Two-point methods for evaluation of the minimum zone circle.

According to the cross-distribution of four control points of the minimum zone circle, the four-point conditions that two control points on the circumscribed circle and two control points on the inscribed circle meet are proposed. Based on these conditions, a two-point method is proposed, which is suitable not only for the determination of two control points on the circumscribed circle but also for the determination of two control points on the inscribed circle. In the iterative process, redundant data points can be simply determined by using dichotomy in order to improve computational efficiency.

MicroRNA-17/20a impedes migration and invasion via TGF-β/ITGB6 pathway in esophageal squamous cell carcinoma.

Patients with esophageal squamous cell carcinoma (ESCC) have an overall poor prognosis due to invasion and metastasis. Although it has been studied extensively, the metastatic mechanisms of ESCC remains largely unclear. Here, we evaluated microRNA expression in ESCC cell sublines with distinct motility and found that microRNA-17 and microRNA-20a (miR-17/20a) dramatically impeded cell migration and invasion of ESCC in vitro and decreased pulmonary arrest in vivo.