4 results match your criteria: "Shenzhen Baoan District Hospital of Traditional Chinese Medicine[Affiliation]"
Article Synopsis
- P2X7 receptor (P2X7R) is an ATP-gated ion channel linked to neuroinflammation and neurodegenerative diseases, making it a potential therapeutic target.
- The review details P2X7R's structure, role in microglial cell function, calcium signaling, and its involvement in diseases like Alzheimer's, Parkinson's, and multiple sclerosis.
- It also discusses the balance between neuroprotective and neurotoxic effects of P2X7R, the development of P2X7R antagonists in clinical trials, and highlights future research opportunities in this area.
Three-needle electroacupuncture ameliorates depressive-like behaviors in a mouse model of post-stroke depression by promoting excitatory synapse formation via the NGL-3/L1cam pathway.
Brain Res
October 2024
Shenzhen Baoan District Hospital of Traditional Chinese Medicine, Shenzhen, Guang Dong 518000, China. Electronic address:
Three-needle electroacupuncture (TNEA) has shown promise as a non-pharmacological treatment for post-stroke depression (PSD). However, the underlying mechanisms of its therapeutic effects remain unclear. In this study, we investigated the potential molecular and synaptic mechanisms by which TNEA ameliorates depressive-like behaviors in a mouse model of PSD.
View Article and Find Full Text PDFExploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer Integrating Network Pharmacology and Experimental Validation and .
Front Pharmacol
March 2022
Surgery of Traditional Chinese Medicine, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Drug resistance is the major cause of increasing mortality in prostate cancer (PCa). Therefore, it an urgent to develop more effective therapeutic agents for PCa treatment. Xihuang pills (XHP) have been recorded as the efficient anti-tumor formula in ancient Chinese medical literature, which has been utilized in several types of cancers nowadays.
View Article and Find Full Text PDFEffect of Electro-acupuncture on Vasomotor Symptoms in Rats with Acute Cerebral Infarction Based on Phosphatidylinositol System.
Chin J Integr Med
February 2022
Key Laboratory of Acupuncture of Tianjin, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, 300381, China.
Objective: To investigate the effect of electro-acupuncture (EA) on vasomotor symptoms in rats with acute cerebral infarction, by observing the changes in the expression of factors related to the phosphatidylinositol (PI) system.
Methods: Forty-two Wistar rats were randomly divided into 3 groups by a random number table: the control group (n=6), the model group (n=18) and the EA group (n=18). The EA group was given EA treatment at Shuigou (GV 26) instantly after modeling with middle cerebral artery occlusion (MCAO) method, while the model and control groups were not given any treatment.