[Expression of insulin receptor substrates in pancreas of rats with intrauterine growth retardation].

Objective: To study the expression of insulin receptor substrate-1(IRS-1) and insulin receptor substrate-2 (IRS-2) in pancreas of rats with intrauterine growth retardation (IUGR).

Methods: An IUGR rat model was prepared by protein malnutrition during pregnancy. The pancreas samples of the IUGR pups were obtained at birth, and 3 weeks and 8 weeks of age.

[Pathogens distribution and drug sensitivity of infantile dacryocystitis].

Objective: To investigate the pathogens and drug tolerance of infantile dacryocystitis in order to provide evidence for clinical drug use.

Methods: 230 cases of infant dacryocystitis (aged from 2 to 10 months, average 90 days) were analyzed for bacterial culture and drug sensitivity tests. These tests were performed following National Guide to Clinical Laboratory Procedures.

[Effect of glutamine on apoptosis of the small intestine in young rats with endotoxemia and its mechanism].

Objective: To study the effect of glutamine on intestinal epithelial apoptosis by examining changes regarding Bcl-2 and Bax mRNA expressions in the small intestine of young rats with endotoxemia and to explore the protective mechanism that glutamine may have.

Methods: A total of 120 18-day-old rats were randomly assigned into Endotoxemia, Glutamine-treated and Control groups (n = 40 each). The endotoxemia model was established by intraperitoneal injection of endotoxin (4 mg/kg of O55B5 Escherichia coli lipopolysaccharide).