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Evolution of the vertebrate Y RNA cluster.
Theory Biosci
August 2007
Department of Combinatorics and Geometry (DCG), CAS/MPG Partner Institute for Computational Biology (PICB), Shanghai Institutes for Biological Sciences (SIBS) Campus, Shanghai, China.
Relatively little is known about the evolutionary histories of most classes of non-protein coding RNAs. Here we consider Y RNAs, a relatively rarely studied group of related pol-III transcripts. A single cluster of functional genes is preserved throughout tetrapod evolution, which however exhibits clade-specific tandem duplications, gene-losses, and rearrangements.
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