174 results match your criteria: "Shamir Medical Center Assaf Harofeh[Affiliation]"

In response to the COVID-19 pandemic, Israel prioritized pregnant women for vaccination, recognizing them as a high-risk group. This study aims to explore factors influencing the acceptance of Influenza, Pertussis (T-dap), and COVID-19 vaccines among pregnant women, focusing on attitudes, social norms, perceived control, and risk perceptions. Additionally, the study compares acceptance patterns between traditional vaccines and the newer COVID-19 vaccine.

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Study Objective: To determine the association of repeat polypectomy with patient and/or polyp characteristics, surgical setting, and type of hysteroscopic equipment.

Methods: Retrospective cohort study including all women who had undergone operative hysteroscopy for the removal of endometrial polyps between 1/2012-12/2022 in our division. Operative hysteroscopy with resection of endometrial polyps was performed using a bipolar loop resectoscope, miniaturized hysteroscopic instruments (bipolar needle, scissors, and graspers), or a tissue-removal device (from April 2021), with or without general anesthesia.

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Article Synopsis
  • The study investigates the link between weakness or dysfunction of the vastus medialis oblique muscle (VMO) and patellar instability, emphasizing that while VMO issues are known in patellofemoral pain syndrome, their role in lateral patellar instability is less clear.
  • Researchers analyzed VMO characteristics in 204 participants, using MRI to measure features like muscle elevation, cross-sectional area (CSA), and fiber angulation, finding that those with patellar instability showed significant differences in these measurements compared to controls.
  • Results indicated that patients with patellar instability had increased muscle elevation and fiber angulation, reduced CSA, and a lower CSA-to-thigh circumference ratio, with recurrent instability showing even more pronounced V
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Objective: This systematic review and meta-analysis compared minimally invasive surgery (MIS) to open surgery for treatment of spinal metastases with respect to perioperative outcomes. Few studies have systemically assessed the body of evidence on this topic.

Methods: A systematic review of EMBASE and PubMed from database inception to December 2023 was performed to identify studies comparing MIS with open surgery for the treatment of spine metastases.

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Objective: Spinal cord injury (SCI) trials have historically underrepresented pediatric patients. There are limited pediatric data examining the influence of surgical timing on complications and mortality for children and adolescents who have sustained complete traumatic SCI.

Methods: The following multicenter cohort study used Trauma Quality Improvement Program data from 2010 to 2020.

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Article Synopsis
  • A phase II clinical study evaluated the effectiveness of a treatment combo (ibrutinib, bendamustine, and rituximab) in patients with relapsed or refractory aggressive B-cell non-Hodgkin lymphoma after stem cell transplants or in elderly patients.
  • The study showed a 49.1% overall response rate among patients who received at least one cycle, with better outcomes for those with relapsed disease (72.3%) versus refractory disease (37.8%).
  • Patients experiencing complete or partial responses had significantly longer median overall survival of 28.1 months, while common side effects included fatigue, diarrhea, and nausea, indicating that the treatment is both safe and effective for those needing potential transplantation.
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Objective: To determine the association between residence in racialized neighborhoods with direct healthcare expenditure and days at home (DAH) after moderate to severe traumatic brain injury (TBI).

Summary Background Data: Differences in ethno-racial background have been associated with health outcome disparities. Much of this prior research was conducted in settings without universal healthcare coverage.

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This study aims to estimate real-world clinical practice trends in time to surgery following thoracolumbar spinal cord injury (SCI) in trauma centers across North America over the last decade (2010-2020). A multi-center retrospective observational study was conducted using Trauma Quality Improvement Program data from 2010 to 2020. All surgically treated patients with thoracic and lumbar SCI were included.

