, import, and sale of genetically modified (GM) foods that have not undergone safety assessment are prohibited under the Food Sanitation Act. Therefore, a performance study to confirm the GM food testing operations of each laboratory is very important to ensure the reliability of the GM food monitoring system. In 2022, GM papaya line PRSV-YK-which has not yet been authorized in Japan-was selected for testing, and a papaya paste and a DNA solution were used as the test samples.

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Skin Carotenoid Levels Are Associated with Demographic Factors, Body Size, and Fruit and Vegetable Intake in the Japanese Population.

Nutrients

July 2024

Department of Nutritional Epidemiology and Shokuiku, National Institute of Biomedical Innovation, Health and Nutrition, Kento Innovation Park, NK Building, 3-17 Senrioka Shinmachi, Settsu-shi 566-0002, Osaka, Japan.

This study aimed to determine the association between demographic factors, body size, and fruit and vegetable intake in the general population, focusing on individuals with both low and high skin carotenoid levels. This cross-sectional study was conducted during the 14th National Convention on the Promotion of Food and Nutrition Education (2019) in Yamanashi, Japan (a rural area) and the Open House 2019 at the National Institute of Biomedical Innovation, Health, and Nutrition in Tokyo, Japan (an urban area). Skin carotenoid measurements were conducted, and the participants were asked to fill out a self-administered questionnaire.

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As loneliness is a risk factor for mental and physical health problems in various age groups, this study aimed to explore the impact of the intergenerational (food and nutrition education) program (IGSP) on loneliness in a Japanese community. This single-arm intervention study conducted between 2022 and 2023 included children (n = 21), guardians (n = 16), university students (n = 3), and older adults (n = 6). The IGSP was a one-day program that included participants making and eating their own bread, butter, and sorbet.

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Meals comprising a staple grain, a main, and side dishes (SMS meals) promote good dietary intake, yet limited studies have examined their multifactorial relationship with dietary intake. We investigated how demographic characteristics, lifestyle, and dietary habits affect the relationship between SMS meal frequency and nutrient intake adequacy. This cross-sectional study analyzed survey data from 331 Japanese adults (208 men and 123 women) aged 30-69 years in February 2019.

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Peripheral nerve injury (PNI) induces debilitating neuropathic pain symptoms, such as tactile allodynia. Accumulating evidence suggests that the expression levels of various transcripts and proteins are drastically changed after PNI. Recent lipidome analysis demonstrates increased levels of diverse lipids in chronic pain conditions.

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Impact of Shifting From Office Work to Telework on Workers' Physical Health: A Longitudinal Study.

J Occup Environ Med

May 2024

From the Department of Food Science and Nutrition, Showa Women's University, Tokyo, Japan (R.H.); Department of Preventive Medicine and Public Health, Tokyo Medical University, Tokyo, Japan (R.H., H.K., M.M., S.I.); and Daito Trust Construction Co, Ltd, Tokyo, Japan (Y.N.).

Objective: The aim of the study is to clarify the longitudinal association between teleworking and physical health changes of Japanese workers before and during the COVID-19 pandemic.

Methods: Participants were in a certain company who received mandatory health examinations in 2019 and 2020. In June 2020, the participants were asked about frequency of teleworking, which was introduced owing to the COVID-19.

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Background: In Japan, routine administration to one-year-old children of two-dose immunization for varicella was introduced in October 2014. Object The object of this study was to report outbreaks of varicella under routine immunization at a nursery school and in its surrounding area using data of surrounding areas from the (Nursery) School Absenteeism Surveillance System. Then, we measured the effectiveness of routine two-dose immunization for varicella to onset.

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We examined the effect of sleep and resilience on stress responses in female Japanese university students during the COVID-19 pandemic. Sleep was measured using the Japanese version of the Pittsburgh Sleep Quality Index (PSQI-J), stress response was evaluated using the Stress Response Scale-18 (SRS-18), and resilience using the Resilience Scale for Students (RS-S). Multiple regression analysis showed that approximately 40% of the SRS-18 score could be explained by PSQI-J score and RS-S score.

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The analysis of ascorbic acid using the 2,6-dichloroindophenol (DCIP) titration method is a well-established technique, but requires the skilled handling of a burette for accurate measurements. In the present study, we propose a modified DCIP titrimetric method that replaces the burette with a dropper and employs an electronic balance to measure the titrated amount by weight. The dropper used can be flexibly selected, allowing for a wide range of drop sizes, from large to very small.

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Promoting subjective well-being is a crucial challenge in aging societies. In 2022, we launched a community-based intervention trial (the Chofu-Digital-Choju Movement). This initiative centered on fostering in-person and online social connections to enhance the subjective well-being of older adults.

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We conducted a systematic review of conference papers in social psychology at two large psychology conferences in Japan: the Japanese Psychological Association and the Japanese Society for Social Psychology. The conference papers were effectively not subjected to peer review; hence, they were suitable for testing if psychologists selectively reported statistically significant findings without pressure from journal editors and reviewers. We investigated the distributions of -values converted from the -values reported in the articles presented at the 2013 and 2018 conferences.

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