5 results match your criteria: "Shanghai Ninth People's Hospital of Shanghai Jiaotong University[Affiliation]"
Clinical significance of herpes virus entry mediator expression in hepatitis B virus-related hepatocellular carcinoma.
Oncol Lett
October 2020
Key Laboratory of Carcinogenesis and Cancer Invasion, Department of Liver Surgery and Transplantation, Ministry of Education, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.
Herpes virus entry mediator (HVEM) is overexpressed in several malignancies, including hepatocellular carcinoma (HCC). However, to the best of our knowledge, the clinical significance of HVEM in hepatitis B virus (HBV)-related HCC remains unclear. Thus, the present study aimed to explore the clinical significance of HVEM in HBV-related HCC.
View Article and Find Full Text PDFTRB3 reverses chemotherapy resistance and mediates crosstalk between endoplasmic reticulum stress and AKT signaling pathways in MHCC97H human hepatocellular carcinoma cells.
Oncol Lett
January 2018
Department of Gastroenterology, School of Medicine, Shanghai Ninth People's Hospital of Shanghai Jiaotong University, Shanghai 200011, P.R. China.
Tribbles homolog 3 (TRB3), a type of pseudokinase that contains a consensus serine/threonine kinase catalytic core structure, is upregulated in hepatocellular carcinoma. However, the effect of TRB3 expression in hepatocellular carcinoma and the molecular mechanisms underlying TRB3-mediated effects on tumorigenesis in hepatocellular carcinoma have not been fully elucidated. The present study focused on the effect of TRB3 expression in MHCC97H hepatocellular carcinoma cells and investigated the underlying molecular mechanisms in MHCC97H cells.
View Article and Find Full Text PDFEffect of active arm swing to local dynamic stability during walking.
Hum Mov Sci
February 2016
School of Biomedical Engineering, Shanghai Jiaotong University, Shanghai, China; Engineering Research Center of Digital Medicine and Clinical Translation, Ministry of Education of P.R. China, Shanghai, China; Department of Orthopedic Surgery & Shanghai Key Laboratory of Orthopaedic Implant, Shanghai Ninth People's Hospital of Shanghai Jiaotong University School of Medicine, Shanghai, China. Electronic address:
Arm swing is an essential component in regulating dynamic stability of the whole body during walking, while the contribution of active arm swing to local dynamic stability of different motion segments remains unclear. This study investigated the effects of arm swing under natural arm swing condition and active arm swing condition on local dynamic stability and gait variability of the trunk segments (C7 and T10 joint) and lower extremity joints (hip, knee and ankle joint). The local divergence exponents (λs) and mean standard deviation over strides (MeanSD) of 24 young healthy adults were calculated while they were walking on treadmill with two arm swing conditions at their preferred walking speed (PWS).
View Article and Find Full Text PDFUrocortin 2 stimulates nitric oxide production in ventricular myocytes via Akt- and PKA-mediated phosphorylation of eNOS at serine 1177.
Am J Physiol Heart Circ Physiol
September 2014
Institute of Pharmacology and Clinical Pharmacy, Biochemical and Pharmacological Centre Marburg, Philipps-University of Marburg, Marburg, Germany;
Urocortin 2 (Ucn2) is a cardioactive peptide exhibiting beneficial effects in normal and failing heart. In cardiomyocytes, it elicits cAMP- and Ca(2+)-dependent positive inotropic and lusitropic effects. We tested the hypothesis that, in addition, Ucn2 activates cardiac nitric oxide (NO) signaling and elucidated the underlying signaling pathways and mechanisms.
View Article and Find Full Text PDFNADPH oxidase-2 is a key regulator of human dermal fibroblasts: a potential therapeutic strategy for the treatment of skin fibrosis.
Exp Dermatol
September 2014
Department of Hand and Plastic Surgery, The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital of Shanghai Jiaotong University School of Medicine, Shanghai, China.
Article Synopsis
- The study investigates the role of NADPH oxidase in the effects of TGF-β1 on human skin dermal fibroblasts (HDFs), which are key players in skin fibrosis.
- TGF-β1 was found to induce the expression of NADPH oxidase NOX2 and promote oxidative stress, influencing cell proliferation, migration, and collagen production in HDFs.
- The research suggests that targeting NADPH oxidase, particularly NOX2, could be a potential therapeutic approach for treating skin fibrosis.