2 results match your criteria: "Shanghai Jiao Tong University School of Medicine 200240 Shanghai[Affiliation]"

SERPINA3 promotes endometrial cancer cells growth by regulating G2/M cell cycle checkpoint and apoptosis.

Int J Clin Exp Pathol

February 2015

State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine 200240 Shanghai, P.R. China.

Endometrial carcinoma (EC) is the most common gynecologic cancer worldwide and is one of the leading causes of death in women. Therefore, it is urgent to elucidate the pathological mechanisms of EC. SERPINA3 is a member of the serpin super-family of protease inhibitors.

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Dysregulated cell mechanical properties of endometrial stromal cells from endometriosis patients.

Int J Clin Exp Pathol

October 2014

Obstetrics and Gynecology Hospital, Fudan University Shanghai 200011, People's Republic of China ; Shanghai Key Laboratory of Female Reproductive Endocrine Related Diseases Shanghai 200011, China ; Department of Obstetrics and Gynecology of Shanghai Medical College, Fudan University Shanghai 200032, China ; Institutes of Biomedical Sciences, Fudan University Shanghai 200032, People's Republic of China.

Endometriosis, diagnosed with ectopically implanted endometrial stromal cells (ESC) and epithelial cells to a location outside the uterine cavity, seriously threaten the quality of life and reproductive ability of women, yet the mechanisms and the pathophysiology of the disease remain unclear. Specially, the functional changes of ESC during endometriosis progression need in-depth investigation. In this study, we characterized mechanical properties of normal ESC (NESC) from healthy women and eutopic ESC (EuESC) and ectopic ESC (EcESC) from endometriosis patients.

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