An Integrated Strategy for Rapid Discovery and Identification of Quality Markers in Gardenia Fructus Using an Omics Discrimination-Grey Correlation-Biological Verification Method.

Gardenia Fructus (GF), a traditional Chinese medicine of in Rubiaceae family, has the potential to clear heat and purge fire and has been widely used to treat multiple infection-related diseases. However, the quality markers (Q-Markers) of GF have not been revealed comprehensively. In this experiment, the transgenic zebrafish lines, and were used to evaluate two main kinds of traditional efficacies of GF, hepatoprotective and anti-inflammatory effects.