24 results match your criteria: "Shanghai Oriental Hospital[Affiliation]"

Objective: To investigate the prognostic value of albumin (ALB), aspartate aminotransferase/alanine aminotransferase ratio (AST/ALT) in patients with acute liver failure (ALF) in hyperacute phase of sepsis which provided the basis for clinical evaluation and prognostic judgment and corresponding treatment options.

Methods: A multicenter retrospective cohort study was conducted. Patients with ALF in hyperacute phase of sepsis admitted to Zhoupu Hospital Affiliated to Shanghai Health College, Shanghai Pudong New Area People's Hospital, and Shanghai Oriental Hospital from January 2019 to February 2024 were enrolled.

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  • The study aimed to evaluate the safety and effectiveness of a varicose vein sealant kit for treating dysfunction in the great saphenous vein through a randomized controlled trial involving 180 patients across 9 hospitals.
  • Participants were divided into an experimental group, which used the sealant kit, and a control group, which received radiofrequency ablation, with their outcomes compared after surgery.
  • The main focus was on the complete closure rate of the great saphenous vein at 3 months post-surgery, along with other secondary measures, including pain levels and overall complication rates, to determine if the sealant kit was as effective as traditional methods.
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A bibliometric analysis and evaluation of research on non- species (NHPHs) is essential to determining future research directions. A comprehensive search was carried out using predetermined search terms within the Web of Science Core Collection (WoSCC) to gather publications spanning from 1993 to 2023. VOSviewer and Citespace were employed for data analysis and visualization.

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Background: Chloasma is a common skin hyperpigmentation condition, with treatment options ranging from topical agents to advanced interventions such as chemical peels and laser therapy. Salicylic acid, including its supramolecular form (SSA), has shown promise in managing chloasma. However, to date, no multicentre randomized controlled trial of SSA for chloasma is available.

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  • The text discusses software designed to predict the effects of aging on physical appearance, emphasizing the need for a deeper understanding of skin aging factors.
  • It outlines the creation of Causal Bayesian Belief Networks (CBBNs) built with input from experienced dermatologists to forecast skin aging over a 15-year period, focusing on various skin types.
  • The results suggest the model can effectively predict the progression of clinical signs of aging, particularly for African skin, and is intended to serve as a preventive tool that could integrate with AI for visualizing aging and skin conditions.
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  • The study looked at patients with severe strokes who were treated successfully but still had bad outcomes or deaths in the following 90 days.
  • It involved 207 people from a trial in China and found that 38% had poor results, while 12.6% died after treatment.
  • Key risk factors for dying or having bad outcomes included being older than 67, having specific types of artery blockage, and having a high initial stroke severity score.
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Background: In a previous study, autologous bone marrow infusion (ABMI) was performed in patients with decompensated liver cirrhosis (DLC) and acquired immunodeficiency syndrome and achieved good results, but whether splenectomy affected outcome was unclear.

Aim: To investigate the efficacy of ABMI combined with splenectomy for treatment of DLC.

Methods: Eighty-three patients with DLC were divided into an intervention group (43 cases) and control group (40 cases) according to whether splenectomy was performed.

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  • The study aimed to compare the safety and efficacy of the Neurohawk retriever and the Solitaire FR for treating acute ischemic stroke caused by large vessel occlusion, using a randomized controlled trial with a focus on non-inferiority.
  • A total of 232 patients participated, showing a successful reperfusion rate of 88.70% for Neurohawk and 90.60% for Solitaire, with no significant differences in safety outcomes or overall effectiveness between the two devices.
  • Subgroup analyses indicated that both devices performed similarly in terms of outcomes, regardless of whether the strokes were caused by intracranial atherosclerotic disease or other factors, with comparable rates of all-cause mortality within 90 days.
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Objective: The objective of this study was to assess the comparative efficacy in third-line setting for metastatic CRC (mCRC) patients using matched population of FRESCO trial with fruquintinib and real-world data with other TKIs.

Materials And Methods: The arm of fruquintinib from the FRESCO phase III trial (NCT02314819) included the data of patients with metastatic CRC that progressed after at least two lines of chemotherapy and received fruquintinib treatment. An external control arm was constructed using real-world data (RWD) of patients who received other TKIs based on key eligibility criteria of FRESCO.

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Acute and chronic maternal exposure to fine particulate matter and prelabor rupture of the fetal membranes: A nation-wide survey in China.

Environ Int

December 2022

Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:

Background: Prelabor rupture of the fetal membranes (PROM) is a major contributor to adverse perinatal outcomes. Some epidemiologic studies explored the association between maternal PM exposure and PROM but failed to treat the labor induction and prelabor cesarean section as censored observations.

Objective: We aimed to evaluated whether acute and chronic maternal ambient PM exposure may increase the risk of PROM in China.

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Background: A dental Implant is a prosthetic device made of alloplastic materials implanted into the bone to provide retention and support for a dental prosthesis. Sirtuin1 (SIRT1) molecule, a nicotinamide adenine dinucleotide (NAD)-dependent histone deacetylase, regulates a variety of physiological and pathological processes, including oxidative stress, metabolism, cell proliferation, cell differentiation, inflammatory, and apoptosis. We explored whether the expression of SIRT1 correlates in patients receiving implants with peri-implant mucositis (PIM) and peri-implantitis (PI) in comparison to patients with healthy peri-implant area (PIH).

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[Clinical analysis of pulmonary nocardiosis associated with bronchiectasis].

Zhonghua Jie He He Hu Xi Za Zhi

March 2022

Department of Respiratory and Critical Care Medicine, Peking Union Medical College Hospital, Beijing 100005,China.

