Breaking the Ice: Hofmeister Effect-Inspired Hydrogen Bond Network Reconstruction in Hydrogel Electrolytes for High-Performance Zinc-Ion Batteries.

Gel electrolytes have emerged as a promising solution for enhancing the performance of zinc-ion batteries (ZIBs), particularly in flexible devices. However, they face challenges such as low-temperature inefficiency, constrained ionic conductivity, and poor mechanical strength. To address these issues, this study presents a novel PAMCD gel electrolyte with tunable freezing point and mechanical properties for ZIBs, blending the high ionic conductivity of polyacrylamide with the anion interaction capability of β-cyclodextrin.

Effect of salt stress on different tiller positions in rice and the regulatory effect of prohexadione calcium.

Soil salinization has resulted in a significant decrease in crop yields, particularly affecting the production of crops like rice ( L.). Prohexadione calcium (Pro-Ca) can enhance crop resilience against failure by managing plant height.

The application of machine learning algorithms for predicting length of stay before and during the COVID-19 pandemic: evidence from Wuhan-area hospitals.

Objective: The COVID-19 pandemic has placed unprecedented strain on healthcare systems, mainly due to the highly variable and challenging to predict patient length of stay (LOS). This study aims to identify the primary factors impacting LOS for patients before and during the COVID-19 pandemic.

Methods: This study collected electronic medical record data from Zhongnan Hospital of Wuhan University.

Circulating Tumor Cells Culture: Methods, Challenges, and Clinical Applications.

Circulating tumor cells (CTCs) play a pivotal role in cancer metastasis and hold considerable potential for clinical diagnosis, therapeutic monitoring, and prognostic evaluation. Nevertheless, the limited quantity of CTCs in liquid biopsy samples poses challenges for comprehensive downstream analysis. In vitro culture of CTCs can effectively address the issue of insufficient CTC numbers.

Human microbiome-derived peptide affects the development of experimental autoimmune encephalomyelitis via molecular mimicry.

Background: Gut commensal microbiota has been identified as a potential environmental risk factor for multiple sclerosis (MS), and numerous studies have linked the commensal microorganism with the onset of MS. However, little is known about the mechanisms underlying the gut microbiome and host-immune system interaction.

Methods: We employed bioinformatics methodologies to identify human microbial-derived peptides by analyzing their similarity to the MHC II-TCR binding patterns of self-antigens.

Nervonic acid alleviates radiation-induced early phase lung inflammation by targeting macrophages activation in mice.

Background: Patients receiving chest radiation therapy, or exposed to high radiation levels due to accidental nuclear leakage are at risk of radiation-induced lung injury (RILI). In innate immunity, macrophages not only exhibit certain radiation tolerance but also play an important regulatory role in the whole pathological process. Nervonic acid (NA), a long-chain unsaturated fatty acid found in nerve tissue, plays a pivotal role in maintaining normal tissue growth and repair.

Focused Electric Field Technology: A Novel Myoelectrical Stimulation Technology for Noninvasive Aging Muscle Rejuvenation.

Background: Myoelectrical stimulation improves muscle function and reduces muscle atrophy and aging. However, research on the mechanism underlying its cosmetic effect remains limited.

Aims: The aim of this study was to evaluate the cosmetic effects of the myoelectrical stimulation provided by the wearable intelligent flexible beauty device and its focused electric field technology (FEFT) on facial skin and muscle rejuvenation.

Fucoxanthin ameliorates ulcerative colitis by maintaining the epithelial barrier via blocking JAK2/STAT3 signaling pathway.

Background: The clinical efficacies of Ulcerative colitis (UC) are far from satisfactory. Fucoxanthin (FUC) is a marine carotenoid that is abundant in seaweed and microalgae. It has been reported that FUC can possess anti-inflammatory and antioxidant.

Chlorpyrifos Influences Tadpole Development by Disrupting Thyroid Hormone Signaling Pathways.

Chlorpyrifos (CPF) is a widely used organophosphate insecticide with serious toxicological effects on aquatic animals. Although extensively studied for neurotoxicity and endocrine disruption, its stage-specific effects on amphibian metamorphosis and receptor-level interactions remain unclear. This study investigated the effects of CPF on metamorphosis at environmentally relevant concentrations (1.

A novel dual-step transfer framework based on domain selection and feature alignment for motor imagery decoding.

In brain-computer interfaces (BCIs) based on motor imagery (MI), reducing calibration time is gradually becoming an urgent issue in practical applications. Recently, transfer learning (TL) has demonstrated its effectiveness in reducing calibration time in MI-BCI. However, the different data distribution of subjects greatly affects the application effect of TL in MI-BCI.

Functional traits and adaptation of lake microbiomes on the Tibetan Plateau.

Background: Tibetan Plateau is credited as the "Third Pole" after the Arctic and the Antarctic, and lakes there represent a pristine habitat ideal for studying microbial processes under climate change.

Results: Here, we collected 169 samples from 54 lakes including those from the central Tibetan region that was underrepresented previously, grouped them to freshwater, brackish, and saline lakes, and generated a genome atlas of the Tibetan Plateau Lake Microbiome. This genomic atlas comprises 8271 metagenome-assembled genomes featured by having significant phylogenetic and functional novelty.

