87,227 results match your criteria: "Shanghai Jiao Tong University.[Affiliation]"
Knee Surg Sports Traumatol Arthrosc
December 2024
Department of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Purpose: To explore if recentering the humeral head could improve shoulder abduction in shoulders with irreparable massive rotator cuff tears (IMRCTs).
Methods: Nine fresh-frozen cadaveric shoulders were used to simulate the intact condition and IMRCTs as controls. Four 'recenter' interventions were then sequentially applied: subacromial interposition (SI) using 4- and 8-mm spacers and superior capsule reconstruction (SCR) using two- and four-layer fascia lata grafts.
Commun Med (Lond)
December 2024
Shanghai Jiao Tong University, Shanghai, China.
Background: Medical Visual Question Answering (MedVQA) enhances diagnostic accuracy and healthcare delivery by leveraging artificial intelligence to interpret medical images. This study aims to redefine MedVQA as a generation task that mirrors human-machine interaction and to develop a model capable of integrating complex visual and textual information.
Methods: We constructed a large-scale medical visual-question answering dataset, PMC-VQA, containing 227,000 VQA pairs across 149,000 images that span various modalities and diseases.
Cell Biosci
December 2024
The State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University, Shanghai, 200240, China.
Background: Aberrant interplay between epigenetic reprogramming and metabolic rewiring events contributes to bladder cancer progression and metastasis. How the deacetylase Sirtuin-6 (SIRT6) regulates glycolysis and lactate secretion in bladder cancer remains poorly defined. We thus aimed to study the biological functions of SIRT6 in bladder cancer.
View Article and Find Full Text PDFJ Pain Symptom Manage
December 2024
West China School of Nursing, Sichuan University/West China Hospital, Sichuan University, Chengdu, China. Electronic address:
J Control Release
December 2024
Department of Otolaryngology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China. Electronic address:
Background: Chronic rhinosinusitis (CRS) is an inflammatory disease characterized by persistent immune dysregulation, which presents considerable limitations in current medical therapy.
Objects: This study investigates a supramolecular gel (PSPD), which aims to minimize systemic adverse effects through local injection, provide long-lasting anti-inflammatory effects, and modulate the mucosal immune microenvironment.
Methods: The properties of PSPD were evaluated using rheological experiments.
J Hazard Mater
December 2024
State Key Laboratory of Food Science and Resources, Jiangnan University, No. 1800 Lihu Avenue, Wuxi, Jiangsu Province 214122, China; School of Food Science and Technology, Jiangnan University, No. 1800 Lihu Avenue, Wuxi, Jiangsu Province 214122, China. Electronic address:
Thiram is a readily synthesized, cost-effective antimicrobial agent widely used to control diseases in fruits and vegetables. Given the potential health hazards associated with thiram residues and advancements in detection methods, it is crucial to develop a rapid and sensitive technique for detecting these residues on fruit surfaces. Here, we prepared the Ag@filter paper (Ag@FP) surface-enhanced Raman scattering (SERS) substrate in a controlled manner and innovatively developed a capillarity-assisted SERS (CA-SERS) detection method.
View Article and Find Full Text PDFEBioMedicine
December 2024
Center for Reproductive Medicine, Shandong University, Jinan, Shandong, 250012, China; Key Laboratory of Reproductive Endocrinology of Ministry of Education, Shandong University, Jinan, Shandong, 250012, China; Shandong Key Laboratory of Reproductive Medicine, Jinan, Shandong, 250012, China; Shandong Provincial Clinical Research Center for Reproductive Health, Jinan, Shandong, 250012, China; Shandong Technology Innovation Center for Reproductive Health, Jinan, Shandong, 250012, China; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Shandong University, Jinan, Shandong, 250012, China; Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China. Electronic address:
Background: Preimplantation genetic testing for chromosomal structural rearrangements (PGT-SR) has been widely utilized to select euploid embryos in patients carrying balanced chromosomal rearrangements (BCRs) by chromosome copy number analysis. However, reliable and extensively validated PGT-SR methods for selecting embryos without BCRs in large-cohort studies are lacking.
Methods: In this prospective, multicenter, cohort study, carriers with BCRs undergoing PGT-SR were recruited across 12 academic fertility centers within China.
