4 results match your criteria: "Shenzhen Second People's Hospital. Electronic address: gelinxu@nju.edu.cn.[Affiliation]"
Post-procedural Plasma D-dimer Level May Predict Futile Recanalization in Stroke Patients with Endovascular Treatment.
J Stroke Cerebrovasc Dis
January 2025
Department of Neurology, First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital. Electronic address:
Objective: High D-dimer levels may increase the likelihood of unfavorable clinical outcomes in patients with acute ischemic stroke. However, the impacts of serum D-dimer levels on outcomes of reperfusion treatment in patients with acute ischemic stroke have not been evaluated. This study aims to assess a possible relationship between serum D-dimer and functional outcomes in stroke patients with endovascular treatment (EVT).
View Article and Find Full Text PDFThe association between fatigue and cardiometabolic diseases: Insights from the UK biobank study.
J Affect Disord
February 2025
Department of Neurology, Centre for Leading Medicine and Advanced Technologies of IHM, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China. Electronic address:
Article Synopsis
- Cardiometabolic diseases (CMD) are significant health issues, and fatigue may be both a risk factor and a consequence, with unclear relationships needing further investigation.
- The study used data from the UK biobank and employed genetic methods to explore causal relationships, finding that fatigue significantly increases the risk of stroke, Type 2 diabetes (T2D), coronary artery disease (CAD), and heart failure (HF).
- Results suggest a bidirectional relationship where fatigue can contribute to CMD, and T2D can increase fatigue, highlighting the importance of addressing fatigue in cardiometabolic health management.
Microglial repopulation induced by PLX3397 protects against ischemic brain injury by suppressing neuroinflammation in aged mice.
Int Immunopharmacol
September 2024
Department of Neurology, Shenzhen Institute of Translational Medicine, First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, School of Biomedical Engineering, Shenzhen University Medical School, Shenzhen 518060, China. Electronic address:
As the resident immune cells in the central nervous system, microglia exhibit a 'sensitized' or 'primed' phenotype with dystrophic morphology and dysregulated functions in aged brains. Although studies have demonstrated the inflammatory profile of aged microglia in several neurological diseases, this issue is largely uncertain in stroke. Consequently, this study investigated the effects of primed and repopulated microglia on post-ischemic brain injury in aged mice.
View Article and Find Full Text PDFAssociation between dietary antioxidant capacity and atherosclerotic carotid stenosis in patients with ischemic stroke.
J Stroke Cerebrovasc Dis
August 2023
Department of Neurology, Affiliated Jinling Hospital, Medical School, Nanjing University, Nanjing, China; Department of Neurology, Shenzhen Second People's Hospital, Shenzhen, China; First Affiliated Hospital of Shenzhen University, Shenzhen, China. Electronic address:
Background And Purpose: The aim of this study was to evaluate the relationship between dietary total antioxidant capacity (DTAC) and atherosclerotic carotid stenosis in patients with ischemic stroke.
Methods: Patients with acute ischemic stroke were consecutively enrolled. Daily food consumption was estimated by a semi-quantitative food frequency questionnaire (FFQ).