A case of acute posterior multifocal placoid pigment epitheliopathy demonstrating vogt-koyanagi-harada disease-like optical coherence tomography findings in the acute stage.

Purpose: We report a case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE), which was difficult to differentiate from posterior pole-type Vogt-Koyanagi-Harada (VKH) disease because the lesions were mainly located in the macula bilaterally.

Case Report: A 33-year-old man presented with rapid bilateral loss of vision. Fundoscopy revealed yellow-white subretinal lesions in the posterior pole of both eyes.

Choroidal folds in acute-stage vogt-koyanagi-harada disease patients with relatively short axial length.

Purpose: To report 2 cases of Vogt-Koyanagi-Harada disease accompanied by remarkable choroidal folds in the acute stage. The early indicator of recurrence in these 2 cases was the identification of choroidal folds by spectral-domain optical coherence tomography (SD-OCT).

Case Reports: A 68-year-old woman (Case 1) presented with visual loss in both eyes.

Higher concentration of transforming growth factor-beta in aqueous humor of glaucomatous eyes and diabetic eyes.

Purpose: Diabetic retinopathy and glaucoma are the primary causes of acquired blindness. Cytokines including transforming growth factor (TGF)-beta may be involved in these diseases. We therefore collected aqueous humor samples from patients with glaucoma and/or diabetes who were undergoing surgery, and determined the concentration of TGF-beta.

Age and increased incidence of "forward bowing" of the iris in normal eyes.

Purpose And Methods: The incidence of forward bowing of the iris, width of the iridocorneal angle, and distance between the apex of the angle and the scleral spur were studied using high-frequency (50 MHz) ultrasound B-scan images in 90 normal eyes from Japanese volunteers.

Results: The incidence of forward bowing of the iris, defined as a 120-micron anterior shifting of the posterior profile of the iris, increased from 0% in subjects under 31 years old to 50% in subjects 71 years of age and older. The iridocorneal angle was significantly narrower and the distance between the apex of the angle and the scleral spur was significantly less in eyes with forward bowing.