Curr Opin Microbiol
December 2024
State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai, China; Department of Bioengineering, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, China; Wuhan Hesheng Technology Co., Ltd, Wuhan, China. Electronic address:
As a class of natural compounds ubiquitous in nature, diverse terpenoids exhibit a broad spectrum of applications in human endeavors. The efficient discovery of novel terpenoids and the establishment of a terpene library for broad utilization represent pressing challenges in terpenoid natural product research. Various microbial platforms offer abundant precursors for terpene biosynthesis from diverse sources.
View Article and Find Full Text PDFClin Exp Med
December 2024
Department of Biliary-Pancreatic Surgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200127, People's Republic of China.
Pancreatic cancer (PC) is a malignancy of the gastrointestinal tract that is characterized by a poor prognosis. This study investigates the roles of immunogenic cell death (ICD) genes in the prognosis and progression of PC. Expression data for PC patients were obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets, while ICD genes were sourced from published literature.
View Article and Find Full Text PDFJACC Cardiovasc Interv
October 2024
Seoul National University Hospital, Seoul, Republic of Korea. Electronic address:
Thorac Cancer
December 2024
Department of Thoracic Surgery, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Introduction: To identify high-risk patients for recurrence in resected stage IA lung adenocarcinoma and evaluate the impact of adjuvant chemotherapy (ACT) on their prognosis, as well as explore potential novel adjuvant therapies.
Methods: Consecutive stage IA patients with ≥ 5% solid or micropapillary subtypes were analyzed. A nomogram was developed using Cox proportional hazards regression to predict recurrence-free survival (RFS).
Mol Plant Pathol
December 2024
Shanghai Center for Plant Stress Biology, Center for Excellence in Molecular Plant Sciences, Chinese Academy of Sciences, Shanghai, China.
Microbial pathogens and other parasites can modify the development of their hosts, either as a target or a side effect of their virulence activities. The plant-pathogenic bacterium Ralstonia solanacearum, causal agent of the devastating bacterial wilt disease, is a soilborne microbe that invades host plants through their roots and later proliferates in xylem vessels. In this work, we studied the early stages of R.
View Article and Find Full Text PDFAdv Mater
December 2024
School of Chemistry, Engineering Research Center of Energy Storage Materials and Devices, Ministry of Education, National Innovation Platform (Center) for Industry-Education Integration of Energy Storage Technology, Engineering Research Center of Energy Storage Material and Chemistry, Universities of Shaanxi Province, Xi'an Jiaotong University, Xi'an, 710049, China.
Direct recycling technology can effectively solve the environmental pollution and resource waste problems caused by spent lithium-ion batteries. However, the repaired LiNiCoMnO (NCM) black mass by direct recycling technology shows an unsatisfactory cycle life, which is attributed to the formation of spinel/rock salt phases and rotational stacking faults caused by the in-plane and out-of-plane migration of transition metal (TM) atoms during charge/discharge. Herein, local lattice stress is introduced into the regenerated cathode during repair.
View Article and Find Full Text PDFSmall
December 2024
School of Life Sciences, Shanghai University, Shanghai, 200444, P. R. China.
Plasmonic metasurfaces (PMs) exhibit extraordinary optical response due to surface lattice resonance, which is crucial for realizing high-performance photovoltaic device preparation. In this work, a nanopore confinement effect-mediated MOF@UsAu is proposed as a novel PM heterojunction for photovoltaic interfaces. 2D MOFs have the unique advantage of a tunable and ordered porous structure.
View Article and Find Full Text PDFDiabetol Metab Syndr
December 2024
Department of Endocrinology and Metabolism, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No.160 Pujian Road, Shanghai, 200127, China.
Aims: To observe the effects of liraglutide on abdominal fat distribution in Chinese subjects with obesity in 12 weeks, and further to explore the correlation between abdominal fat content and glucose metabolism after monotherapy.
Methods: This study recruited 71 obese subjects. All the subjects have received liraglutide monotherapy (0.
Cancer Imaging
December 2024
Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Pujian Road 160, Pudong District, 200127, Shanghai, China.
Background: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. Recent advent of tyrosine kinase inhibitors (TKIs) has significantly improved the prognosis of GIST patients. However, responses to TKI therapy can vary depending on the specific gene mutation.
