15 results match your criteria: "Shaikh Zayed Post-Graduate Medical Institute[Affiliation]"

Article Synopsis
  • Multi-drug resistant (MDR) E. coli is a significant public health issue, especially in developing regions like the global south, with travelers spreading it to other areas.
  • A study in Punjab, Pakistan, involved 494 outpatients and 423 community members, analyzing the genetic diversity of E. coli and its antimicrobial resistance (AMR) by collecting and sequencing stool samples, resulting in 5,247 genomes from 1,411 samples.
  • The research found that the genetic lineages and AMR profiles of E. coli in the Punjabi population differed notably from those in high-income countries, and antibiotic use was linked to increased prevalence of MDR strains, highlighting the need for ongoing regional genomic surveillance to understand and manage this
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Apart from advances in pharmaceutical antidiabetic agents, efforts are being made toward hypoglycemic agents derived from natural sources. Cinnamon has been reported to have significant benefits for human health, particularly as an anti-inflammatory, antidiabetic, and anti-hypertriglyceridemic agent. The phytochemicals in cinnamon can be extracted from different parts of plant by distillation and solvent extraction.

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The aim of the study is to compare the outcomes among ST-segment elevation myocardial infarction (STEMI) cases with early treatment vs delayed treatment. It was a prospective comparative study on 186 patients with consecutive (nonprobability) sampling. Two groups of cases were made as per their time to get admitted to the hospital (ie, within 2 hours of symptom onset = Group A; after 2 hours of symptom onset = Group B).

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Article Synopsis
  • A clinical trial in Pakistan tested the effects of honey and Nigella sativa on COVID-19 patients, showing significant improvements compared to a placebo.
  • Patients receiving the treatment experienced a faster reduction in symptoms and quicker viral clearance, with moderate cases recovering in an average of 4 days versus 7 days for the placebo group.
  • The treatment also led to a lower mortality rate in severe cases (4%) compared to those on placebo, who had a mortality rate over 15%.
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Background: Coronavirus disease 2019 (COVID-19) caused by the novel coronavirus-infected millions globally. Despite a wide range of advised options for the treatment of COVID-19, a single strategy to tackle this pandemic remains elusive, thus far. That is why we are conducting a clinical trial to find out the efficacy of iodine complex to clear a viral load of severe respiratory syndrome coronavirus-2 (SARS-CoV-2) along with a reduction in time taken to alleviate symptoms.

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Multiple Myeloma is a clonal proliferation of plasma cells with bone marrow as the primary site of occurrence. Extramedullary multiple myeloma is uncommonly seen either at presentation or later during the course of the disease. Central nervous system involvement by multiple myeloma is an extremely rare entity with a dismal outcome.

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Objectives: Considering the therapeutic potential of honey and Nigella sativa (HNS) in coronavirus disease 2019 (COVID-19) patients, the objective of the study is defined to evaluate the prophylactic role of HNS.

Trial Design: The study is a randomized, placebo-controlled, adaptive clinical trial with parallel group design, superiority framework with an allocation ratio of 1:1 among experimental (HNS) and placebo group. An interim analysis will be done when half of the patients have been recruited to evaluate the need to adapt sample size, efficacy, and futility of the trial.

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Objectives: The study objective is to quantify the effectiveness of ivermectin (subcutaneous/oral IVM) in the presence or absence of zinc (Zn) for clinical and radiological improvement in coronavirus disease 2019 (COVID-19) patients with moderate severity.

Trial Design: This quadruple-blinded, placebo-controlled randomized clinical trial will be a multiarmed multi-centered study with superiority framework.

Participants: Quinquagenarian and sexagenarian patients with moderate COVID-19 symptoms and positive severe respiratory syndrome coronavirus -2 (SARS-CoV-2) PCR will be included.

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Objectives: The objective of the study is to measure the efficacy of ionic-iodine polymer complex [1] for clinical and radiological improvement in coronavirus disease 2019 (COVID-19) patients.

Trial Design: The trial will be closed label, randomized and placebo-controlled with a 1:1:1:1 allocation ratio and superiority framework.

Participants: All PCR confirmed COVID-19 adult patients including non-pregnant females, with mild to moderate disease, will be enrolled from Shaikh Zayed Post-Graduate Medical Complex, Ali Clinic and Doctors Lounge in Lahore (Pakistan).

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Cephalosporin resistance in community acquired spontaneous bacterial peritonitis.

Pak J Med Sci

January 2019

Anwaar A. Khan, MACP, FACG, FRCP, FCPS. Consultant Gastroenterologist, Doctors Hospital & Medical Center Ex- Dean and Professor of Gastroenterology, Shaikh Zayed Post Graduate Medical Institute, Lahore, Pakistan.

Objective: To determine 3 generation cephalosporin resistance in patients with community-acquired spontaneous bacterial peritonitis (SBP) using early response assessment.

Methods: This prospective quasi-experimental study was carried out at Doctors Hospital & Medical Center from January 2016 to September 2018. Patients with cirrhosis and SBP were included.

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This review focuses at highlighting the importance of Food Exchange List in cultural perspective, as an effective dietary tool to help individuals' manage their dietary modifications in relation to non communicable diseases whilst specifying measures that can help improve the quality of Food Exchange Lists for combating various non communicable diseases and addressing adherence related issues to specialized diets. A search was done using PubMed & Google Scholar till June 2016. Search terms used were food exchange list AND disease, diet AND non-communicable diseases.

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Background: Socio demographic factors besides dietary factors play important role in determining the health status of an individual. Health and nutritional Intervention programs stand a greater chance of success if planned, keeping the socio demographic characteristics of a certain population in focus. The present study was conducted to identify those socio demographic determinants which have a significant association with poor nutritional status in adolescent girls belonging to economically deprived households of Lahore.

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