1 results match your criteria: "Shandong Provincial Research Institute of Family Planning Science and Technology[Affiliation]"
[Association between parental MTHFR gene polymorphism 677C/T and nonsyndromic cleft lip and palate in offspring].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
August 2012
Shandong Provincial Research Institute of Family Planning Science and Technology, Jinan, Shandong, People's Republic of China.
Objective: To explore the association between parental genetic polymorphism of methylenetetrahydrofolate reductase (MTHFR) 677C/T and occurrence of nonsyndromic cleft lip with or without cleft palate (NSCL/P) in offspring in Shandong Province.
Methods: MTHFR genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Parents of 89 NSCL/P patients treated at Qilu Hospital from August, 2006 to August, 2008 and those of 64 healthy children were recruited in this case-control study.