Factor structure and longitudinal invariance for the Chinese Mainland version of the Edinburgh postnatal depression scale during pregnancy.

Background: There are inconsistent results on the Edinburgh Postnatal Depression Scale's (EPDS) factor structure and longitudinal invariance among different cultures. Furthermore, limited relevant studies in Chinese pregnant women exist.

Purpose: To test the factor structure of the Chinese Mainland EPDS during pregnancy and conduct longitudinal invariance analyses.

Prevalence and Trends of Birth Defects - Five Counties, Shanxi Province, China, 2003-2022.

What Is Already Known About This Topic?: The Shanxi Province, located in northern China, holds the highest prevalence of birth defects (BDs) across the country. Following the implementation of a nationwide folic acid supplementation program in 2009, a significant reduction of 53.89% in the prevalence of neural tube defects (NTDs) was observed in Shanxi from 2012 to 2017.

Mutations in CFTR genes are associated with oligoasthenospermia in infertile men undergoing IVF.

Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation has been clearly defined in congenital absence of the vas deferens (CAVD), which is an important cause of obstructive azoospermia. However, the association between oligoasthenospermia and CFTR gene mutation remains controversial. To confirm this issue, 151 infertile Chinese men were screened for CFTR mutation by NGS approach, including 18 CAVD patients, 72 patients with severe oligoasthenospermia and 61 controls with normal sperm parameters.

The WNT/β-catenin signaling pathway may be involved in granulosa cell apoptosis from patients with PCOS in North China.

Introduction: Investigate the expressions of WNTs in granulosa cells of PCOS in North China, and explore the possible mechanism.

Material And Methods: Patients with PCOS (n=40) and controls without PCOS (n=20) were enrolled into the study. The levels of serum sex hormone were detected by chemiluminescent enzyme immunoassay.

Mutational screening of the INSL3 gene in azoospermic males with a history of cryptorchidism.

The insulin-like factor 3 (INSL3 ) gene encodes 131 amino acids, consisting of two exons. In human beings, mutations of this gene may lead to bilateral cryptorchidism and infertility. However, the role of INSL3 in male spermatogenesis still remains controversial.

Association between FSHR polymorphisms and polycystic ovary syndrome among Chinese women in north China.

Purpose: Polycystic ovary syndrome (PCOS) is a common endocrine disorder disease among women in reproductive-age. Since follicle stimulating hormone (FSH) exerts important biological functions, the association between PCOS and FSH receptor (FSHR) polymorphisms attracts wide attention. The aim of this study was to evaluate whether polymorphisms of FSHR at 307 and 680 codons are associated with PCOS patients in China.