3 results match your criteria: "Shahid Sadoughy University of Medical Sciences[Affiliation]"
Suppressing effects of green tea extract and Epigallocatechin-3-gallate (EGCG) on TGF-β- induced Epithelial-to-mesenchymal transition via ROS/Smad signaling in human cervical cancer cells.
Gene
August 2021
Department of Clinical Biochemistry, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address:
Background: Transforming growth factor-β (TGF-β)-induced Epithelial-to-mesenchymal transition (EMT) process is a fundamental target for preventing cervical cancer cells' progression and invasion. Green tea and its principal active substance, Epigallocatechin-3-gallate (EGCG), demonstrate anti-tumor activities in various tumor cells.
Methods: The cell viability of two cervical cancer cell lines, Hela and SiHa, in the experimental groups was examined employing the MTT method, and ROS generation was probed applying 2',7'-dichlorofluorescein diacetate-based assay.
Synergistic effects of green tea extract and paclitaxel in the induction of mitochondrial apoptosis in ovarian cancer cell lines.
Gene
June 2021
Department of Medical Radiation, Faculty of Engineering, Islamic Azad University, Science and Research Branch, Tehran, Iran. Electronic address:
Background: Green tea is a natural compound with anti-neoplastic properties. Paclitaxel (PTX) is a natural anti-tumor medication used to manage patients with advanced ovarian cancer. This manuscript evaluated the cytotoxic effects of green tea extract combined with PTX drug in two human ovarian cancer cell lines (p53-negative cell line, SKOV-3; and mutant type p53 cell line, OVCAR-3) and underlying mechanisms.
View Article and Find Full Text PDFDescription of an outbreak of acute sterile peritonitis in Iran.
Perit Dial Int
February 2011
Department of Nephrology, Shahid Sadoughy University of Medical Sciences, Yazd, Iran.
Article Synopsis
- Sterile or chemical peritonitis in patients undergoing continuous peritoneal dialysis (PD) is rare and not well-documented, making it important to analyze its characteristics.
- A study of 20 patients revealed that acute chemical peritonitis (ACP) was associated with cloudy dialysate and abdominal pain, with all cultures showing no microorganisms; symptoms resolved when glucose bags from a specific lot were changed.
- The results indicated that while there was a significant increase in dialysate-to-plasma creatinine levels after ACP episodes, glomerular filtration rates remained unchanged, highlighting the need for better monitoring of glucose degradation products in PD solutions.