7 results match your criteria: "Shanghai Jiao Tong University Affiliated Ruijin Hospital[Affiliation]"
Diagnostic performance of fully automatic coronary CT angiography-based quantitative flow ratio.
J Cardiovasc Comput Tomogr
October 2024
Biomedical Instrument Institute, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, China; Department of Cardiology, Erasmus MC Medical University, Rotterdam, the Netherlands; Institute of Medical Robotics, Shanghai Jiao Tong University, Shanghai, China. Electronic address:
Article Synopsis
- A new method called CT-μFR, based on automatic CCTA reconstruction, was developed to identify significant coronary artery blockages using artificial intelligence, showing favorable accuracy when compared to traditional tests in the cath lab.
- This study analyzed data from the CAREER trial, where 657 vessels from 242 patients were evaluated for diagnostic accuracy and correlation with established physiological standards for determining significant stenosis.
- Results showed that CT-μFR effectively identified patients with serious blockages, achieving an accuracy rate of 83.0%, with a short average analysis time of around 1.6 minutes per patient, indicating its potential for clinical use.
Bioinformatics analysis identifies potential ferroptosis key genes in the pathogenesis of diabetic peripheral neuropathy.
Front Endocrinol (Lausanne)
June 2023
Department of Anesthesiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Background: Diabetic peripheral neuropathy (DPN) is a serious complication in Diabetes Mellitus (DM) patients and the underlying mechanism is yet unclear. Ferroptosis has been recently intensively researched as a key process in the pathogenesis of diabetes but there yet has been no related bioinformatics-based studies in the context of DPN.
Methods: We used data mining and data analysis techniques to screen differentially expressed genes (DEGs) and immune cell content in patients with DPN, DM patients and healthy participants (dataset GSE95849).
Effects of advanced glycation end products on neutrophil migration and aggregation in diabetic wounds.
Aging (Albany NY)
April 2021
Department of Burn, Shanghai Jiao Tong University Affiliated Ruijin Hospital, Shanghai, China.
Article Synopsis
- * Elevated AGEs primarily affect skin tissues, hindering neutrophil migration and adhesion as AGE concentrations reach critical levels.
- * Molecular analysis indicates that specific proteins (PVR/CD155 and CTNND1) involved in neutrophil functions are reduced after AGE exposure, impairing the inflammatory response needed to clear damaged tissues and fight infections in diabetic wounds.
The handheld ultrasound demonstrates clinical and economic value in combating COVID-19 based on interviews with frontline ultrasound physician and cardiologist as well as a national expert in medical ultrasound.
View Article and Find Full Text PDFDecellularized Versus Fresh-Frozen Allografts in Anterior Cruciate Ligament Reconstruction: An In Vitro Study in a Rabbit Model.
Am J Sports Med
August 2015
Department of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China
Background: The common fresh-frozen allografts that are used for anterior cruciate ligament (ACL) reconstructions behave slower during the remodeling process and produce weaker tendon-bone integrations than do autografts. Decellularization of allogenic tendons results in a clean and porous collagen scaffold with low antigenicity and high compatibility, which may be more suitable for ACL reconstructions.
Hypothesis: Allograft decellularization will result in a tissue structure with suitable mechanical characteristics for ACL reconstruction, thereby promoting graft remodeling and enhancing tendon-bone healing.
Open reduction and internal fixation of Ideberg IV and V glenoid intra-articular fractures through a Judet approach: a retrospective analysis of 11 cases.
Arch Orthop Trauma Surg
February 2015
Department of Orthopaedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.
Objectives: To evaluate the methods and the outcomes of complex intra-articular glenoid fractures, treated by open reduction and internal fixations.
Methods: The outcomes of 11 cases of complex intra-articular glenoid scapular fractures were retrospectively analyzed. The fractures were classified as type IV in five cases, type Va in two and Vb in four cases, according to Ideberg classification system.
[Comparative analysis of decitabine combined with DAG regimen and other regimens in treatment of refractory/relapsed acute myeloid leukemia].
Zhonghua Xue Ye Xue Za Zhi
June 2014
Department of Hematology, Shanghai Jiao-Tong University Affiliated Ruijin Hospital, Shanghai 200025, China.
Objective: To compare the clinical efficacy and safety among different chemotherapeutic regimens in treatment of refractory/relapsed acute myeloid leukemia (AML).
Methods: The clinical data of 67 refractory/relapsed AML patients enrolled from September 2008 to April 2013 were collected. The differences of clinical outcome and adverse events among the patients treated with decitabine combined with DAG regimen, CAG regimen or "3+7" regimen were analyzed.