2 results match your criteria: "Shandong First Medical Universityand[Affiliation]"
Multimodal apparent diffusion MRI model in noninvasive evaluation of breast cancer and Ki-67 expression.
Cancer Imaging
October 2024
Department of Radiology, Shandong Provincial Qianfoshan Hospital, Shandong University, No.16766 Jingshi Road, Jinan, Shandong, China.
Article Synopsis
- - The study investigates how multimodal apparent diffusion (MAD) weighted MRI can differentiate between malignant and benign breast lesions, as well as predict Ki-67 expression levels in breast cancer patients.
- - In a sample of 93 patients, MAD imaging yielded significant differences in parameters between lesion types, with combined parameters showing improved diagnostic performance (AUC of 0.851 for malignancy and 0.691 for Ki-67 levels).
- - Results suggest that MAD weighted MRI is effective for diagnosing breast lesions and predicting Ki-67 expression, which can aid in treatment planning.
Tumor endothelium-derived PODXL correlates with immunosuppressive microenvironment and poor prognosis in cervical cancer patients receiving radiotherapy or chemoradiotherapy.
Biomark Res
September 2024
Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical Universityand, Shandong Academy of Medical Sciences , Jinan, China.
Article Synopsis
- PODXL is a protein found in tumor cells, especially in cervical cancer, but its exact role in cancer growth after treatment is not clear.
- Researchers studied samples from 180 cervical cancer patients and found that PODXL is mostly present in special blood vessel cells called tumor endothelial cells (TECs).
- Higher levels of PODXL in these cells were linked to worse survival rates for patients after they received radiation or chemotherapy, suggesting that targeting PODXL could help in treatment.