4 results match your criteria: "Shanghai Institutes for Biological Sciencesgrid.419092.7[Affiliation]"

Large-Scale Studies on Antimicrobial Resistance and Molecular Characterization of Escherichia coli from Food Animals in Developed Areas of Eastern China.

Microbiol Spectr

August 2022

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, Zhejiang, China.

Widely distributed multidrug-resistant (MDR) bacteria threaten animals and human health. Nevertheless, few antimicrobial resistance (AMR) surveys of large-scale animal-derived bacteria have been explored. Here, 1,468 (97.

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Escherichia fergusonii, an Underrated Repository for Antimicrobial Resistance in Food Animals.

Microbiol Spectr

February 2022

CAS Key Laboratory of Synthetic Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciencesgrid.419092.7, Chinese Academy of Sciences, Shanghai, China.

A total of 1,400 samples of food animals (pigs, chickens, and ducks) were collected between July and September 2019 in China to uncover the prevalence of and its potential role in the evolution of antimicrobial resistance (AMR). An isolation of was performed and pulsed-field gel electrophoresis (PFGE) was used to uncover the genetic relationship. The AMR of isolates was comprehensively characterized using broth microdilution-based antimicrobial susceptibility testing, S1-PFGE, southern hybridization, whole-genome sequencing, and in-depth bioinformatics analysis.

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Putative Familial Transmissible Bacteria of Various Body Niches Link with Home Environment and Children's Immune Health.

Microbiol Spectr

December 2021

CAS Key Laboratory of Computational Biology, Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, People's Republic of China.

Owing to their significant impact on children's long-term health, familial factors in the microbiomes of children have attracted increasing attention. However, the mechanism underlying microbiome transmission across generations remains unclear. A significantly lower alpha diversity was observed in the gut flora of children than in the gut flora of parents and grandparents; the alpha diversity of oral and skin microbiota was relatively higher in children than in their predecessors.

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Comparison of Fecal Collection Methods on Variation in Gut Metagenomics and Untargeted Metabolomics.

mSphere

October 2021

State Key Laboratory of Genetic Engineering School of Life Sciences, Human Phenome Institute, Fudan Universitygrid.8547.e, Shanghai, China.

Article Synopsis
  • - The study explores how different fecal collection methods affect metagenomics and metabolomics in understanding gut microbe-human interactions, using six collection methods on samples from healthy volunteers.
  • - Most collection methods (OMNIgene Gut, FOBT cards, RNAlater, and Microlution) showed high reliability for gut metagenomic studies, while 95% ethanol excelled in preserving metabolite profiles.
  • - The findings suggest that using separate methods for metagenomic sequencing and metabolomic profiling is crucial for accurate results in large-scale research on gut microbiomes.
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