Crack Sensing of Cardiomyocyte Contractility with High Sensitivity and Stability.

Measuring myocardial contractility is of great value in exploring cardiac pathogenesis and quantifying drug efficacy. Among the biosensing platforms developed for detecting the weak contractility of a single layer of cardiomyocytes (CMs), thin brittle metal membrane sensors with microcracks are highly sensitive. However, their poor stability limits the application in long-term measurement.

Green Manufacturing of Flexible Sensors with a Giant Gauge Factor: Bridging Effect of CNT and Electric Field Enhancement at the Percolation Threshold.

Toxic organic solvents are commonly used to disperse nanomaterials in the manufacturing of flexible conductive composites (e.g., graphene-PDMS).

Fabrication of a Free-Standing MWCNT Electrode by Electric Field Force for an Ultra-Sensitive MicroRNA-21 Nano-Genosensor.

Abnormal expression of microRNA-21 (miR-21) is considered to be closely associated with the pathogenesis of colorectal cancer. However, great challenges do exist for the development of ultra-sensitive biosensors to detect the abnormal expression of miR-21 due to the low concentration in serum (fm level) at the early stage of colorectal cancer. Therefore, electric field force is used to rotate and rearrange random multi-walled carbon nanotubes (MWCNTs) at the microscale to improve the active sites of the electrode in this study.

Damage Evolution of Hot Stamped Boron Steels Subjected to Various Stress States: Macro/Micro-Scale Experiments and Simulations.

Hot stamping components with tailored mechanical properties have excellent safety-related performance in the field of lightweight manufacturing. In this paper, the constitutive relation and damage evolution of bainite, martensite, and mixed bainite/martensite (B/M) phase were studied. Two-dimensional representative volume element (RVE) models were constructed according to microstructure characteristics.

On the Machinability Evolution in Asymmetric Milling of TC25 Ti Alloy Aiming at High Performance Machining.

In this paper, the evolutions of cutting force, cutting temperature, and surface roughness, and the corresponding machinability in asymmetric up-milling of TC25 alloy are investigated. The results indicated that radial depth of cut generated opposite influence on the cutting force/cutting temperature versus surface roughness. The reason can be accounted as the intertwining of feed marks at low radial depth of cut, and the mechanism of hard cutting at a high radial depth of cut.

Electrochemical strategies for the detection of cTnI.

Acute myocardial infarction (AMI) is the main cause of death from cardiovascular diseases. Thus, early diagnosis of AMI is essential for the treatment of irreversible damage from myocardial infarction. Traditional electrocardiograms (ECG) cannot meet the specific detection of AMI.