4 results match your criteria: "Shaoxing People's Hospital and Shaoxing Hospital of Zhejiang University[Affiliation]"
Anti-CD24 neutralizing antibody exacerbates Concanavalin A-induced acute liver injury in mice via liver M1 macrophages.
Immunol Lett
January 2017
Department of Immunology, School of Basic Medical Sciences, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Educational Ministry of China, Tianjin Medical University, Tianjin 300070, China. Electronic address:
Liver largely relies on its innate immunity to initiate quick and effective defense against potentially toxic agents, and innate immune cells are major players in this process. However, excessive inflammation due to out-of-control immune response may eventually cause liver injury. Thus, it is important to fully understand the regulatory mechanisms associated with liver inflammation.
View Article and Find Full Text PDFEnhanced NLRP3, caspase-1, and IL- 1β levels in degenerate human intervertebral disc and their association with the grades of disc degeneration.
Anat Rec (Hoboken)
April 2015
Department of Anesthesiology, Shaoxing People's Hospital and Shaoxing Hospital of Zhejiang University, Shaoxing, People's Republic of China.
The NACHT, LRR, and PYD domains-containing protein 3 (NLRP3) inflammasome plays an important role in a variety of diseases. However, the role of NLRP3 in the human intervertebral disc (IVD) degeneration remains unknown. In the present study, we assessed the expression levels of the NLRP3 inflammasome and its downstream targets caspase-1 and IL-1β in 45 degenerate and seven nondegenerate IVD samples.
View Article and Find Full Text PDFSensitive HPV genotyping based on the flow-through hybridization and gene chip.
J Biomed Biotechnol
April 2013
Department of Gynecology, Shaoxing People's Hospital and Shaoxing Hospital of Zhejiang University, Shaoxing 312000, China.
Persistent infection of high-risk human papillomavirus (HPV) has been recognized as the direct cause of cervical carcinoma. Therefore, detection and genotyping of HPV are important to cervical-cancer screening. In this study, we have evaluated the efficacy of flow-through hybridization and gene chip (HybriMax) on HPV genotyping through comparison of the results with Hybrid Capture II (HC-II) and in situ hybridization (ISH).
View Article and Find Full Text PDFOverexpression of tyrosine kinase receptor B promotes metastasis of ovarian serous adenocarcinoma by lymphangiogenesis.
Tumori
April 2012
Department of Gynecology, Shaoxing People’s Hospital and Shaoxing Hospital of Zhejiang University, No. 568 Zhongxing Road, Shaoxing, China.
Aims And Background: The aim of this study was to detect the expression features of tyrosine kinase receptor B (TrkB) and analyze the possible correlation between TrkB expression and lymph vessel density (LVD) in metastasis of ovarian serous adenocarcinoma.
Methods: An immunohistochemical method was used to evaluate TrkB expression in 139 ovarian tumor sections (103 primary ovarian serous adenocarcinomas and 36 serous adenomas) and investigate the correlation between TrkB expression and LVD, which was estimated by means of VEGFR-3 assessment.
Results: TrkB was significantly upregulated in serous adenocarcinomas and absent in serous adenomas.