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Article Synopsis
  • This study analyzes the time to surgery for patients with complete traumatic cervical spinal cord injuries in North America from 2010 to 2020, using data from trauma centers and focusing on the period post-hospital arrival.
  • Over the decade, the median time to spine surgery decreased by an average of 0.6 hours per year, indicating a trend towards quicker surgical intervention.
  • The research involved 6855 patients and showed a significant annual reduction of 5% in time to surgery, emphasizing the improvement in response time across accredited trauma centers.
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  • Dietary habits and food intake significantly influence obesity management, with the study highlighting variations between men and women in dietary behaviors related to weight loss.
  • Over a two-year analysis of 8,548 participants, it was found that individuals with obesity consumed more animal-based proteins and fewer plant-based proteins compared to normal-weight counterparts.
  • Specific foods, such as eggs and apples for men and women respectively, showed notable associations with weight reduction, enhancing understanding of sex-based dietary recommendations for effective weight loss strategies.
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Hospitalization Outcomes of Patients with Type 2 Diabetes Mellitus Complicated with Diabetic Ketoacidosis.

Isr Med Assoc J

October 2024

Department of Internal Medicine A, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Diabetic ketoacidosis (DKA) poses a significant medical emergency in both type 1 (T1DM) and type 2 diabetes mellitus (T2DM) patients. Recent attention has focused on the emergence of euglycemic DKA associated with sodium-glucose cotransporter-2 (SGLT2) inhibitors.

Objectives: To understand the epidemiology and outcomes of DKA, particularly in T2DM patients.

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Article Synopsis
  • GLP-1 receptor agonists (GLP-1RAs) slow down gastric emptying and may affect bowel preparation for colonoscopy, but their impact on bowel preparation adequacy was under-studied.
  • A multicenter study compared 4,876 patients using GLP-1RAs with 4,876 matched controls, finding that 10% of GLP-1RA users had inadequate bowel preparation (IBP), compared to just 4% of controls.
  • Results indicated that both diabetes and GLP-1RA usage independently increased the risk of IBP, suggesting that special attention is needed for these patients.
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Days at Home After Traumatic Brain Injury: Moving Beyond Mortality to Evaluate Patient-Centered Outcomes Using Population Health Data.

Neurology

October 2024

From the Division of Neurosurgery (A.K.M., H.S., R.H.J., A.E., F.M., E.Y.Y., C.D.W., J.R.W.), Unity Health; Li Ka Shing Knowledge Institute (A.K.M., H.S., F.M., C.D.W., J.R.W.); Institute for Health Policy, Management and Evaluation (A.K.M., A.B.N., H.S., R.H.J., K.T., A.V.K., C.D.W., J.R.W.), University of Toronto; Department of Surgery (A.B.N.), Sunnybrook Health Sciences Center, Toronto, Ontario, Canada; Division of Orthopedics (A.E.), Department of Surgery, Shamir Medical Center (Assaf Harofeh), Zerifin; Faculty of Medicine (A.E.), Tel Aviv University, Israel; Interdepartmental Division of Critical Care Medicine (F.M.), Unity Health; Division of Spine Surgery (J.H.B.), Sunnybrook Health Sciences Center; and Division of Neurosurgery (A.V.K.), Hospital for Sick Children, Toronto, Ontario, Canada.

Article Synopsis
  • The study aims to validate "days at home" (DAH) as an outcome measure for assessing recovery after moderate to severe traumatic brain injury (TBI) using administrative health data in Ontario, Canada.
  • It analyzed data from 6,340 patients between 2009 and 2021, finding that the median DAH was 70 days and 34.1% of patients died within 90 days of injury.
  • The research identifies factors significantly associated with fewer DAH, including older age, higher injury severity, and greater health resource utilization before the injury.
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The Perinatal Outcomes Following the October 7th Hamas-led Attack on Israel.

Isr Med Assoc J

September 2024

Department of Obstetrics and Gynecology, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel, affiliated with Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: On 7 October 2023, Hamas lunched a massive terror attack against Israel. The first weeks after were characterized with great uncertainty, insecurity, and fear.

Objectives: To evaluate the effect of the first 2 months of the Iron Swords war on obstetrical emergency attendance and the corresponding perinatal outcomes.

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Infracoccygeal/transperineal window: new method to prenatally diagnose and classify level of anal atresia.

Ultrasound Obstet Gynecol

October 2024

Obstetrics and Gynecology Ultrasound Unit, Maternity Hospital, Sheba Medical Center, Tel Hashomer, Ramat Gan, Israel.