To better understand the clinical characteristics of pulmonary nocardiosis associated with bronchiectasis. Patients diagnosed as bronchiectasis complicated with pulmonary nocardiosis in 9 tertiary general hospitals in China were enrolled from March 2016 to March 2020, with the record of general data, imaging performance and pathogen. The literature was reviewed.

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Purpose: The three-dimensional (3D) sequence of magnetic resonance imaging (MRI) plays a critical role in the imaging of musculoskeletal joints; however, its long acquisition time limits its clinical application. In such conditions, compressed sensing (CS) is introduced to accelerate MRI in clinical practice. We aimed to investigate the feasibility of an isotropic 3D variable-flip-angle fast spin echo (FSE) sequence with CS technique (CS-MATRIX) compared to conventional 2D sequences in knee imaging.

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The Chinese consensus for surgical treatment of traumatic rib fractures 2021 (C-STTRF 2021).

Chin J Traumatol

November 2021

Department of Cardiothoracic Surgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, 400014, China; Department of Trauma Surgery, Chongqing Emergency Medical Center, Chongqing University Central Hospital, Chongqing, 400014, China. Electronic address:

Rib fracture is the most common injury in chest trauma. Most of patients with rib fractures were treated conservatively, but up to 50% of patients, especially those with combined injury such as flail chest, presented chronic pain or chest wall deformities, and more than 30% had long-term disabilities, unable to retain a full-time job. In the past two decades, surgery for rib fractures has achieving good outcomes.

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Background: This study was aimed to compare the sensitivity of transrectal ultrasound (TRUS) guided systematic biopsy (TRUS-SB), superb microvascular imaging guided targeted biopsy (SMI-TB), and elastography ultrasound guided targeted biopsy (EU-TB) in detecting prostate cancer (PCa).

Methods: One hundred and eighty-four patients with suspicious PCa were randomly divided into two groups, SMI-TB group (n=92) and EU-TB group (n=92). All the patients received a 2-core SMI-TB or a 2-core EU-TB before receiving a 12-core TRU-SB depending on the group.

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Objective: To explore the effect of percutaneous kyphoplasty (PKP) on lumbar-pelvic correlation in osteoporotic vertebral compressive fracture (OVCF).

Methods: According to the inclusion criteria, 63 patients with primary osteoporosis between January 2012 and June 2017 were selected as the control group and 67 patients with single-segment lumbar OVCF receiving PKP and complete clinical data were included as the observation group. There was no significant difference in gender, age, and lumbar spine bone density between the two groups ( >0.

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The occurrence of cerebral infarction commonly takes atherosclerosis as the pathophysiological basis, accompanied by chronic inflammation. Hypersensitive C-reactive protein (hs-CRP) is an important inflammatory factor involved in the formation of atherosclerosis. This study aims to investigate the regulation of hs-CRP expression by long-chain non-coding RNA (LncRNA) MALAT1 in acute cerebral infarction patients.

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Objective: To explore the effect on sagittal spine-pelvis balance of different fusion segments in anterior cervical discectomy and fusion (ACDF).

Methods: The clinical data of 326 patients with cervical spondylotic myelopathy, treated by ACDF between January 2010 and December 2016, was retrospectively analysed. There were 175 males and 151 females with an average age of 56 years (range, 34-81 years).

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[Effects of histone methyltransferase inhibitor on the polarization of peritoneal macrophages in septic mice].

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue

February 2019

Department of Emergency Medicine and Critical Care, East Hospital, Tongji University, Shanghai 200120, China.

Objective: To investigate the effect of histone methyltransferase (EZH2) inhibitor on the polarization of peritoneal macrophages in septic mice.

Methods: Thirty-six healthy male C57BL/6J mice were divided into three groups by random number table method (n = 12): sham operated group (Sham group), sepsis model group (CLP group) and EZH2 inhibitor treatment group (CLP+3-DZNeP group). Sepsis animal model was established by cecum ligation and puncture (CLP); Sham group was challenged only by cecum traction without ligation.

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Background: Primary pulmonary lymphoma (PPL) mainly comprises mucosa-associated lymphoid tissue (MALT) lymphoma as well as other subtypes of lymphoma. Different phenotypes of PPL demonstrate various high-resolution computed tomography (HRCT) features. We aimed to evaluate the value of HRCT in the diagnosis and differential diagnosis of PPL, especially between MALT lymphoma and non-MALT lymphoma and the correlation between CT and pathological features.

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Benign metastasizing leiomyoma (BML) in the lung is a very rare metastatic disease. BML accompanied with primary lung cancer is even more uncommon. In our report, a 38-year-old female who undertook routine computed tomography (CT) scan revealed the pulmonary abnormality.

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Purpose: To assess the stemness and regenerative potential of cryopreserved corneal stromal stem cells (cryo-CSSCs) after long-term storage. We also used the secretome from these cells to observe the effect on wound-healing capacity of corneal fibroblasts and on the expression of fibrotic markers during wound healing.

Methods: CSSCs were obtained from three donors and stored in liquid nitrogen for approximately 10 years.

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The invasion and metastasis of malignant tumor cells lead to normal tissue destruction and are major prognostic factors for many malignant cancers. Long non-coding RNA (LncRNA) is associated with occurrence, development and prognoses of non-small cell lung cancer (NSCLC), but its mechanisms of action involved in tumor invasion and metastasis are not clear. In this study, we screened and detected the expression of LncRNA in two NSCLC lines 95D and 95C by using high throughput LncRNA chip.

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Objective: To summarize the experiences in the treatment of distal radius fracture by locking pi-shaped plate internal fixation.

Methods: All the 32 cases (left 11, right 21) of unstable fractures of distal radius treated by locking pi plate fixation. Among them, 11 were male and 21 female with an average age of 36 years (range, from 23 to 67 years).

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