1 results match your criteria: "Shanghai Stomatological Disease Hospital. Shanghai 200001[Affiliation]"
[Effects of lyophilized on the biological activities of lentiviral vector of bone morphogenetic protein 2].
Shanghai Kou Qiang Yi Xue
October 2016
Shanghai Stomatological Disease Center, Shanghai Stomatological Disease Hospital. Shanghai 200001, China.
Article Synopsis
- The study aimed to explore how lyophilization (a freeze-drying process) affects the biological activity of recombinant lentiviral vectors carrying bone morphogenetic protein 2 (BMP-2).
- Prior to and after lyophilization, tests showed no significant change in how the lyophilized lenti-BMP-2 affected the proliferation of rat bone marrow stromal cells (BMSCs) or the expression of key proteins like BMP-2.
- The results indicate that using trehalose in the lyophilization process effectively preserves the activity of lenti-BMP-2, making it a reliable method for long-term storage.