1 results match your criteria: "Shanghai Chinese Medical Hospital[Affiliation]"
Norcantharidin anti-angiogenesis activity possibly through an endothelial cell pathway in human colorectal cancer.
Asian Pac J Cancer Prev
September 2012
Department of Oncology, Shanghai Chinese Medical Hospital, Shanghai, China.
Article Synopsis
- The study discovered that norcantharidin has anti-angiogenesis effects on human colon cancer, which was previously unexpected.
- Researchers used a tumor xenograft model in nude mice and confirmed that norcantharidin (5 or 15 mg/kg) inhibits angiogenesis in vivo.
- In vitro experiments showed that norcantharidin reduced the migration, adhesion, and tube formation abilities of human umbilical vein endothelial cells (HUVECs), impacting the expression of key proteins involved in angiogenesis.