15 results match your criteria: "Shanghai No.8 People's Hospital[Affiliation]"
Mol Med Rep
November 2023
Department of Clinical Laboratory, Shanghai No. 8 People's Hospital, Shanghai 200235, P.R. China.
Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the GAPDH control western blotting data shown in Fig. 2B were strikingly similar to data appearing in different form in Fig. 1E in another article written by different authors at different research institutes [Liang T, Ye X, Liu Y, Qiu X, Li Z, Tian B and Yan D: FAM46B inhibits cell proliferation and cell cycle progression in prostate cancer through ubiquitination of β‑catenin.
View Article and Find Full Text PDFMol Med Rep
December 2020
Department of Clinical Laboratory, Shanghai No. 8 People's Hospital, Shanghai 200235, P.R. China.
Tripartite motif‑containing (TRIM) 14 is a protein of the TRIM family. Studies have indicated that TRIM14 may be used as an oncogene in tumor cells, such as osteosarcoma, non‑small cell lung cancer and breast cancer through different pathways. However, the functions of TRIM14 in cervical cancer cells remain unclear.
View Article and Find Full Text PDFOnco Targets Ther
June 2020
Department of General Surgery, Shanghai No.8 People's Hospital, Shanghai, People's Republic of China.
Background: Circular RNAs (circRNAs) have been documented as key regulators during progression of malignant human cancer, including colorectal cancer (CRC). However, the underlying molecular mechanisms of circNOL10 in CRC remain unclear.
Methods: The real-time quantitative polymerase chain reaction was used to quantify the expression of circNOL10, miR-135a-5p, miR-135b-5p, and Krüppel-like factor 9 (KLF9).
Exp Mol Pathol
April 2020
Department of Respiratory and Critical Care Medicine, Shanghai General Hospital, Shanghai JiaoTong University School of Medicine, Shanghai 200080, PR China. Electronic address:
This study aimed to investigate the protective effect of angiotensin converting enzyme 2 (ACE2) on lipopolysaccharide (LPS)-induced acute lung injury (ALI). After generating ALI mouse models by injecting LPS, the levels of ACE2, inflammatory factors, and downstream proteins of the LPS-TLR4 pathway were analyzed. LPS-challenged BEAS-2B cells were established in vitro.
View Article and Find Full Text PDFCancer Manag Res
October 2019
Department of Clinical Laboratory, Shanghai No. 8 People's Hospital, Shanghai, China.
Objective: : Chemotherapy failure derived from drug resistance is the most important reason causing the recurrence in colorectal cancer patients. Therefore, it is necessary to shed light on the mechanism of chemotherapy resistance in colorectal cancer patients.
Methods: : We looked into the contribution of and ANO1 to chemoresistance in the human colorectal carcinoma cell lines.
Neural Regen Res
August 2019
Department of Neurology, Shanghai No. 8 People's Hospital, Shanghai, China.
Rehabilitation training is believed to be beneficial to patients with stroke, but its molecular mechanism is still unclear. Rat models of cerebral ischemic stroke were established by middle cerebral artery occlusion/reperfusion, and then received treadmill training of different intensities, twice a day for 30 minutes for 1 week. Low-intensity training was conducted at 5 m/min, with a 10-minute running, 10-minute rest, and 10-minute running cycle.
View Article and Find Full Text PDFShanghai Kou Qiang Yi Xue
December 2018
Department of Stomatology, Shanghai No.8 People's Hospital. Shanghai 200235, China.
Purposes: To analyze the effect of low level laser treatment combined with basic therapy periodontal on cytokines and lipopolysaccharide, leptin in gingival sulcus of patients with diabetes mellitus complicated with chronic periodontitis (DMCP).
Methods: From January 2016 to January 2017, 80 patients with DMCP were randomly divided into experimental group and control group. Patients in the control group received basic periodontal therapy, while patients in the experimental group received low dose laser combined with basic periodontal treatment.
Shanghai Kou Qiang Yi Xue
February 2018
Department of Stomatology, Shanghai No.8 People's Hospital. Shanghai 201500, China.
Purpose: To observe the effect of overdose fluoride on the expression of TGF-β3 in rat incisor and to explore the possible mechanism of dental fluorosis. METHODS: Twenty Wistar rats were randomly divided into 2 groups. The animals were maintained in standard environmental conditions with free access to food and water (control group) or water added with 100mg/L F (experimental group). The rats were killed at the end of 8th week.