Large Scale Synthesis of Red-Emitting Quantum Dots for Efficient and Stable Light-Emitting Diodes.

It is known that large-scale synthesis of emitters affords colloidal quantum dot (CQD) materials with a great opportunity toward the mass production of quantum dot light-emitting diodes (QLEDs) based commercial electronic products. Herein, an unprecedented example of scalable CQD (> 0.5 kilogram) is achieved by using a core/shell structure of CdZnSe/ZnSeS/CdZnS, in which CdZnSe, ZnSeS, and CdZnS alloys are used as the inner core, transition layer and outermost shell, respectively.

Chitooligosaccharide application enhanced the growth and phytoremediation efficiency of industrial hemp in Cd-contaminated soils.

Hemp has been widely used for cadmium (Cd) remediation. However, its remediation efficiency needs to be improved. Chitooligosaccharides can enhance plant resistance and growth; however, their effects on hemp for Cd-remediation remain unclear.

Rapid and high accuracy identification of culture medium by CNN of Raman spectra.

Culture media are widely used for biological research and production. It is essential for the growth of microorganisms, cells, or tissues. It includes complex components like carbohydrates, proteins, vitamins, and minerals.

A High-Throughput and Logarithm-Serial-Dilution Microfluidic Chip for Combinational Drug Screening on Tumor Organoids.

Tumor organoids are biological models for studying precision medicine. Microfluidic technology offers significant benefits for high throughput drug screening using tumor organoids. However, the range of concentrations achievable with traditional linear gradient generators in microfluidics is restricted, generating logarithmic drug concentration gradients by adjusting the channel ratio in the chip is confined to single-drug dilution chips, significantly restricting the application of microfluidics in drug screening.

Regulating Strain and Suppressing Defect States Through Polymer Ionization and Chemical Chelation for Efficient Inverted Flexible Perovskite Solar Cells.

Flexible perovskite solar cells (FPSCs) have great promise for applications in wearable technology and space photovoltaics. However, the unpredictable crystallization of perovskite on flexible substrates results in significantly lower efficiency and mechanical durability than industry standards. A strategy is investigated employing the polymer electrolyte poly(allylamine hydrochloride) (PAH) to regulate crystallization and passivate defect states in perovskite films on flexible substrates.

Association between adherence to behavioral intervention and capability well-being among parents of autistic children: a cross-sectional study from China.

Background: High adherence to behavioral interventions among parents of autistic children contribute to improvement in children's behaviors and parental outcomes. However, most of previous studies focused on the effects of intervention adherence on health-related well-being among parents, which is inadequate to capture the multi-dimensional parental burden of caring for autistic children. The aim of this study is to assess the association between parents' adherence to behavioral intervention and their capability well-being.

Comparing the protection of heterologous booster of inhaled Ad5-nCoV vaccine and hybrid immunity against Omicron BA.5 infection: a cohort study of hospital staff in China.

Background: After the exit "zero-COVID" strategy in mainland China by the end of 2022, a large-scale COVID-19 outbreak seeded by Omicron variants occurred. An inhaled adenovirus type-5 vector-based (i.e.

Spall: accurate and robust unveiling cellular landscapes from spatially resolved transcriptomics data using a decomposition network.

Recent developments in spatially resolved transcriptomics (SRT) enable the characterization of spatial structures for different tissues. Many decomposition methods have been proposed to depict the cellular distribution within tissues. However, existing computational methods struggle to balance spatial continuity in cell distribution with the preservation of cell-specific characteristics.

MiR-378 exaggerates angiogenesis and bone erosion in collagen-induced arthritis mice by regulating endoplasmic reticulum stress.

Rheumatoid arthritis (RA) is a chronic autoimmune disorder marked by pain, inflammation, and discomfort in the synovial joints. It is critical to understand the pathological mechanisms of RA progression. MicroRNA-378 (miR-378) is highly expressed in the synovium of RA patients and positively correlated with disease severity, but its function and underlying mechanisms remain poorly understood.

One Stone for Multiple Birds: Copolymer with Multifunctional Groups Boosts the Cycling Stability of Lithium Cobalt Oxide Cathodes at 4.5 V.

High-voltage LiCoO is a promising cathode material for ultrahigh-energy lithium-ion batteries, particularly in the commercialization of 5G technology. However, achieving long-term operational stability remains a significant challenge. Herein, a quaterpolymer additive with multiple functional groups is introduced to enhance the electrochemical performance of LiCoO cathode at 4.

Modeling the Global Impact of Chlorine Chemistry on Secondary Organic Aerosols.

Simulation of secondary organic aerosol (SOA) in models has been an uncertain component in determining the impacts of atmospheric aerosols on air quality and climate. Recent studies have shown that reactive chlorine can rapidly oxidize volatile organic compounds (VOCs), trigger SOA formation, and alter other oxidants, thus having a potentially significant effect on SOA, which has not been thoroughly investigated at the global scale. Here, we developed a chlorine-SOA simulation within a global chemical transport model along with updated anthropogenic continental chlorine emissions.