Unlocking the Healing Potential: A Comprehensive Review of Ecology and Biology of Medical-Grade Honey in Wound Management and Tissue Regeneration.

Background And Aims: Honey has long been studied for its healing abilities in wound care. This narrative review examines its properties and their impact on wound healing, particularly its ability to accelerate wound closure and promote tissue regeneration. The review focuses on how honey's botanical origins affect its medical properties and wound-healing capabilities.

Bioactive Compounds and Antimicrobial Activities in Iranian Ecotypes for Potential Food and Medicinal Uses.

The genus , belonging to the Rosaceae family, exhibits widespread distribution across Iran, comprising 17 species. Hawthorn has garnered significant attention in recent years as a prominent herbal remedy in phytotherapy and culinary applications. Various plant parts, including flowers, leaves, and fruits, have been traditionally employed to address cardiovascular conditions such as hypertension, hypotension, palpitations, and cardiac arrhythmias.

Antioxidative properties, phenolic compounds, and in vitro protective efficacy of multi-herbal hydro-alcoholic extracts of ginger, turmeric, and thyme against the toxicity of aflatoxin B on mouse macrophage RAW264.7 cell line.

Aflatoxin B (AFB), the most potent toxic and carcinogenic secondary fungal metabolite, has frequently been reported in food/feed. Nowadays, herbal extracts are considered safe dietary additives to reduce the toxicity of such compounds. The protective capability of various combinations of hydro-alcoholic extracts (HAEs) of ginger, turmeric, and Shirazi thyme, against the toxicity of AFB on the RAW264.

Endocan as a biomarker for acute respiratory distress syndrome: A systematic review and meta-analysis.

Background And Aims: Endocan is a marker of endothelial damage. Data regarding the association of this proteoglycan and acute respiratory distress syndrome (ARDS) is discrepant. Hence, this study sought to investigate the possible correlation between serum/plasma endocan concentration and ARDS.

Emotion dysregulation as mediator between mentalizing capacity and affective states: An exploratory study.

Aim: We intended to elucidate the relationship between mentalizing capacity and affective states by investigating the mediatory role of emotion dysregulation.

Methods: A sample of nonclinical Iranian adults ( = 445) completed a battery of online self-report measures comprising the Positive and Negative Affect Schedule (PANAS), Mentalization Scale (MentS), and Difficulties in Emotion Regulation Scale (DERS).

Results: Correlational analyses demonstrated that self- and other-related mentalizing were significantly and inversely associated with emotion dysregulation, which in turn was strongly linked with positive and negative affects.

Energy-based corridor identification for mammals between protected areas in Iran.

Body mass plays a crucial role in determining the mass-specific energy expenditure during terrestrial locomotion across diverse animal taxa, affecting locomotion patterns. The energy landscape concept offers a framework to explore the relationship between landscape characteristics and energy expenditure, enhancing our understanding of animal movement. Although the energy landscape approach solely considers the topographic obstacles faced by animals, its suitability compared to previous methods for constructing resistance maps and delineating corridors has not been comprehensively examined.

The relationship between perceived stress and pregnancy distress with self-care of pregnant women: The mediating role of social support-A cross-sectional study.

Background And Aims: Pregnancy is a stressful experience, which can affect different aspects of a woman's life. Yet, women with a supportive network of friends and family may experience lower stress and improved self-care behavior. The study aimed to investigate the relationship between perceived stress and pregnancy distress with the self-care of pregnant women, as well as the mediating role of social support.

Prevalence of depression among Iranian children and adolescents: An updated systematic review and meta-analysis.

Background And Aims: One of the most common mental disorders among children and adolescent is depression. Some of the conducted studies indicate a too-high prevalence of depression, which cannot be generalized to the entire country. So the pooled estimation of the results of different studies is very important to reach valid results.

Sexual and reproductive health-related questions and concerns of newly married couples: A qualitative content analysis.

Background And Aims: Approximately half of Iranian marring couples have poor sexual knowledge and attitudes. This article delves into the main concerns and queries regarding sexual and reproductive health among Iranian newly married couples.

Methods: We conducted a content analysis of the sexual and reproductive health questions and concerns that were anonymously submitted by newly married couples to the researcher via social media in 2021-2022.

An evaluation of isolation by distance and isolation by resistance on genetic structure of the Persian squirrel () in the Zagros forests of Iran.

For the conservation of wild species, it is important to understand how landscape change and land management can affect gene flow and movement. Landscape genetic analyses provide a powerful approach to infer effects of various landscape factors on gene flow, thereby informing conservation actions. The Persian squirrel is a keystone species in the woodlands and oak forests of Western Asia, where it has experienced recent habitat loss and fragmentation.

Occlusion of femoral artery using Foley catheter: A REBOA inspired tale to save a life.

In this case report, we emphasized the need to control bleeding in emergency departments by any measure possible, as it is the first step toward successful resuscitation for saving the lives of patients with active bleeding.

Optimization of ultrasonic Bath and cold plasma pre-treatments in the spearmint essential oil isolation process.

Spearmint essential oil (SEO), one of the economically valuable natural products, has special importance in the food, pharmaceutical, and perfumery industries due to its antifungal, antioxidant, and enzyme inhibitory properties. In this study, we optimized and evaluated the effect of three pre-treatments on the extraction of SEO for quantity and quality: ultrasonic bath (UB), water to material ratio-ultrasonic bath (W/M-UB), and cold plasma-ultrasonic bath (CP-UB). Three experiments were designed using the central composite design (CCD) of response surface methodology (RSM).