View Article and Find Full Text PDFOncol Lett
May 2018
Department of General Surgery, The Affiliated Shanghai No. 10 People's Hospital, Nanjing Medical University, Shanghai 200072, P.R. China.
The aim of the present study was to investigate the function of microRNA (miR)-486-5p in colorectal cancer (CRC). Tumor and adjacent normal mucosal tissue samples were collected from patients with CRC. Differences in the expression levels of miR-486-5p between tumor tissues and adjacent normal mucosal tissues were examined using reverse transcription-quantitative polymerase chain reaction.
View Article and Find Full Text PDFZhonghua Yi Xue Za Zhi
July 2012
Department of Orthopedics, Shanghai No. 8 People's Hospital, Shanghai 200235, China.
Objective: To explore the improvement of surgical procedure in recurrent onychocryptosis and evaluate its efficacy.
Methods: The meliorated procedure was designed based on the Winograd surgical protocol. A total of 145 cases of recurrent onychocryptosis were recruited into this retrospective study.
J Int Med Res
March 2010
Research Unit of Liver Disease, Shanghai No. 8 People's Hospital, Jiangsu University, Shanghai, China.
This study aimed to identify acute self-limited hepatitis B (ASL-HB) among patients presenting with hepatitis B virus (HBV)-related acute hepatitis. Data were available for 220 patients diagnosed with HBV-related acute hepatitis, of whom 164 had acute hepatitis B (AHB). Of these, 160 were confirmed as ASL-HB: three (1.
View Article and Find Full Text PDFZhonghua Wai Ke Za Zhi
November 2009
Department of Colorectal Surgery, Shanghai No.8 People's Hospital, Shanghai 200233, China.
Objective: To investigate the effect of the neoadjuvant chemoradiotherapy (NCR) on the healing of anastomosis following low anterior resection in patients with locally advanced rectal cancer.
Methods: Between May 2001 and August 2007, 192 patients with T3 and T4 low rectal cancer (distance from the tumor to anal verge = 6 cm) enrolled in the study. All patients were subjected to preoperative radiotherapy to pelvis, with a total dose of 40 - 46 Gy in 20 days fractions of 2 Gy each in 4 weeks and simultaneously combined with oral capecitabine (CAP) of 1250 mg/m(2) bid continuously for 10 weeks up to surgery.
Zhonghua Wai Ke Za Zhi
October 2009
Department of Colorectal Surgery, Shanghai No. 8 People's Hospital, Shanghai 200233, China.
Objective: To explore the possibility of further improvement of the efficacy of neoadjuvant chemoradiotherapy in locally advanced lower rectal cancer and the management of patients with clinical complete regression.
Methods: From May 2001 to August 2007, 192 cases with locally advanced lower rectal cancer (T3/T4 or N(+)) received preoperative radiotherapy 40 - 46 Gy/20 - 23 fractions and concomitant oral capecitabine 625 mg/m(2) bid for 10 weeks prior to surgery. Curative resection with total mesorectal excision (TME) was carried out 6 weeks after the end of radiation.
J Gastroenterol Hepatol
November 2008
Research Unit of Liver Disease, Shanghai No. 8 People's Hospital, Shanghai, China.
Background And Aim: In areas with high or intermediate endemicity for chronic hepatitis B virus (HBV) infection, it is difficult to distinguish acute hepatitis B (AHB) from chronic hepatitis B with an acute flare (CHB-AF) in patients whose prior history of HBV infection has been unknown. The present study aimed to screen laboratory parameters other than immunoglobulin M antibody to hepatitis B core antigen (IgM anti-HBc) to discriminate between the two conditions.
Methods: A retrospective and prospective study was conducted in patients first presenting clinically as HBV-related acute hepatitis to sort out acute self-limited hepatitis B (ASL-HB).
Zhongguo Dang Dai Er Ke Za Zhi
June 2006
Department of Pediatrics, Shanghai No.8 People's Hospital, Shanghai 200233, China.
Objective: This study was designed to investigate the prevalence, clinical characteristics and outcome of upper respiratory infection (URI) caused by Mycoplasma pneumoniae (MP) in children.
Methods: Pharyngeal cultures for MP antibody were performed in 960 children with acute URI. The samples were randomly collected from the outpatient room or emergency room (Observed group).