8 results match your criteria: "Shanghai Municipal Center for Diseases Control and Prevention[Affiliation]"
Full-Spectrum Surveillance of Pre-Treatment HIV Drug Resistance in Southeastern China.
Pharmaceuticals (Basel)
July 2024
Department of HIV/AIDS Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
Article Synopsis
- - The study examines pre-treatment drug resistance (PDR) in newly diagnosed HIV-1 individuals in Wenzhou, China, finding a total PDR prevalence of 6.5% for any antiretroviral drug.
- - Among specific drug classes, the highest resistance was noted for non-nucleoside reverse transcriptase inhibitors (NNRTIs) at 4.1%, while resistance rates for nucleoside reverse transcriptase inhibitors (NRTIs), protease inhibitors (PIs), and integrase strand transfer inhibitors (INSTIs) were significantly lower.
- - The findings suggest a need for more non-NNRTI-based ART treatments and emphasize the importance of genotypic resistance testing prior to starting
[Epidemiological characteristics and drug resistance of diarrheagenic infection in diarrhea patients in Shanghai, 2016-2022].
Zhonghua Liu Xing Bing Xue Za Zhi
July 2024
Shanghai Municipal Center for Diseases Control and Prevention, Shanghai 200336, China.
To understand the infection status, epidemiological characteristics and drug resistance of Diarrheagenic (DEC) in Shanghai and provide evidence for the disease surveillance. The epidemiological data of diarrhea cases in Shanghai from 2016 to 2022 were collected from Shanghai Diarrhea Comprehensive Surveillance System, and stool samples were collected from the cases for DEC detection. The drug resistance data was obtained from Chinese Pathogen Identification Network.
View Article and Find Full Text PDFLong-term care facilities (LTCFs) for older people play an important and unique role in multidrug-resistant organism transmission. Herein, we investigated the genetic characteristics of mobile colistin resistance gene ()-carrying strains isolated from wastewater of LTCFs in Shanghai. Antimicrobial susceptibility test was carried out by agar dilution methods.
View Article and Find Full Text PDFEditorial: Advances in the diagnosis and genomic research of surveillance-response activities in emerging, re-emerging, and unidentified infectious diseases.
Front Public Health
June 2023
School of Global Health, Chinese Center for Tropical Diseases Research, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Combining molecular network analysis and field epidemiology to quantify local HIV transmission and highlight ongoing epidemics.
Int J Infect Dis
March 2023
Department of HIV/AIDS Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, China. Electronic address:
Objectives: This study aimed to establish a collaborative approach to quantify local HIV transmission, which is an issue of great concern to public health.
Methods: We linked HIV-1 pol gene sequences to demographic information and epidemiological investigations in Hangzhou (a central city in East China). We estimated local acquisition rates from a collaboration of molecular network analysis (with a distance-based approach) and epidemiological investigations.
Kelch 13 (Pfk13) is an essential protein that contains BTB and Kelch-repeat propeller domains (KRPD), which was predicted to bind substrate during ubiquitin-dependent degradation pathway. However, the function of Pfk13 and the structural alterations associated with artemisinin resistance mutations remain unknown. Herein, we screened two proteins, namely Pfk13-F446I and Pfk13-C580Y, which are closely associated with artemisinin, for structural prediction analysis.
View Article and Find Full Text PDFPhylodynamics of major CRF01_AE epidemic clusters circulating in mainland of China.
Sci Rep
July 2017
Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, 100071, China.
As the most dominant HIV-1 strain in China, CRF01_AE needs to have its evolutionary and demographic history documented. In this study, we provide phylogenetic analysis of all CRF01_AE pol sequences identified in mainland China. CRF01_AE sequences were collected from the Los Alamos HIV Sequence Database and the local Chinese provincial centers of disease control and prevention.
View Article and Find Full Text PDF[Qualitative and quantitative comparison of three agglutination tests for detecting Toxoplasma gondii antibodies].
Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi
September 2003
Shanghai Municipal Center for Diseases Control and Prevention, Shanghai 200031.
Objective: To evaluate the diagnostic value of three agglutination tests used in three countries for detection of antibodies to Taxoplasma gondii.
Methods: A total of 288 human serum samples were assayed using modified agglutination test (MAT-1, using selfmade antigen), latex agglutination test (LAT, using Japanese Kit) and modified agglutination test (MAT-2, using French antigen).
Results: The positive rates of MAT-1 (> or = 1:20), LAT (> or = 1:32) and MAT-2 (> or = 1:20) were 9.