6 results match your criteria: "Shanghai YangPu District KongJiang Hospital[Affiliation]"
Correlations between SHBG, Sex Hormones, Inflammation, and Neurocognitive Decline in Alzheimer's Disease: A Retrospective Study.
Curr Alzheimer Res
January 2025
Department of Neurology, Shanghai Yangpu District Kongjiang Hospital, Shanghai, China.
Background: Alzheimer's Disease (AD) is characterized by a progressive neurodegenerative process leading to cognitive decline and functional impairment. Endocrine factors, particularly sex hormones and their binding proteins, play a critical role in AD pathophysiology. Understanding the relationship between these factors and AD is essential for developing targeted interventions.
View Article and Find Full Text PDFCorrigendum: Establishment of noncycloplegic methods for screening myopia and pre-myopia in preschool children.
Front Med (Lausanne)
April 2024
Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.
[This corrects the article DOI: 10.3389/fmed.2023.
View Article and Find Full Text PDFMelittin induces autophagy to alleviate chronic renal failure in 5/6-nephrectomized rats and angiotensin II-induced damage in podocytes.
Nutr Res Pract
April 2024
Geriatric Department, Shanghai Yangpu District Kongjiang Hospital, Shanghai 200093, China.
Background/objectives: Chronic renal failure (CRF) is a complex pathological condition that lacks a cure. Certain Chinese medicines, such as melittin, a major component in bee venom, have shown efficacy in treating CRF patients. On the other hand, the mechanisms underlying the therapeutic effects of melittin are unclear.
View Article and Find Full Text PDFEstablishment of noncycloplegic methods for screening myopia and pre-myopia in preschool children.
Front Med (Lausanne)
December 2023
Shanghai Eye Disease Prevention and Treatment Center, Shanghai Eye Hospital, Shanghai, China.
Article Synopsis
- The study highlights that pre-myopia is a significant concern for preventing myopia in young children, particularly those under 3 years old, as it increases their risk of developing myopia.
- Conducted in 16 kindergartens in Shanghai, the research evaluated noncycloplegic screening methods, analyzing visual acuity and refractive measurements from 1,308 preschoolers to find the prevalence of myopia and pre-myopia.
- Results indicated that while using uncorrected distance visual acuity alone was not effective, combining axial length and the corneal curvature ratio with spherical equivalent measurements offered better accuracy in screening both pre-myopia and myopia in young children.
Advanced glycation end products promote the progression of chronic kidney diseases by targeting calpain 6.
Amino Acids
July 2023
Geriatric Department, Shanghai YangPu District KongJiang Hospital, ShuangYang Rd No. 480, YangPu District, Shanghai, 200093, China.
Advanced glycation end products (AGEs) are produced by glycosylation or oxidation of proteins and lipids and are tightly involved in the chronic kidney disease (CKD) process. Calpain 6 (CAPN6) is a non-classical calpain that has been reported to be overexpressed in CKD. This study aimed to explore the effects of AGEs in CKD progress and their correlation with CAPN6.
View Article and Find Full Text PDFLong non-coding RNA HOTTIP induces inflammation in asthma by promoting EFNA3 transcription by CCCTC-binding factor.
Am J Transl Res
December 2022
Department of Respiratory, Shanghai Yangpu District Kongjiang Hospital Shanghai, China.
Objective: Long non-coding RNAs (lncRNAs) function as vital regulators in biologic processes and are dysregulated in various tumors; however, little is known about their role in the inflammatory response in asthma. Therefore, this study aimed to investigate the function of antisense HOXA terminal transcriptional RNA (HOTTIP) and its possible mechanism in the ovalbumin (OVA)-induced inflammatory response in asthmatic mice.
Methods: Asthma-related data resources from the Gene Expression Omnibus (GEO) database were extracted to explore the relationships between lncRNAs and asthma, and the lncRNA HOTTIP was identified.