88 results match your criteria: "Shijonawate-Gakuen University[Affiliation]"

The skin's moisturizing function declines with age, resulting in skin dryness in around 40% of older people. Various lifestyle habits may affect the skin moisturizing function, however it is not clear which ones are particularly relevant. A cross-sectional study was conducted between September and December 2023, involving individuals aged 65 years and over.

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  • Researchers created a new Alzheimer’s disease (AD) model mouse using human tau protein to better understand microglial states related to tau pathology, which hasn't been thoroughly studied yet.
  • The study found that microglia associated with disease increased after tau accumulation, suggesting a shift from age-related microglia to a disease-associated profile in the brains of these model mice.
  • Advanced techniques like single-nucleus RNA sequencing and spatial transcriptomics were employed to highlight how tau propagation affects microglial behavior, paving the way for deeper insights into tau-related changes in the AD brain.
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This study aimed to investigate whether the cerebellum contributes to contraction-induced facilitation (CIF) of contralateral corticospinal excitability. To this end, repetitive cerebellar transcranial magnetic stimulation (TMS) was used to test whether it modulates CIF. Overall, 20 healthy young individuals participated in the study.

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  • This prospective cohort study investigated factors that lead to Sever's disease in junior gymnasts, analyzing 74 limbs from 37 athletes over six months.
  • The evaluation included demographic data, flexibility, foot alignment, trunk function, and balance tests to assess the incidence of the disease.
  • Findings indicated that gymnasts with Sever's disease had lower arch height ratios and balance scores, suggesting that preventive measures like arch supports and balance training could be beneficial.
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Background: This systematic review and meta-analysis aimed to assess the effectiveness of non-invasive brain stimulation (NIBS), including repetitive transcranial magnetic stimulation (rTMS) and transcranial electrical stimulation (tES), as a neurological intervention for degenerative cerebellar ataxia (DCA) based on preregistration (PROSPERO: CRD42023379192).

Objective: We aimed to explore clinical outcomes and examine the parameters associated with NIBS efficacy in DCA patients.

Methods: The PubMed, Cochrane Library, CHINAL, and PEDro databases were searched for relevant randomized controlled trials (RCTs).

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Tests to detect mild cognitive impairment (MCI) should have high sensitivity and accuracy. Previously, we reported on a cognitive composition test (CCT) that we developed to detect MCI. In this study, we compared gaze behavior parameters, namely, gaze fixation duration and gaze-shift frequency, during the CCT in participants with MCI and healthy controls (HC) to determine whether these parameters would accurately detect MCI in older adults.

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The sternoclavicular joint (SCJ) functions as the basal joint of the entire upper limb and must move in the proper pattern for normal scapular motion. Afferent sensations from joints, such as proprioception and pain sensation, are important for maintaining the proper motion and condition of joints. Detailed anatomical data are useful for discussing injuries or surgeries that impair the afferent nerve to the SCJ.

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This study aimed to evaluate the efficacy and safety of navigation-guided repetitive transcranial magnetic stimulation (rTMS) over the primary motor cortex in patients with neuropathic pain in the upper limb. This randomized, blinded, sham-controlled, parallel trial included a rTMS protocol (10-Hz, 2000 pulses/session) consisting of five daily sessions, followed by one session per week for the next seven weeks. Pain intensity, as well as pain-related disability, quality of life, and psychological status, were assessed.

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Background: The skin is an important organ of the human body and has moisturizing and barrier functions. Factors such as sunlight and lifestyle significantly affect these skin functions, with sunlight being extremely damaging. The effects of lifestyle habits such as smoking, diet, and sleep have been studied extensively.

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The purpose of this study was to compare the acceleration and surface electromyography (EMG) of the lower extremity and trunk muscles during straight-leg raising (SLR) in patients with incomplete cervical cord injury according to their levels of walking independence. Twenty-four patients were measured acceleration and EMG during SLR held for 10 s. Data were analyzed separately for the dominant and nondominant sides and compared between the nonindependent (NI) and independent (ID) groups based on their levels of walking independence.

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  • Movement disorders from neurological conditions like stroke, cerebral palsy, MS, PD, and SCD can severely affect daily living activities.
  • These disorders disrupt normal movement and coordination, impacting a person's ability to perform tasks such as walking, dressing, or eating.
  • Effective management and treatment options are essential for improving quality of life for individuals with these conditions.
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Among lifestyle habits, the effect of exercise on skin moisturizing function has not been studied. Therefore, we aimed to clarify the effect of regular exercise on skin moisturizing function. The participants were 30-64 years old with no history of skin diseases and no exercise habits at the start of the study.

