7 results match your criteria: "Shanghai Tenth People's Hospital of Tongji University Shanghai 200072[Affiliation]"
Scaffold-free cartilage cell sheet combined with bone-phase BMSCs-scaffold regenerate osteochondral construct in mini-pig model.
Am J Transl Res
October 2018
Department of Oral and Maxillofacial Surgery, University of Texas Health Science Center at San Antonio TX, USA.
Article Synopsis
- Tissue-engineered condyles hold promise for treating advanced osteoarthritis in the temporomandibular joint, but current methods face challenges in large animal models.
- A study compared two approaches: a cell sheet group using cartilage cells and BMSC-PCL/HA scaffolds, and a biphase scaffold group using chondrocytes on a PGA/PLA scaffold.
- Results showed that the cell sheet group successfully regenerated healthy osteochondral structures, while the biphase scaffold group failed, emphasizing the effectiveness of cartilage cell sheets in tissue regeneration.
Molecular mechanisms underlying application of serum procalcitonin and stool miR-637 in prognosis of acute ischemic stroke.
Am J Transl Res
October 2016
Department of Neurology, Shanghai Tenth People's Hospital of Tongji University Shanghai 200072, China.
Article Synopsis
- Researchers found that serum procalcitonin (PCT) levels can predict long-term mortality in Chinese patients following acute ischemic stroke (AIS).
- The study also linked lower levels of stool microRNA-637 (miR-637) with higher long-term mortality rates after AIS, suggesting an inverse relationship between miR-637 and PCT.
- Further analysis showed that miR-637 inhibits the production of PCT in intestinal neuroendocrine cells, indicating that reduced miR-637 during AIS allows for increased PCT release into the bloodstream.
Prognostic value of melanoma cell adhesion molecule expression in cancers: a meta-analysis.
Int J Clin Exp Med
November 2015
Department of Clinical Laboratory Medicine, Shanghai Tenth People's Hospital of Tongji University Shanghai 200072, China.
Melanoma cell adhesion molecule (MACM) has been reported in many studies as a novel bio-marker for its prognosis value in cancers. But the prognosis significance of MACM expression in cancer remains inconclusive. Therefore, we conducted a system review and meta-analysis to assess its prognosis value in cancers.
View Article and Find Full Text PDFAstragalus polysaccharide suppresses palmitate-induced apoptosis in human cardiac myocytes: the role of Nrf1 and antioxidant response.
Int J Clin Exp Pathol
March 2016
Department of Cardiology, Tongji Hospital of Tongji University Shanghai 200072, China.
Objective: Previous studies have shown that Astragalus polysaccharides (APS) can be used to ameliorate cardiotoxicity due to chemotherapy and improve the cardiac function. However, the mechanism by which APS mediate this effect is unclear. In the present study, the effects of APS, which suppressed ROS-mediated apoptosis through Nrf1 accumulation in human cardiac myocytes (HCMs), was investigated.
View Article and Find Full Text PDFAssociation of three common BARD1 variants with cancer susceptibility: a system review and meta-analysis.
Int J Clin Exp Med
March 2015
Department of Oncology, Tongren Hospital, Shanghai Jiaotong University School of Medicine Shanghai 200336, China.
BARD1 has been shown to play tumor suppressive roles in human cancer. We performed this meta-analysis and firstly evaluated the association between three common BARD1 polymorphisms (Arg378Ser, Val507Met and Pro24Ser) and cancer susceptibility. We performed this meta-analysis following PRISMA guidelines.
View Article and Find Full Text PDFPrognostic significance of interleukin 17 in cancer: a meta-analysis.
Int J Clin Exp Med
November 2014
Department of Clinical Laboratory Medicine, Shanghai Tenth People's Hospital of Tongji University Shanghai 200072, China.
The prognostic value of Interleukin 17 (IL-17) in cancer patients is currently under debate and remains inconclusive. We performed a systematic review and meta-analysis to evaluate the role of IL-17 as a prognostic marker in cancer. Hazard ratios (HRs) and corresponding 95% confidence intervals (CIs) were combined to measure the effective value of IL-17 expression on prognosis.
View Article and Find Full Text PDFCBX8, a novel DNA repair protein, promotes tumorigenesis in human esophageal carcinoma.
Int J Clin Exp Pathol
June 2015
Department of Gynaecology and Obstetrics, Shanghai Tenth People's Hospital of Tongji University Shanghai 200072, China.
DNA damage response and repair are carried out by certain proteins following damage by environmental clastogens, such as ionizing radiation and reactive oxygen species. It has been reported that many carcinomas that are characterized by resistance to chemotherapy and poor outcomes show dysfunction of these proteins. Chromobox homologue 8 (CBX8), a member of the polycomb group of proteins, has been identified as a factor that protects tumor cells from the detrimental effects of ionizing radiation (IR) or hydrogen peroxide (H2O2).
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