2 results match your criteria: "Shandong University Jinan 250117[Affiliation]"

The purpose of this study was to investigate the association between the expression of programmed cell death ligand 1 (PD-L1) and the survival of patients with small cell lung cancer (SCLC) who had undergone complete resection. Formalin-fixed, paraffin-embedded tumor tissue samples from 61 patients with resected SCLC were stained with an anti-PD-L1 antibody (SP142) by immunohistochemistry (IHC) and scored according to staining intensity and the percentage of tumor cells staining positive for PD-L1. The PD-L1 positive threshold in tumor cells was defined as ≥ 5%.

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Article Synopsis
  • * The study showed that lower miR-153 expression is associated with more advanced clinical stages, worse lymph node involvement, increased distant metastasis, and poorer differentiation in NSCLC patients.
  • * Kaplan-Meier survival analysis suggested that patients with lower miR-153 levels have significantly worse overall survival rates, indicating that it could serve as an independent prognostic factor for NSCLC.
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