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Fear-related visual stimuli do not promote internal focus of attention in older adults.

Gait Posture

February 2024

Faculty of Rehabilitation, Shijonawate Gakuen University, 5-11-10 Houjo, Daito, Osaka 574-0011, Japan.

Background: The influence of internal focus (IF) on postural balance needs to be determined when assessing fall risk in older adults. Moreover, the mechanism through which IF is triggered should be elucidated.

Research Question: Does fear unrelated to threats to postural balance modulate IF during postural control?

Methods: The participants were 16 community-dwelling older adults.

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Background: Left ventricular assist device (LVAD) implantation is among the most effective treatment options for patients with severe heart failure. Although previous studies have examined the factors related to peak oxygen uptake (peak VO ), they were limited by the few patients involved and their focus on medical and physical functions. Therefore, this study comprehensively examined the factors associated with peak VO , which is an important prognostic factor in patients with implantable LVADs.

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  • The study investigated the relationship between gaze fixation on the eyes and mouth in children at age 6 and the severity of autism spectrum disorder (ASD) symptoms and functioning.
  • Using an eye-tracking device, the research examined 742 participants and measured their gaze fixation during social interactions, linking these metrics to ASD outcomes.
  • Results indicated that higher gaze fixation on the eyes correlated with a lower likelihood of severe ASD symptoms, while gaze fixation on the mouth was linked to better socialization skills, emphasizing the importance of eye contact in understanding ASD.
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Aim: To examine how supporters working at after-school daycare centres, who are involved in the lives of children with profound intellectual and multiple disabilities in the community, pay attention to the sensory characteristics of these children and provide support.

Design: A qualitative descriptive design.

Methods: Data were collected through semi-structured interviews with 20 supporters in after-school daycare centres.

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  • The study explored how inhibitory cortical excitability and motor control are affected in individuals with degenerative cerebellar ataxia (DCA) compared to healthy individuals during ballistic-targeting movements.
  • Sixteen participants were involved, with findings showing that individuals with DCA had a significantly longer cortical silent period (cSP) but no correlation between cSP and ataxia severity.
  • The increased inhibitory activity in the brain may hinder motor control in DCA patients, and the study highlights the need for more research on motor control issues related to DCA, despite the small sample size.
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  • The study investigates the potential of non-invasive brain stimulation (NIBS) techniques to improve symptoms in patients with degenerative cerebellar ataxia (DCA), a condition characterized by movement disorders and balance issues.
  • A systematic review and meta-analysis will be conducted, focusing on randomized controlled trials that assess NIBS effects on clinical outcomes like cerebellar ataxia and gait ability.
  • The review aims to provide evidence that could inform clinical practices and enhance treatment options for individuals suffering from DCA.
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The Fugl-Meyer Assessment (FMA) has been used as a functional assessment of upper-limb function in stroke patients. This study aimed to create a more objective and standardized evaluation based on an FMA of the upper-limb items. A total of 30 first-ever stroke patients (65.

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Since individuals with cerebellar lesions often exhibit hypotonia, the cerebellum may contribute to the regulation of muscle tone and spinal motoneuron pool excitability. Neurophysiological methods using transcranial magnetic stimulation (TMS) of the cerebellum have been recently proposed for testing the role of the cerebellum in spinal excitability. Under specific conditions, single-pulse TMS administered to the cerebellar hemisphere or vermis elicits a long-latency motor response in the upper or lower limb muscles and facilitates the H-reflex of the soleus muscle, indicating increased excitability of the spinal motoneuron pool.

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Objective: This study aimed to investigate whether longitudinal changes in exercise capacity in patients with acute myocardial infarction (AMI) differ by sex and clarified what contributed to these differences.

Methods: We retrospectively examined the differences in each variable between men and women in 156 patients with AMI (mean age: 65 ± 12 years; 82.0% male) who participated in a 3-month cardiac rehabilitation (CR) program and could be followed-up for exercise capacity 12-months after AMI onset.

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Mild cognitive impairment (MCI) is the preliminary stage of dementia, which is a serious social problem worldwide. This study aimed to investigate whether the Cognitive Composition Test (CCT) is effective for the early diagnosis of MCI. A total of 104 older adults underwent the Montreal Cognitive Assessment (MoCA), the Mini-Mental State Examination (MMSE), the Trail Making Test Parts A (TMT-A) and B (TMT-B), and our newly prototyped cognitive composition test (CCT).

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