1 results match your criteria: "Shanghai Jiaotong University Shanghai 200240 China haifengchen@sjtu.edu.cn +86-21-34204348 +86-21-34204348.[Affiliation]"
Synergistic regulation mechanism of iperoxo and LY2119620 for muscarinic acetylcholine M2 receptor.
RSC Adv
April 2018
State Key Laboratory of Microbial Metabolism, Department of Bioinformatics and Biostatistics, National Experimental Teaching Center for Life Sciences and Biotechnology, College of Life Sciences and Biotechnology, Shanghai Jiaotong University Shanghai 200240 China +86-21-34204348 +86-21-34204348.
Muscarinic acetylcholine receptors are GPCRs that regulate the activity of a diverse array of central and peripheral functions in the human body, including the parasympathetic actions of acetylcholine. The M2 muscarinic receptor subtype plays a key role in modulating cardiac function and many important central processes. The orthosteric agonist and allosteric modulator can bind the pocket of M2.
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