Longterm retention rate and risk factor for discontinuation due to insufficient efficacy and adverse events in Japanese patients with rheumatoid arthritis receiving etanercept therapy.

Objective: Assessing retention rate and risk factor for drug discontinuation is important for drug evaluation. We examined a 3-year retention rate and the risk factor for discontinuation due to insufficient efficacy (IE) and adverse events (AE) in Japanese patients with rheumatoid arthritis (RA) who are receiving etanercept (ETN).

Methods: Data were collected from 588 patients treated with ETN as a first biologic from the Tsurumai Biologics Communication Registry.

Successful embolization therapy for bleeding from jejunal varices after choledochojejunostomy: report of a case.

We report a case of successful embolization of jejunal varices that were the cause of massive gastrointestinal bleeding from a choledochojejunostomy site, resulting from obstruction of the extrahepatic portal vein. A 42-year-old man who had undergone choledochojejunostomy for intrahepatic and choledochal stones was readmitted after he started passing massive dark bloody stools. Gastrointestinal endoscopic examination and angiography could not identify the source of bleeding.

Plasma lipase, C-peptide reactivity and human pancreatic polypeptide responses after ingestion of elemental diet in patients with chronic pancreatitis.

Plasma lipase, C-peptide reactivity (CPR) and human pancreatic polypeptide (HPP) responses after ingestion of elemental diet were studied in 27 patients with chronic pancreatitis. These subjects were classified into 3 groups according to ERP findings; minimum or mild (MIP, n = 17), moderate (MOP, n = 6) and advanced (ADP, n = 4). Basal plasma lipase levels in the MIP and MOP patients were significantly higher than that in the controls (P < 0.

Sarcoma associated with pregnancy.

A case is reported of sarcoma associated with pregnancy in which the patient underwent a cesarean section with myomectomy and was delivered of a living infant. A pathologic examination indicated sarcoma.

A case report of destructive mole after uterine rupture.

We describe a patient 17 weeks pregnant whose complaints were diagnosed as acute abdomen. The patient underwent a total abdominal hysterectomy and uterine rupture was found with, surprisingly, a live fetus. Pathologic examination indicated destructive mole.

[Percutaneous nephroureterolithotomy in two city hospitals: review of 102 cases].

The authors experienced 102 cases of percutaneous nephroureterolithotomy (PNL) in the urological clinic at two city hospitals between May, 1984, and July, 1986. Percutaneous access for renal pelvis was performed under interventional ultrasound and the disintegration of stones was mainly performed by an electric drill system. Stones were successfully removed in all the cases, although residual stones were recognized in 16 cases (15.