Construction of a Au@MoS composite nanosheet biosensor for the ultrasensitive detection of a neurotransmitter and understanding of its mechanism based on DFT calculations.

MoS nanosheets can be applied as electrochemical biosensors to selectively and sensitively respond to the surrounding environment and detect various biomolecules due to their large specific surface area and unique physicochemical properties. In this paper, single-layer or few-layer MoS nanosheets were prepared by an improved liquid phase stripping method, and then combining the unique material characteristics of MoS and the metallic property of Au nanoparticles (AuNPs), Au@MoS composite nanosheets were synthesized based on MoS nanosheets. Then, the structure and properties of MoS nanosheets and Au@MoS composite nanosheets were comprehensively characterized.