Traditional hydrogels often face rapid drug release issues due to hydrolysis under acidic conditions, necessitating improved methods for better drug release control.
A new dual-network, pH-responsive biopolysaccharide hydrogel has been created that is self-healing, injectable, and biocompatible, allowing for superior tuneability in drug release.
The study showed that this hydrogel can extend drug release duration by four times compared to simpler versions, with adjustments in sodium alginate content significantly enhancing its release properties.