5 results match your criteria: "Shanghai Institute of Infectious Disease and Biosecurity Fudan University[Affiliation]"
Effects of Long-Term Exposure to Ambient Formaldehyde on Hypertension and Angina Pectoris Symptoms: Evidence From the WHO SAGE Cohort Study.
J Am Heart Assoc
October 2024
Department of Public Health and Preventive Medicine, School of Medicine Jinan University Guangzhou China.
Background: We aimed to investigate the associations of long-term exposure to ambient formaldehyde with hypertension and angina pectoris symptoms in Chinese adults.
Methods And Results: Participants' information was obtained from the WHO SAGE (World Health Organization Study on Global Aging and Adult Health) study. The Cox proportional hazards regression model was applied to estimate the associations of formaldehyde with hypertension and angina pectoris symptoms.
Peptide-TLR7/8a-Coordinated DNA Vaccines Elicit Enhanced Immune Responses against Infectious Diseases.
ACS Biomater Sci Eng
July 2024
Key Laboratory of Medical Molecular Virology of MOE/NHC/CAMS, School of Basic Medical Sciences, Shanghai Institute of Infectious Disease and Biosecurity Fudan University, Shanghai 200032, China.
DNA vaccines represent an innovative approach for the immunization of diverse diseases. However, their clinical trial outcomes are constrained by suboptimal transfection efficiency and immunogenicity. In this work, we present a universal methodology involving the codelivery of Toll-like receptor 7/8 agonists (TLR7/8a) and antigen gene using TLR7/8a-conjugated peptide-coated poly(β-amino ester) (PBAE) nanoparticles (NPs) to augment delivery efficiency and immune response.
View Article and Find Full Text PDFLianhua Qingke ameliorates lipopolysaccharide-induced lung injury by inhibiting neutrophil extracellular traps formation and pyroptosis.
Pulm Circ
October 2023
Department of Pulmonary and Critical Care Medicine, Shanghai Respiratory Research Institute, Zhongshan Hospital Fudan University Shanghai China.
LHQK is a patented Traditional Chinese Medicine (TCM) which is clinically used for acute tracheobronchitis, cough, and other respiratory diseases. Recent studies have proved that LHQK exhibits excellent clinical efficacy in the treatment of acute lung injury (ALI). However, the corresponding mechanisms remain largely unexplored.
View Article and Find Full Text PDFEpidemiological and clinical characteristics of respiratory syncytial virus and influenza infections in hospitalized children before and during the COVID-19 pandemic in Central China.
Influenza Other Respir Viruses
February 2023
School of Public Health Fudan University, Key Laboratory of Public Health Safety, Ministry of Education Shanghai China.
Article Synopsis
- The study examined how the COVID-19 pandemic and the use of non-pharmacological interventions (NPIs) affected the rates of respiratory syncytial virus (RSV) and influenza infections in pediatric patients in central China.
- Researchers found that children hospitalized for these infections during the pandemic were older compared to those before it, with RSV cases seeing a decline in severe cases.
- While influenza positivity rates decreased significantly during the pandemic, RSV infections actually increased, highlighting the need for better prevention strategies for childhood RSV.
The traditional Chinese patented medicine Qingke Pingchuan granules alleviate acute lung injury by regenerating club cells.
Pulm Circ
July 2022
Department of Pulmonary and Critical Care Medicine, Shanghai Respiratory Research Institute, Zhongshan Hospital Fudan University Shanghai China.
Qingke Pingchuan granules (QKPCG), a patented traditional Chinese medicine, clinically, are recommended for acute tracheobronchitis, cough, community-acquired pneumonia, and other respiratory diseases. However, its potential protective effect and mechanism of action in acute lung injury (ALI) have not been explored. We aimed to explore the mechanisms underlying the protective role of QKPCG in ALI.
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