2 results match your criteria: "Shanghai Jiaotong University100 Haining Road[Affiliation]"
Protective effect of asiatic acid in an experimental cerulein-induced model of acute pancreatitis in mice.
Am J Transl Res
August 2017
Department of Gastroenterology, Shanghai Tenth People's Hospital, School of Medicine, Tongji University301 Yanchang Road, Jingan District, Shanghai 200072, People's Republic of China.
Asiatic acid (AA), a triterpenoid derived from the medicinal plant , is considered to have anti-inflammatory, anti-fibrotic and anti-tumor effects, but its effects in acute pancreatitis (AP) are unknown. Our purpose of this study was to investigate the effects of AA in a mouse model of cerulein-induced pancreatitis. We evaluated AA in an experimental model of AP induced in mice by six hourly intraperitoneal injections of cerulein 50 µg/kg.
View Article and Find Full Text PDFDownregulation of miR-301a-3p sensitizes pancreatic cancer cells to gemcitabine treatment via PTEN.
Am J Transl Res
April 2017
Department of General Surgery, Shanghai General Hospital/First People's Hospital, Shanghai Jiaotong University100 Haining Road, Shanghai 200080, China.
Background: We previously showed that miR-301a-3p affects the invasion and migration abilities of pancreatic cancer cells. Here, we explore the role of miR-301a-3p in chemoresistance, which represents a major obstacle in cancer treatment.
Methods: We tested the effects of miR-301a-3p ongemcitabine resistance in cytotoxicity assays and .