17 results match your criteria: "Shanghai Neurosurgical Institute[Affiliation]"

Seizures are a common symptom of craniocerebral diseases, and epilepsy is one of the comorbidities of craniocerebral diseases. However, how to rationally use anti-seizure medications (ASMs) in the perioperative period of craniocerebral surgery to control or avoid seizures and reduce their associated harm is a problem. The China Association Against Epilepsy (CAAE) united with the Trauma Group of the Chinese Neurosurgery Society, Glioma Professional Committee of the Chinese Anti-Cancer Association, Neuro-Oncology Branch of the Chinese Neuroscience Society, and Neurotraumatic Group of Chinese Trauma Society, and selected experts for consultancy regarding outcomes from evidence-based medicine in domestic and foreign literature.

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Background And Objectives: Parkinson's disease (PD) is one of the most common forms of neurodegenerative disorders, and its etiology remains unclear. Single nucleotide polymorphisms (SNPs) of alpha-synuclein (SNCA) have been found to be significantly associated with PD risk. In particular, the variant rs11931074 was found in one meta-analysis to appear to play a role in the occurrence of PD.

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Background: Craniocerebral gunshot injury refers to a wound caused by a bullet passing through or lodged in brain tissue, resulting in the loss of function of a certain area or other fatal damage to the human brain. Craniocerebral gunshot injury is usually life-threatening and is very common in modern warfare, accounting for the majority of battle casualties. Most of the patients suffer from acute cerebral infarction caused by vascular injury.

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We aim to perform a systematic review and meta-analysis to examine the prognostic value of decompressive craniectomy (DC) in patients with traumatic intracranial hypertension. PubMed, EMBASE, Cochrane Controlled Trials Register, Web of Science, http://clinicaltrials.gov/ were searched for eligible studies.

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Presurgical Planning for Supratentorial Lesions with Free Slicer Software and Sina App.

World Neurosurg

October 2017

Department of Neurosurgery, Shanghai Neurosurgical Institute, Changzheng Hospital, Shanghai, China. Electronic address:

Background: Neuronavigation systems are used widely in the localization of intracranial lesions with satisfactory accuracy. However, they are expensive and difficult to learn. Therefore, a simple and practical augmented reality (AR) system using mobile devices might be an alternative technique.

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Cerebral venous sinus thrombosis complicated with acute development of dural arteriovenous fistula: A case report.

J Clin Neurosci

October 2017

Department of Neurosurgery, Shanghai Neurosurgical Institute, Changzheng Hospital, Shanghai, China. Electronic address:

Development of dural arteriovenous fistula (dAVF) after cerebral venous sinus thrombosis (CVST) was very uncommon and for all these reported cases, the dAVF was a chronic complication. We present a case of acute development of dAVF after CVST. A 40-year-old female was admitted into our department with 2day's headache and vomiting for 9h.

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Objective: To explore whether segmentation and 3D modeling are more accurate in the preoperative detection of the neurovascular relationship (NVR) in patients with trigeminal neuralgia (TN) compared to MRI fast imaging employing steady-state acquisition (FIESTA).

Method: Segmentation and 3D modeling using 3D Slicer were conducted for 40 patients undergoing MRI FIESTA and microsurgical vascular decompression (MVD). The NVR, as well as the offending vessel determined by MRI FIESTA and 3D Slicer, was reviewed and compared with intraoperative manifestations using SPSS.

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Article Synopsis
  • The recovery from kidney ischemia/reperfusion (IR) injury involves reducing inflammation and repairing tubular epithelial cells (TECs).
  • IκB kinase α (IKKα) is suggested to play a central role in this process by promoting anti-inflammatory responses and enhancing TEC proliferation and differentiation.
  • Research using a mouse model showed that IKKα facilitates kidney repair through regulatory T (Treg) cells that produce the anti-inflammatory cytokine IL10, highlighting its potential as a therapeutic target for improving kidney recovery post-injury.
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[Surgical treatment of hemangioblastoma in medulla oblongata:a report of 12 cases].

Zhonghua Yi Xue Za Zhi

September 2013

Shanghai Neurosurgical Institute; Department of Neurosurgery, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China.

Objective: To explore the clinical characteristics, diagnostic strategies and surgical techniques of hemangioblastoma (HB) in medulla oblongata.

Methods: The clinical and radiological characteristics, therapeutic processes and outcomes of 12 HB cases treated at our department from 2002 to 2012 were studied by retrospective analysis.

Results: Headache, somatic numbness and limb muscle weakness were the major symptoms of oblongata HB.

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Object: The aim of this study was to provide information about long-term functional outcome in patients with isolated oculomotor nerve palsy following minor head injury and to discuss surgical treatment of these patients, especially those with accompanying sphenoid fracture.

Methods: A retrospective analysis was made of 26 patients with traumatic isolated oculomotor nerve palsy. The severity of oculomotor nerve palsy and the functional recovery were evaluated based on extraocular muscle movement, eyelid movement, and pupil size.

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SPP1 promoter polymorphisms and glioma risk in a Chinese Han population.

J Hum Genet

July 2010

Department of Neurosurgery, Shanghai Neurosurgical Institute, ChangZheng Hospital, Second Military Medical University, Shanghai, China.

SPP1 was found to be significantly upregulated in many kinds of malignant tumors, including gliomas. Considering that gene polymorphisms have been implicated in the development of gliomas, we performed an association study between SPP1 functional promoter region polymorphisms and glioma risk in a Chinese population. We found significant evidence of an association between SPP1 promoter polymorphisms and glioma risk.

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Clinical treatment of traumatic brain injury complicated by cranial nerve injury.

Injury

September 2010

Department of Neurosurgery, Changzheng Hospital, Second Military Medical, University, Shanghai Neurosurgical Institute, 415 Fengyang Road, Shanghai 200003, China.

Objective: To discuss the epidemiology, diagnosis and surgical treatment of cranial nerve injury following traumatic brain injury (TBI) for the sake of raising the clinical treatment of this special category of TBI.

Patients And Methods: A retrospective analysis was made of 312 patients with cranial nerve injury among 3417 TBI patients, who were admitted for treatment in this hospital.

Results: A total of 312 patients (9.

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This study was designed to elucidate the generating mechanism, diagnosis and treatment of traumatic carotid cavernous fistula (tCCF) concomitant with pseudoaneurysm in the sphenoid sinus. Six cases of tCCF concomitant with pseudoaneurysm in the sphenoid sinus were analyzed in this study. Clinical history, neurological examination, CT and MRI scans, pre- and postembolization cerebral angiograms and follow-up data were included.

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A number of factors, including Glasgow coma scale (GCS) score, age, pupillary response and size, hypoxia, hyperthermia, and high intracranial pressure, may play an important role in predicting the outcome of traumatic brain injury. Eight hundred forty-six cases of severe traumatic brain injury (GCS < or = 8) were analyzed retrospectively to clarify the effects of multiple factors on the prognosis of patients. At 1 year after injury, the outcomes in these cases were as follows: good recovery, 31.

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Object: The goal of this study was to investigate the protective effects of long-term (3-14 days) mild hypothermia therapy (33-35 degrees C) on outcome in 87 patients with severe traumatic brain injury (TBI) (Glasgow Coma Scale score < or = 8).

Methods: In 43 patients assigned to a mild hypothermia group, body temperatures were cooled to 33 to 35 degrees C a mean of 15 hours after injury and kept at 33 to 35 degrees C for 3 to 14 days. Rewarming commenced when the individual patient's intracranial pressure (ICP) returned to the normal level.

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