1,011 results match your criteria: "Shifa International Hospital[Affiliation]"

Purpose: This systematic review aimed to collate and synthesize the available literature on the abscopal effect in Glioblastoma multiforme (GBM) neoplasms, focusing on the reported biochemical mechanisms driving the abscopal effect.

Methods: A systematic search was conducted in PubMed, Cochrane Database of Systematic Reviews, and Epistemonikos from inception to May 1, 2023. Studies exploring the abscopal effect in GBM were included.

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Objectives: To assess the incidence, causative pathogens, and impact of external ventricular drain-related infection on disease prognosis.

Methods: The observational, cross-sectional study was conducted from September 2022 to March 2023 after obtaining approval from the ethics review board of Shifa International Hospital, Islamabad, Pakistan, and comprised patients having no prior cerebrospinal fluid infection. The patients underwent external ventricular drain administration as part of their treatment.

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  • Dyslipidemia and cardiovascular issues are common in Pakistan, driven by factors like poor education, poverty, and unhealthy diets; the study aimed to review international guidelines and create tailored nutritional recommendations for the local context.
  • A systematic review of 23 guidelines was conducted, assessing their quality and extracting dietary patterns that cater to managing dyslipidemia, linked with local food sources and economic conditions.
  • The research emphasizes that dietary changes are critical for tackling dyslipidemia in Pakistan, advocating for collaboration between healthcare professionals and dietitians to provide effective, culturally appropriate dietary advice.
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POSTPARTUM PSYCHIATRIC DISORDERS - A NEGLECTED AREA IN PAKISTAN.

J Ayub Med Coll Abbottabad

January 2024

Department of Clinical Psychology, Shifa Tameer e Millat University, Shifa International Hospital, Islamabad-Pakistan.

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  • Obesity is a chronic disease with effective treatment options through bariatric surgeries, specifically Roux-en-Y gastric bypass (RYGB) and one-anastomosis gastric bypass (OAGB), both of which can lead to malnutrition risks.
  • OAGB results in greater weight loss and diabetes remission but has a higher incidence of folate deficiency compared to RYGB, with 30.8% of OAGB patients experiencing this compared to 8.0% in the RYGB group.
  • The study found no significant differences in deficiencies of vitamin B12, vitamin D, or ferritin between the two surgery groups despite varying outcomes in folate levels post-surgery.
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  • - Extra-skeletal Ewing sarcoma (EES) is a rare but aggressive tumor that affects soft tissue and is part of the primitive neuroectodermal tumors family, with only about 30 documented cases.
  • - A 20-year-old female patient experienced symptoms like shortness of breath and chest pain, leading to the discovery of a soft tissue mass that was eventually diagnosed as Ewing sarcoma through biopsy.
  • - Early detection and a multidisciplinary treatment approach, including surgical resection and chemotherapy, are crucial for improving patient outcomes, as EES often presents with non-specific symptoms and has a poor prognosis.
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  • - A 48-year-old woman experienced severe lower back pain radiating to her right leg, diagnosed with an intradural neuroenteric cyst at the L2 level via MRI.
  • - The cyst was T2 hyperintense and T1 isointense, and histological analysis confirmed it was a well-defined ovoid neuroenteric cyst, appearing brighter than cerebrospinal fluid.
  • - Following cyst removal and L2 laminectomy, the patient experienced significant pain relief and had completely recovered by a two-week follow-up, highlighting the effectiveness of MRI and surgical intervention.
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  • Laparoscopic sleeve gastrectomy (LSG) is a popular bariatric surgery, and a study was conducted to examine the histopathology of specimens from 538 LSG cases over ten years at Shifa International Hospital in Pakistan.
  • The majority of cases showed gastritis (80.5%), with 26% of specimens exhibiting infection, while there were few other notable findings like intestinal metaplasia and two tumors linked to gastritis.
  • There were no significant differences in the prevalence of gastritis or infection based on age or gender, highlighting the common occurrence of gastric changes in morbidly obese patients undergoing LSG.
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  • - New guidelines suggest a 5-year survival rate of at least 60% for hepatocellular carcinoma (HCC) patients receiving living donor liver transplants, and this study looks at outcomes for those who meet expanded criteria.
  • - The study included 208 patients, reporting 5-year and 10-year survival rates of 67% and 61% respectively, with a recurrence risk of about 20.5% at 5 years and 22.5% at 10 years; larger tumors and higher AFP levels correlated with increased recurrence risk.
  • - Patients classified as low-risk for HCC based on tumor size and AFP levels had a 5-year recurrence risk similar to those meeting the traditional Milan criteria,
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  • A 45-year-old male presented with abdominal pain, loose stools with intermittent melena, and joint pains, having experienced similar issues in the past relieved by steroids.
  • Initial tests for infection and autoimmune disorders were inconclusive, while renal function tests indicated acute kidney injury, leading to further investigation.
  • A positive c-ANCA test ultimately confirmed a diagnosis of granulomatosis with polyangiitis (GPA), and the patient showed improvement after starting on steroid and immunomodulator treatment.
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  • - Occupational contact dermatitis (OCD) is a skin condition caused by repeated exposure to hand sanitizers and chemicals, leading to inflammation, particularly affecting the hands in occupational settings.
  • - An umbrella review following PRISMA 2020 standards evaluated literature on OCD related to COVID-19, highlighting a systematic search that yielded 11 papers after applying strict inclusion criteria.
  • - The review anticipates a rise in dermatitis cases due to face mask use among healthcare workers and emphasizes the need for more research on the prevalence and treatments for this condition.
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  • - Sickle cell disease (SCD) is a hereditary blood disorder that leads to chronic pain, anemia, and various health complications, but advancements in treatments have improved patient outcomes over time.
  • - Despite progress, challenges like limited access to stem cell transplants and complications from current therapies highlight the need for ongoing research in SCD treatments.
  • - The recent FDA approval of Casgevy, a CRISPR/Cas9-based gene therapy, represents a significant step in SCD treatment, with the review focusing on its potential effectiveness and safety compared to traditional methods, emphasizing the need for long-term research.
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