[Primary antibody deficiencies and respiratory manifestations in adults].

Primary antibody deficiencies (PAD) are a group of congenital disorders caused by genetic defects that affect the development and function of the body's immune defence mechanisms. Patients with PAD may present with recurrent infections, lymphoproliferation, autoimmune diseases, autoinflammation, or malignancies. Respiratory system manifestations may include bronchiectasis, bronchial asthma, and interstitial lung disease, among others.

[Hyper-IgE syndrome in adults characterized by disseminated mixed infection: a case report and literature review].

To improve the awareness of hyper-IgE syndrome (HIES) characterized by disseminated infection. We retrospectively analyzed a patient with HIES characterized by and mixed disseminated infection in Shenzhen People's Hospital. The clinical manifestations, results of laboratory tests/genetic examinations, therapeutic strategies and prognosis were summarized.

[Two families with Birt-Hogg-Dubé syndrome:case report and literature review].

To improve the awareness of Birt-Hogg-Dubé syndrome. We performed a retrospective analysis with two families of Birt-Hogg-Dubé syndrome (BHD syndrome) diagnosed in Department of Respiratory and Critical Care Medicine, Shenzhen People's Hospital from 2020 to 2021. Clinical manifestations, imaging features, diagnosis and gene detection results were summarized.