Objectives: To introduce a two-dimensional sonographic method to assess the fetal anus, and to evaluate the feasibility of this method to diagnose anal atresia prenatally and identify the presence or absence of anoperineal fistula (in males) and anovestibular fistula (in females).

Methods: This was an observational study of suspected cases of anal atresia referred to a single center in Israel between August 2018 and October 2023. In addition to conventional evaluation of the perineum in the axial plane, fetuses referred to our center for suspected malformation were scanned with a new method termed the 'infracoccygeal/transperineal window'.

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Long-term Sperm Preservation: Exploring the Clinical, Economic, and Ethical Dimensions.

Isr Med Assoc J

August 2024

Sperm Bank and Andrology Unit, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel, Department of In Vitro Fertilization, Shamir Medical Center (Assaf Harofeh), Zerifin, Israel, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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The literature supports the benefits of medical cannabis for core and comorbid symptoms in autistic individuals and anxiety-related symptoms in individuals without autism. However, no study has specifically investigated how cannabidiol (CBD)-rich cannabis affects anxiety subtypes in autistic children or its relationship with restricted and repetitive behaviors and interests (RRBI). Understanding the effects of CBD-rich cannabis treatment on anxiety subtypes and RRBI could offer more precise treatment approaches to managing anxiety symptoms and reducing RRBI frequency in autistic children.

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Background: Healthcare inequities for patients with traumatic brain injury (TBI) represent a major priority area for trauma quality improvement. We hypothesized a relationship between health insurance status and timing of withdrawal of life sustaining treatment (WLST) for adults with severe TBI.

Methods: This multicenter retrospective observational cohort study utilized data collected between 2017 and 2020.

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Introduction: Medical cannabis treatment for autistic children has recently become popular, and studies have focused on examining the treatment's effects on children's symptom presentation, reported side effects, and dropout rates. However, no previous study has investigated the factors influencing adherence and dropout rates in cannabis treatment.

Method: This explanatory sequential mixed-methods study explored these factors by examining the characteristics of 87 autistic children and their families and deepening parents' perspectives and experiences of the 6-month CBD-rich cannabis treatment's benefits and barriers.

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Purpose:  Using liquid fibrin sealants has once again questioned the benefit of drain placement in head and neck operations. Cellulose-based hemostats offering different hemostasis mechanisms have scarcely been investigated in drainless neck surgeries. This study aimed to evaluate whether liquid fibrin sealant offers any advantage over cellulose-based hemostats in various head and neck surgeries.

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Amphetamine use for attention deficit hyperactive disorder during breastfeeding and children's neurodevelopmental outcomes: A pilot study.

Psychiatry Res

September 2024

Clinical Pharmacology and Toxicology Unit, Drug Consultation Center, Shamir Medical Center (Assaf Harofeh), Zerifin, Affiliated to Faculty of Medicine & Health Sciences, Tel Aviv University, Tel Aviv, Israel.

Attention deficit hyperactive disorder (ADHD) medication use rises among women of childbearing age and during pregnancy. Little is known on the safety of amphetamine stimulants for ADHD treatment during breastfeeding. Most data on the safety of these medications are from recreational abuse of methamphetamine.

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Background And Objective: While there is a substantial amount of research on risk perception, there has been less focus on the way medical technologies are perceived by experts as opposed to lay individuals. We investigated the factors that may influence the risk perception of healthcare workers (HCWs) and the general public regarding 3 distinct medical technologies: magnetic resonance imaging (MRI), laser-assisted in situ keratomileusis (LASIK) and the Covid-19 vaccine.

Methods: A cross-sectional study conducted in 2021 among 2 populations: HCWs employed at a general public hospital and a sample of outpatients and individuals who are not medical professionals.

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Article Synopsis
  • The study evaluates the thermal safety of the BeShape One Device, a noninvasive ultrasound tool for waist reduction, using a swine model to analyze temperature changes and tissue impact.
  • The research involved various applicators and included assessments such as clinical observations, skin reactions, and advanced temperature measurement techniques.
  • Results indicated that the device is safe, with no lasting adverse effects on the skin or surrounding tissues, confirming its potential for effective fat reduction without thermal damage.
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