5 results match your criteria: "Shaukat Khanum Memorial Cancer Hospital and Research Centre Lahore[Affiliation]"
Persistent Challenges: A Recurrent Adamantinoma - Case Report.
J Orthop Case Rep
July 2024
Department of Orthopedics, Shaukat Khanum Memorial Cancer Hospital and Research Centre Lahore, Pakistan.
Introduction: Adamantinoma is a rare, locally aggressive bone tumor that primarily affects the long bones, with a predilection for the tibia. Although considered a low-grade malignancy, adamantinoma is notorious for its high propensity for recurrence, which poses significant clinical challenges in the management of affected individuals. This case report aims to explore the intricacies of recurrent adamantinoma of the tibia, shedding light on its clinical presentation, diagnostic modalities, treatment strategies, and prognostic factors.
View Article and Find Full Text PDFComprehensive multi-level expression profiling of key biomarkers in breast cancer patients.
Am J Transl Res
October 2023
Department of Botany and Microbiology, College of Science, King Saud University P.O. Box 2455, Riyadh 11451, Saudi Arabia.
Article Synopsis
- The study aimed to identify and validate key biomarkers that can improve the diagnosis and prognosis of breast cancer (BC), along with exploring their potential as therapeutic targets.* -
- Researchers used a combination of literature reviews, bioinformatic analysis, and experimental validation, ultimately identifying four significant biomarkers: progesterone receptor (PGR), epidermal growth factor receptor (EGFR), estrogen receptor 1 (ESR1), and ERBB2.* -
- Results showed that PGR and EGFR were down-regulated, while ESR1 and ERBB2 were up-regulated in BC samples, indicating their importance in diagnosing and predicting patient outcomes, with implications for potential drug therapy.*
Human Papillomavirus Genotype Distribution in Invasive Cervical Cancer in Pakistan.
Cancers (Basel)
July 2016
Unit of Infections and Cancer (UNIC), Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO)-IDIBELL, L'Hospitalet de Llobregat, Gran Via de l'Hospitalet, 199-203, 08908 L'Hospitalet de Llobregat, Barcelona, Spain; CIBER Epidemiología y Salud Pública (CIBERESP). Madrid, Spain.
Few studies have assessed the burden of human papillomavirus (HPV) infection in Pakistan. We aim to provide specific information on HPV-type distribution in invasive cervical cancer (ICC) in the country. A total of 280 formalin-fixed paraffin-embedded tissue blocks were consecutively selected from Shaukat Khanum Memorial Cancer Hospital and Research Centre (Lahore, Pakistan).
View Article and Find Full Text PDFDiffusion Lung Capacity Changes In Hodgkin Lymphoma Patients Before And After Abvd Chemotherapy.
J Ayub Med Coll Abbottabad
December 2017
Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre Lahore, Pakistan.
Background: Chemotherapy consisting of Adriamycin, Bleomycin, Vinblastine, and Doxorubicin (ABVD), which is the mainstay of treatment in Hodgkin's Lymphoma (HL), is associated with both acute and long-term pulmonary toxicity primarily due to Bleomycin. Bleomycin induced pulmonary toxicity (BPT) is clinically detected using diffusing lung capacity for carbon monoxide (DLCO). The objective of this study was to evaluate changes in DLCO in HL patients before and after ABVD chemotherapy.
View Article and Find Full Text PDFOnsite cytopathology evaluation and ancillary studies beneficial in EUS-FNA of pancreatic, mediastinal, intra-abdominal, and submucosal lesions.
Diagn Cytopathol
April 2015
Department of Internal Medicine, Shaukat Khanum Memorial Cancer Hospital and Research Centre Lahore, Pakistan.
Introduction: Endoscopic ultrasound-guided fine needle aspiration cytology (EUS-FNA) is considered to be a minimally invasive and safe technique, with low complication rates, for obtaining tissue samples from pancreatic lesions, and mediastinal and intra-abdominal nodes. We retrospectively reviewed the diagnostic accuracy of this method at a tertiary care hospital in Pakistan.
Methods: The medical records of 393 consecutive patients referred to the gastroenterology service from August 2008 to September 2013 were reviewed in this retrospective study.