View Article and Find Full Text PDFClin Epigenetics
December 2024
School of Life and Pharmaceutical Sciences, Dalian University of Technology, Panjin, China.
J Transl Med
December 2024
Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Background: Yes-associated protein 1 (YAP1) regulates the survival, proliferation, and stemness of cells, and contributes to the development of metabolic dysfunction associated fatty liver disease (MAFLD). However, the regulatory role of intestinal YAP1 in MAFLD still remains unclear.
Methods: Terminal ileal specimens were used to compare intestinal YAP1 activation in patients with and without MAFLD.
BMC Urol
December 2024
Department of Andrology, the Center for Men's Health, Shanghai General Hospital, Urologic Medical Center, Shanghai Jiao Tong University, Shanghai, 200080, China.
Background: Vasoepididymostomy (VE) is an important surgical treatment to achieve natural conception for patients with obstructive azoospermia (OA), and only unilateral VE can be performed under certain conditions, such as OA patients with congenital unilateral absence of the vas deferens (CUAVD) and some acquired OA. There is a lack of relevant reports assessing the clinical outcomes of unilateral VE in OA patients with different causes. This study is aimed to describe the clinical features and evaluate treatments and outcomes of unilateral single-armed VE in OA patients.
View Article and Find Full Text PDFEnviron Health
December 2024
Department of Pediatric Cardiology, School of Medicine, Xinhua Hospital, Shanghai Jiao Tong University, NO1665 Kongjiang Road, Shanghai, 200092, China.
Background: Congenital heart disease (CHD) is a common birth defect. Our previous studies suggest that indoor air pollution, especially total volatile organic compounds (TVOCs), may increase fetal CHD risk, whereas vitamin and folic acid (FA) supplements in early pregnancy might offer protection against CHD. However, limited research has explored whether FA or multivitamin supplementation can mitigate the effects of TVOCs exposure on CHD.
View Article and Find Full Text PDFBMC Genomics
December 2024
School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dongchuan Road, Shanghai, 200240, China.
Background: The diversity-generating retroelements (DGRs) are a family of genetic elements that can produce mutations in target genes often related to ligand-binding functions, which possess a C-type lectin (CLec) domain that tolerates massive variations. They were first identified in viruses, then in bacteria and archaea from human-associated and environmental genomes. This DGR mechanism represents a fast adaptation of organisms to ever- changing environments.
View Article and Find Full Text PDFMol Neurobiol
December 2024
Department of Pediatrics, the Second School of Medicine, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
White matter injury (WMI) is a common complication of preterm birth, potentially resulting in long-term behavioral and motor abnormalities. The objective of this study is to investigate the neuroprotective effects of glycyrrhizin (GLY) on WMI, and try to elucidate the potential mechanisms. In vivo chronic hypoxia-induced WMI mouse model and in vitro oxygen-glucose deprivation (OGD) induced WMI cell model were established, and the effects of GLY on WMI were explored through multiple assays, such as western blotting, immunofluorescence, immunohistochemistry, behavioral experiments, real-time quantitative polymerase chain reaction (RT-qPCR), transmission electron microscope (TEM), molecular docking, and bioinformatics analysis.
View Article and Find Full Text PDFBone Marrow Transplant
December 2024
Department of Hematology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China.
In this real-world study, 153 adult T-cell lymphoblastic lymphoma (T-LBL) patients from sixteen centers in Shanghai were enrolled. Out of them, 103 (67.3%) achieved complete remission (CR).
View Article and Find Full Text PDFCell Death Dis
December 2024
Department of Otolaryngology, Head and Neck Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Prog Neuropsychopharmacol Biol Psychiatry
December 2024
Department of Psychology and Behavioral Sciences, Zhejiang University, Hangzhou, China. Electronic address:
Social functioning impairment is a core symptom of schizophrenia (SCZ). Yet, the computational and neural mechanisms of social coordination in SCZ under real-time and naturalistic settings are poorly understood. Here, we instructed patients with SCZ to coordinate with a healthy control (HC) in a joint finger-tapping task, during which their brain activity was measured by functional near-infrared spectroscopy simultaneously.
View Article and Find Full Text PDF