4 results match your criteria: "Shanghai Pudong New Area Peoples' Hospital[Affiliation]"

Derivation of induced pluripotent stem cell SHEHDNi002-A from a 68-year-old Chinese Han Parkinson's disease patient carrying LRRK2 and DNAJC6 mutations.

Stem Cell Res

March 2024

Department of Neurology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai 200092, China. Electronic address:

Parkinson's disease (PD) is a common movement disorder. In this study, we generated an induced pluripotent stem cell (iPSC) line from the dermal fibroblasts of a 68-year-old female patient, carrying LRRK2 and DNAJC6 mutations. This iPSC line will be a useful tool for investigating the pathogenesis and for developing treatment for PD.

View Article and Find Full Text PDF

Modified Ni-Nail and C-Nail systems for intra-articular fractures of the calcaneus: A biomechancial study.

Injury

December 2022

Department of Orthopaedics, Shanghai Pudong New Area Peoples' Hospital, Shanghai 201299, China; Department of Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China. Electronic address:

Objectives: We have proposed a novel intramedullary nail (Ni-Nail) by incorporating a sustentaculum tali screw to improve the fixation stability of minimally invasive treatment for calcaneal fractures. This study aimed to evaluate the biomechanical characters of the Ni-Nail system and compare it with traditional C-Nail system.

Methods: A finite element model of a Sanders type-IIIAB calcaneal fracture was reconstructed and fixed using two intramedullary nail systems, which was validated by a cadaver study.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates the biomechanical stability of the Magic screw for treating acetabular posterior column fractures using finite element analysis.
  • It generates a three-dimensional model from CT and MRI data, simulates forces similar to human gravity, and compares four fixation methods' effectiveness.
  • Results show that the Magic screw exhibits lower stress levels and more uniform stress distribution than traditional methods, suggesting it should be recommended for better stability in fracture treatment.
View Article and Find Full Text PDF

Objective: Long-term acupoint stimulation (LAS), also called embedding acupuncture, is a modified acupuncture technique. The preliminary results have demonstrated its efficacy in body-weight control. However, the low quality of available trials limited its application.

View Article and Find Full Text PDF