Mineral lick use by a community of large herbivores in northern Iran.

Natural mineral licks are ecologically valuable resources to meet the physiological needs of herbivores, particularly in temperate forests. Importantly, licking sites can harbor high anthropogenic risk for conservation-dependent herbivores through higher chance of pathogen spillover from livestock and increased levels of poaching risks. However, to the best of our knowledge, there is no information on the mineral lick use in temperate forests of west Asia and the Caucasus where a few threatened deer species exist.

Fabrication of Au/FeO/RGO based aptasensor for measurement of miRNA-128, a biomarker for acute lymphoblastic leukemia (ALL).

Due to their high sensitivity, simplicity, portability, self-contained, and low cost, the development of electrochemical biosensors is a beneficial way to diagnose and anticipate many types of cancers. An electrochemical nanocomposite-based aptasensor is fabricated for the determination of miRNA-128 concentration as the acute lymphoblastic leukemia (ALL) biomarker for the first time. The aptamer chains were immobilized on the surface of the glassy carbon electrode (GCE) through gold nanoparticles/magnetite/reduced graphene oxide (AuNPs/FeO/RGO).

Development of a Multiepitope Vaccine Against SARS-CoV-2: Immunoinformatics Study.

Background: Since the first appearance of SARS-CoV-2 in China in December 2019, the world witnessed the emergence of the SARS-CoV-2 outbreak. Due to the high transmissibility rate of the virus, there is an urgent need to design and develop vaccines against SARS-CoV-2 to prevent more cases affected by the virus.

Objective: A computational approach is proposed for vaccine design against the SARS-CoV-2 spike (S) protein, as the key target for neutralizing antibodies, and envelope (E) protein, which contains a conserved sequence feature.

Effect of low-pressure cold plasma processing on decontamination and quality attributes of Saffron ( L.).

This study investigated the microbial decontamination of saffron using the low-pressure cold plasma (LPCP) technology. Therefore, other quality characteristics of saffron that create the color, taste, and aroma have also been studied. The highest microbial log reduction was observed at 110 W for 30 min.

Convergent regional brain abnormalities in behavioral variant frontotemporal dementia: A neuroimaging meta-analysis of 73 studies.

Introduction: Numerous studies have reported brain alterations in behavioral variant frontotemporal dementia (bvFTD). However, they pointed to inconsistent findings.

Methods: We used a meta-analytic approach to identify the convergent structural and functional brain abnormalities in bvFTD.

Ultra pH-sensitive detection of total and free prostate-specific antigen using electrochemical aptasensor based on reduced graphene oxide/gold nanoparticles emphasis on TiO/carbon quantum dots as a redox probe.

The development of a rapid, sensitive, and straightforward detection method of prostate-specific antigen (PSA) is indispensable for the early diagnosis of prostate cancer (PCa). This work relates an electrochemical method using functionalized single-stranded DNA aptamer to diagnose PCa and benign prostate hyperplasia. The sensing platform relies on PSA recognition by aptamer/Au/GO-nanohybrid-modified glassy carbon electrode.

Diversity and distribution of Epeorus (Caucasiron) (Ephemeroptera, Heptageniidae) in Iran, with descriptions of three new species.

Combining morphological and molecular data in an integrative approach, three new mayfly species of Epeorus (Caucasiron) are described. These include Epeorus (Caucasiron) alborzicus Hrivniak & Sroka, and Epeorus (Caucasiron) shargi Hrivniak & Sroka, from northern Iran, and Epeorus (Caucasiron) zagrosicus Hrivniak & Sroka, from central Iran. They are unambiguously delimited using both distance-based and likelihood-based approaches in the analyses of barcode COI sequences.

New Oligoneuriidae (Insecta, Ephemeroptera) from Iran.

Two new species of the mayfly family Oligoneuriidae are described based on larval specimens recently collected in Iran. The first new species, Godunko & Staniczek, , can be distinguished from all its congeners by the presence of pronounced protuberances posteromedially on abdominal terga, highly reduced paracercus, large lamella of gill I, and setation on hind margin of middle and hind femora confined to their basal halves. The second species, Bojková, Godunko, & Staniczek, , remarkably belongs to a mostly Afrotropical genus.

Intelligent Computer Systems for Multiple Sclerosis Diagnosis: a Systematic Review of Reasoning Techniques and Methods.

Objective: Intelligent computer systems are used in diagnosing Multiple Sclerosis and help physicians in the accurate and timely diagnosis of the disease. This study focuses on a review of different reasoning techniques and methods used in intelligent systems to diagnose MS and analyze the application and efficiency of different reasoning methods in order to find the most efficient and applicable methods and techniques for MS diagnosis.

Methods: A complete research was carried out on articles in various electronic databases based on Mesh vocabulary.

Rosmarinic acid-loaded electrospun nanofibers: In vitro release kinetic study and bioactivity assessment.

This study seeks to develop a nanofibrous matrix containing rosmarinic acid (RosA), an herbal non-steroidal anti-inflammatory and antioxidant drug with low water solubility, for drug delivery applications. Neat and two types of RosA-loaded cellulose acetate (CA) mats varying in the initial content of RosA were electrospun. Microstructure of nanofibers, chemistry and physical state of RosA in nanofibers, RosA loading efficiency and RosA release in acetate buffer were investigated.