5 results match your criteria: "Shanghai Eye Research Institute[Affiliation]"
Safety of repeated low-level red-light therapy for myopia: A systematic review.
Asia Pac J Ophthalmol (Phila)
December 2024
Center for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, VIC, Australia; Research Centre for SHARP Vision (RCSV), The Hong Kong Polytechnic University, Kowloon, Hong Kong, China. Electronic address:
Purpose: Establishing the safety profile of repeated low-level red-light (RLRL) therapy is necessary prior to its widespread clinical implementation.
Methods: We conducted a systematic review (International Prospective Register of Systematic Reviews, CRD42024516676) of articles across seven databases from inception through February 10, 2024, with keywords related to myopia and RLRL therapy. Pooled safety outcomes and risk-to-benefit ratios were reported, and incidence of side effects was compared with other antimyopia interventions.
Wnt5a/β-catenin-mediated epithelial-mesenchymal transition: a key driver of subretinal fibrosis in neovascular age-related macular degeneration.
J Neuroinflammation
March 2024
Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Neovascular age-related macular degeneration (nAMD), accounts for up to 90% of AMD-associated vision loss, ultimately resulting in the formation of fibrotic scar in the macular region. The pathogenesis of subretinal fibrosis in nAMD involves the process of epithelial-mesenchymal transition (EMT) occurring in retinal pigment epithelium (RPE). Here, we aim to investigate the underlying mechanisms involved in the Wnt signaling during the EMT of RPE cells and in the pathological process of subretinal fibrosis secondary to nAMD.
View Article and Find Full Text PDFGlucose transport, transporters and metabolism in diabetic retinopathy.
Biochim Biophys Acta Mol Basis Dis
March 2024
Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China; National Clinical Research Center for Eye Diseases; Shanghai Clinical Research Center for Eye Diseases; Shanghai Key Clinical Specialty; Shanghai Key Laboratory of Ocular Fundus Diseases; Shanghai Engineering Center for Visual Science and Photomedicine; Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China. Electronic address:
Diabetic retinopathy (DR) is the most common reason for blindness in working-age individuals globally. Prolonged high blood glucose is a main causative factor for DR development, and glucose transport is prerequisite for the disturbances in DR caused by hyperglycemia. Glucose transport is mediated by its transporters, including the facilitated transporters (glucose transporter, GLUTs), the "active" glucose transporters (sodium-dependent glucose transporters, SGLTs), and the SLC50 family of uniporters (sugars will eventually be exported transporters, SWEETs).
View Article and Find Full Text PDFProperties of electrically evoked potentials activated by optic nerve stimulation with penetrating electrodes of different modes in rabbits.
Graefes Arch Clin Exp Ophthalmol
December 2015
School of Biomedical Engineering, Shanghai Jiao Tong University, 800 Dongchuan RD, Minhang District, Shanghai, 200240, China.
Purpose: To investigate the effect of different stimulation modes on cortical electrically evoked potentials (EEPs) by intraorbital optic nerve (ON) stimulation with penetrating electrodes.
Methods: A stimulating electrode array with three electrodes arranged linearly was inserted into the ON along its axis. EEPs were recorded using a 4 × 4 silver-ball electrode array in response to monopolar and bipolar stimulation mode, respectively.
Optical coherence tomography measurements of retinal nerve fiber layer thickness in chinese children and teenagers.
J Glaucoma
October 2011
Department of Ophthalmology, Shanghai Eye Research Institute, First People's Hospital of Shanghai, Shanghai Jiaotong University, Shanghai, PR China.
Purpose: To establish a reference range of retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT) in Chinese children and teenagers, and to investigate its relationship with sex, age, eye side, and refractive error.
Methods: A total of 398 eyes from 199 normal Chinese aged 5 to 18 years (a mean of 10.4 ± 2.